Model DetailsLung adenoma

Model Name

Lung adenoma

Strain

A/J

Tumor Inducing Agent(s)

Chemical/Drug : urethane (ethyl carbamate)

Tumor Synonyms

solid adenoma  •  lung adenoma  •  benign adenoma  •  pulmonary adenoma  •  papillary adenoma  •  lung lesion  •  lung tumor  •  pulmonary neoplasm

Strain Synonyms

A  •  A/J-Jax  •  Strain A  •  A/J, H-2a  •  A/Lilly  •  A/Jax  •  AJ  •  strain A  •  A/Cloudman
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Lung Male

100%

(30 of 30 mice)
9.5-10 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63
Lung Unspecified

100%

(38 of 38 mice)
24-34 weeks
  • Notes

    Reproductive Status: reproductive status not specified

Malkinson AM, J Natl Cancer Inst 1985 Nov;75(5):971-4
Lung Unspecified

observed

12-50 weeks
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Horio Y, Mol Carcinog 1996 Dec;17(4):217-23
Lung Male

60%

(18 of 30 mice)
31-33 weeks
  • Notes

    Reproductive Status: reproductive status not specified

McNeill DA, Drug Chem Toxicol 1990;13(1):87-92
Lung Male

90%

(9 of 10 mice)
28-30 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McNeill DA, Drug Chem Toxicol 1990;13(1):71-86
Lung Male

80%

(8 of 10 mice)
28-30 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McNeill DA, Drug Chem Toxicol 1990;13(1):71-86
Lung Male

90%

(9 of 10 mice)
53-55 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McNeill DA, Drug Chem Toxicol 1990;13(1):71-86
Lung Male

90%

(9 of 10 mice)
53-55 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

McNeill DA, Drug Chem Toxicol 1990;13(1):71-86
Lung Unspecified

observed

12 months
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4
Lung Unspecified

very high

22 weeks
  • Notes

    Reproductive Status: reproductive status not specified

Thaete LG, Cancer Lett 1991 Dec 9;61(1):15-20
Lung Unspecified

very high

 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
Mason RJ, Am J Pathol 2000 Jan;156(1):175-82
Lung Male

very high

8.5 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    18 weeks

  • Pathology Reports
Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50
Lung Mixed Population

100%

(76 of 76 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6
Lung Mixed Population

100%

(12 of 12 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6
Lung Mixed Population

100%

(5 of 5 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6
Lung Mixed Population

100%

(3 of 3 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6
Lung Male

observed

 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ruch RJ, Exp Lung Res 2001 Apr-May;27(3):231-43
Lung Male

observed

30.5-35 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Pathology Reports
  • Gene Expression Data
Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75