Strain SummaryC57BL/6-Apc^tm1Mmt/+

Strain Name	C57BL/6-Apc^tm1Mmt/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Min
Description	Heterozygous Apc mice on a C57BL/6 background with contribution from 129S2/SvPas.
Strain Genetics	List all models in MMHCdb carrying the Apc^tm1Mmt allele Apc^tm1Mmt / Apc⁺

Models
12 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal	Bacteroides fragilis			72.97 - 100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal				very low		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal	Bacteroides fragilis ⋅ anti-PD-L1 (Cd274)			100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal	Bacteroides fragilis			0 - 100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal	Bacteroides fragilis ⋅ anti-PD-L1 (Cd274)			100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	Bacteroides fragilis			observed		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon adenoma - microadenoma	Intestine - Large Intestine - Colon	Bacteroides fragilis			58.33		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon adenoma - microadenoma	Intestine - Large Intestine - Colon				very low		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon adenoma - tubular	Intestine - Large Intestine - Colon	Bacteroides fragilis			observed		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Bacteroides fragilis			observed - 100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon				very low		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Bacteroides fragilis ⋅ anti-PD-L1 (Cd274)			100		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():