Strain SummaryNMRI-Foxn1nu

Strain Name

 NMRI-Foxn1nu

Strain Type(s)

 spontaneous mutation

Strain Synonym(s)

 NMRI-Foxn1nu/Foxn1nu  •  NMRI-Foxn1nu/nu  •  NMRInude

Description

 Homozygous Foxn1nu on an NMRI background with possible albino stock contribution.

Strain Genetics

 Foxn1nu / Foxn1nu

Models

26 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung carcinoma - large cell neuroendocrine Lung Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - large cell neuroendocrine Lung Qfrt Y4 Linear-Cationic polymer Y4 Linear carrying RNAP guides for Rb, Rb1l, Pten, Trp53 and frt

0 - observed

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - large cell neuroendocrine Lung Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

22

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - small cell lung (SCLC) Lung Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

observed - 75

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung carcinoma - small cell lung (SCLC) Lung Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

observed - 22

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung hyperplasia - neuroendocrine Lung Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

0

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Lung hyperplasia - neuroendocrine Lung Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

observed - 10

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Skin - Dorsal region tumor Skin - Dorsal region mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Facial region papilloma Skin - Facial region mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Facial region tumor Skin - Facial region mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Hair follicle trichoblastoma Skin - Hair follicle mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Tail papilloma Skin - Tail mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Tail papilloma - exophytic Skin - Tail mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Tail tumor Skin - Tail mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin papilloma Neck mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin papilloma Leg mouse papillomavirus (MmuPV1)

observed

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin papilloma Skin mouse papillomavirus (MmuPV1)

observed

References: Sundberg J, Personal Communication 1997;():

17 pathology image(s)
Trachea carcinoma Trachea Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

22

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Trachea carcinoma - small cell lung (SCLC) Trachea Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

observed - 56

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Trachea carcinoma - small cell lung (SCLC) Trachea Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

observed

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) carcinoma - large cell neuroendocrine (Unspecified organ) Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

25

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor (Unspecified organ) Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

44 - 75

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Sites of Metastasis: (Unspecified organ) , Liver
(Unspecified organ) tumor (Unspecified organ) Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

10 - 22

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

Sites of Metastasis: (Unspecified organ) , Liver
(Unspecified organ) tumor Liver Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

33

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor Lymph node Q Y4Linear-Cationic polymer Y4Linear carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

10

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121

(Unspecified organ) tumor Liver Q Y4L5-Cationic polymer Y4L5 carrying RNAP guides for Rb, Rb1l, Pten, and Trp53.

10

References: Lara-Saez I, Proc Natl Acad Sci U S A 2024 Jul 9;121(28):e2322917121