Strain SummaryC57BL/6-Tg(TRAMP)8247Ng/J

Strain Name

 C57BL/6-Tg(TRAMP)8247Ng/J

Strain Type(s)

 transgenic

Strain Synonym(s)

 B6 TRAMP mice  •  C57BL/6J-Tg(TRAMP)824Ng/J  •  PB-TAg  •  probasin/Tag  •  TRAMP  •  TRAMP-B6

Description

 Transgenic mice expressing the SV40 early genes (TAg) under control of the prostate epithelium-specific rat probasin promoter. The founder line (#8247) was generated on a C57BL/6 background.

Strain Links

 • JAX Mice

Strain Genetics

 Tg(TRAMP)8247Ng

Models

14 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Brainstem medulloblastoma CNS - Brain - Brainstem

observed

References: Sundberg J, Personal Communication 1997;():

CNS - Brain - Brainstem tumor CNS - Brain - Brainstem

observed

References: Sundberg J, Personal Communication 1997;():

CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum

observed

References: Sundberg J, Personal Communication 1997;():

4 pathology image(s)
CNS - Brain medulloblastoma CNS - Brain

observed

References: Sundberg J, Personal Communication 1997;():

3 pathology image(s)
CNS - Brain tumor CNS - Brain

observed

References: Sundberg J, Personal Communication 1997;():

Prostate gland - Anterior lobe hyperplasia Prostate gland - Anterior lobe

observed

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland - Dorsolateral lobe hyperplasia Prostate gland - Dorsolateral lobe

observed

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland carcinoma - neuroendocrine Prostate gland

0 - 64

References: Patel SJ, PLoS One 2013;8(4):e61848

Sites of Metastasis: Kidney , Liver , Lung , Lymph node

4 pathology image(s)
Prostate gland hyperplasia Prostate gland

100

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

100

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland tumor Prostate gland

observed

References: Deeb KK, Cancer Res 2007 Sep 1;67(17):8065-8080   ⋅   Sundberg J, Personal Communication 1997;():

Seminal vesicle hyperplasia Seminal vesicle

0 - 100

References: Patel SJ, PLoS One 2013;8(4):e61848

Seminal vesicle tumor Seminal vesicle

observed

References: Patel SJ, PLoS One 2013;8(4):e61848

Seminal vesicle tumor - phyllodes Seminal vesicle

observed

References: Deeb KK, Cancer Res 2007 Sep 1;67(17):8065-8080