Strain SummaryC57BL/6-Brca1tm2Cxd Trp53tm1Brd/+ Tg(MMTV-cre)4Mam

Strain Name

C57BL/6-Brca1tm2Cxd Trp53tm1Brd/+ Tg(MMTV-cre)4Mam

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

Brca1tm1Cxd/Brca1tm2Cxd;Trp53tm1Brd/Trp53+;Tg(MMTV-cre)4Mam/0  •  C57Bl6_MMTV_Cre_Brca1CoCo_p53het  •  C57Bl6_MMTV_Cre_BRCA1CoCo_p53het  •  Brca1Co/Co;TgMMTV-Cre;p53+/-  •  TgMMTV-Cre Brca1Co/Co, Trp53+/?


Compound mutant mice. The genetic background of these mice was predominantly C57BL/6. It also contained some 129S6/SvEvTac, some 129S7/SvEvBrd-Hprt+, some FVB, and possibly some other strain(s).

Strain Genetics

Trp53tm1Brd / Trp53+
Brca1tm2Cxd / Brca1tm2Cxd


1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland carcinoma Mammary gland


References: Herschkowitz JI, Genome Biol 2007;8(5):R76