Strain Summary[not specified]-Apc^tm2Rak Msh2^tm2.1Rak

Strain Name	[not specified]-Apc^tm2Rak Msh2^tm2.1Rak
Strain Type(s)	targeted mutation (conditional)
Strain Synonym(s)	Adenoviral-Cre Apc^-/- Msh2^-/-
Description	Homozygous Msh2 & Apc mutant, transgenic mice on an unspecified background with possible contributions from "129/Sv", C57BL/6J, and/or SJL.
Strain Genetics	List all models in MMHCdb carrying the Apc^tm2Rak allele Apc^tm2Rak / Apc^tm2Rak
	List all models in MMHCdb carrying the Msh2^tm2.1Rak allele Msh2^tm2.1Rak / Msh2^tm2.1Rak

Models
11 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon adenocarcinoma	Intestine - Large Intestine - Colon	Adenovirus carrying cre recombinase				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon adenocarcinoma - intramucosal	Intestine - Large Intestine - Colon	Adenovirus carrying cre recombinase				0	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	Adenovirus carrying cre recombinase				observed - 100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon	Adenovirus carrying cre recombinase ⋅ BEZ235 (NVP-BEZ235-AN)				100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Adenovirus carrying cre recombinase				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	Adenovirus carrying cre recombinase				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine adenocarcinoma - intramucosal	Intestine - Large Intestine	Adenovirus carrying cre recombinase				0	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine adenoma	Intestine - Large Intestine	Adenovirus carrying cre recombinase				observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine adenoma	Intestine - Large Intestine	Adenovirus carrying cre recombinase ⋅ BEZ235 (NVP-BEZ235-AN)				100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine neoplasm	Intestine - Large Intestine	Adenovirus carrying cre recombinase				100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine - Large Intestine tumor	Intestine - Large Intestine	Adenovirus carrying cre recombinase				100	References: Kucherlapati MH, PLoS One 2013;8(7):e68817