Strain Summary(129S1/SvImJ x C57BL/6)F1-Trp53^tm3.1Glo/+

Strain Name	(129S1/SvImJ x C57BL/6)F1-Trp53^tm3.1Glo/+
Strain Type(s)	hybrid • targeted mutation (knock-in)
Strain Synonym(s)	129Sl • 129SL • 129Sl C57Bl/6 F-1 hybrid Trp53^R172H heterozygote • 129Sl C57Bl/6 F-1 p53 R172H • 129Sl F-1
Description	Heterozygous mice. The genetic background of these mice was (129S1/SvImJ x C57BL/6)F1 hybrid with a small contribution from 129S7/SvEvBrd-Hprt⁺ from the original generation of the mutant allele.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm3.1Glo allele Trp53^tm3.1Glo / Trp53⁺

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adipose tissue tumor	Adipose tissue				2		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
Blood vessel hemangioma	Blood vessel				2		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
Bone osteosarcoma	Bone				6		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
Leukocyte lesion	Leukocyte				10		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast				0		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
(Unspecified organ) adenocarcinoma	(Unspecified organ)				2		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
(Unspecified organ) carcinoma	(Unspecified organ)				2		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):
(Unspecified organ) tumor	(Unspecified organ)		38	28	2 - 33		References: Chan CS, Life Sci Alliance 2021 Mar;4(3):

Models