Strain Summary(C57BL/6J x PWK/PhJ)F1-Tg(TRAMP)8247Ng
Strain Name |
(C57BL/6J x PWK/PhJ)F1-Tg(TRAMP)8247Ng |
Strain Type(s) |
hybrid • transgenic |
Strain Synonym(s) |
C57BL/6-Tg(TRAMP)8247Ng/J x PWK/PhJ F1 • PB-TAg • TRAMP F1 • TRAMP-PWK • TRAMP x PWK/PhJ F1 |
Description |
These mice were generated by crossing C57BL/6-Tg(TRAMP)8247Ng/J female mice with PWK/PhJ male mice. |
Strain Genetics |
Tg(TRAMP)8247Ng |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Prostate gland - Anterior lobe hyperplasia | Prostate gland - Anterior lobe |
observed |
References: Patel SJ, PLoS One 2013;8(4):e61848 |
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Prostate gland - Dorsolateral lobe hyperplasia | Prostate gland - Dorsolateral lobe |
observed |
References: Patel SJ, PLoS One 2013;8(4):e61848 |
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Prostate gland carcinoma - neuroendocrine | Prostate gland |
0 - 25 |
References: Patel SJ, PLoS One 2013;8(4):e61848 Sites of Metastasis: Lung |
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Prostate gland hyperplasia | Prostate gland |
67 - 100 |
References: Patel SJ, PLoS One 2013;8(4):e61848 |
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Prostate gland prostatic intraepithelial neoplasia (PIN) | Prostate gland |
67 - 100 |
References: Patel SJ, PLoS One 2013;8(4):e61848 |
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Seminal vesicle hyperplasia | Seminal vesicle |
0 - 100 |
References: Patel SJ, PLoS One 2013;8(4):e61848 |
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Seminal vesicle tumor | Seminal vesicle |
observed |
References: Patel SJ, PLoS One 2013;8(4):e61848 |
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Seminal vesicle tumor - phyllodes-like | Seminal vesicle |
50 |
References: Patel SJ, PLoS One 2013;8(4):e61848 |