Strain SummaryC57BL/6J-ApcMin/+
Strain Name |
C57BL/6J-ApcMin/+ |
Strain Type(s) |
chemically induced mutation |
Strain Synonym(s) |
Apc/Min • Apcmin • B6-Apc+/ApcMin • B6 ApcMin/Apc+ • B6-ApcMin/Apc+ • B6-Apc+/ApcMin • B6 Min/+ • B6-Min/+ • B6.Min/+ • B6 Min • B6-Min • B6-Min (ApcMin/Apc+) • C57BL/6-ApcMin/+ • C57BL/6-Min/+ • C57BL/6J-ApcMin/+Apc • C57BL/6J-ApcMin/+ • C57BL/6J-ApcMin • C57BL/6 J-Min/+ • C57BL/6J Min/+ • C57BL/6J(Min/+) • C57BL/6J-Min/+ • C57BL/6J.Min/+ • C57BL/6j Min • C57BL/6J Min • Apc+/- • Apc mutant Min • ApcMin/+ • ApcMin/+ • ApcMin • ApcMIN • Apc+/- • Apc+/ApcMin • ApcMin/Apc+ • ApcMin • APCMin • ApcMin/Apc+ • Apc+/ApcMin • ICRF MIN • Min • Min/+ • Min • MIN • multiple intestinal neoplasia • multiple intestinal neoplasia/+ |
Description |
Heterozygous mice - "Min" mutation. Background is C57BL/6J. |
Strain Genetics |
ApcMin / Apc+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Connective tissue - Fibroblast desmoid | Skin |
15 |
References: Smits R, Gastroenterology 1998 Feb;114(2):275-83 |
|||||
Intestine - Large Intestine - Colon - Distal adenoma | Intestine - Large Intestine - Colon - Distal |
observed |
References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 |
|||||
Intestine - Large Intestine - Colon - Proximal adenoma | Intestine - Large Intestine - Colon - Proximal |
observed |
References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 |
|||||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon |
observed - 52 |
observed - 52 |
observed |
observed - 91 |
References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66 ⋅ Dove WF, Cancer Res 1997 Mar 1;57(5):812-4 ⋅ Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5 ⋅ Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 ⋅ Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8 ⋅ Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Moser AR, Science 1990 Jan 19;247(4940):322-4 ⋅ Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | celecoxib |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | folate-deficient |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | folate-supplemented |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | azoxymethane (AOM) |
observed |
observed |
References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5 |
|||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) |
38 |
100 |
observed |
References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66 |
||
Intestine - Large Intestine - Colon adenoma | Intestine - Large Intestine - Colon | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
50 |
92 |
observed |
References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66 |
||
Intestine - Large Intestine - Colon carcinoma | Intestine - Large Intestine - Colon | troglitazone |
observed |
References: Saez E, Nat Med 1998 Sep;4(9):1058-61 |
||||
Intestine - Large Intestine - Colon carcinoma | Intestine - Large Intestine - Colon |
observed |
References: Saez E, Nat Med 1998 Sep;4(9):1058-61 |
|||||
Intestine - Large Intestine - Colon dysplasia | Intestine - Large Intestine - Colon | azoxymethane (AOM) |
observed |
References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5 |
||||
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) | Intestine - Large Intestine - Colon | folate-deficient |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) | Intestine - Large Intestine - Colon |
0 - observed |
0 - observed |
observed |
References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5 ⋅ Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
|||
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) | Intestine - Large Intestine - Colon | folate-supplemented |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) | Intestine - Large Intestine - Colon | azoxymethane (AOM) |
observed |
observed |
References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5 |
|||
Intestine - Large Intestine - Colon hyperplasia | Intestine - Large Intestine - Colon | azoxymethane (AOM) |
observed |
References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5 |
||||
Intestine - Large Intestine - Colon polyp | Intestine - Large Intestine - Colon |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
|||||
Intestine - Large Intestine - Colon polyp | Intestine - Large Intestine - Colon | low vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Large Intestine - Colon polyp | Intestine - Large Intestine - Colon | high vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | troglitazone |
observed |
References: Saez E, Nat Med 1998 Sep;4(9):1058-61 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon |
32 |
47 - 52 |
observed - 30 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 ⋅ Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40 ⋅ Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82 ⋅ Saez E, Nat Med 1998 Sep;4(9):1058-61 |
|||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | sulindac |
observed |
References: Saez E, Nat Med 1998 Sep;4(9):1058-61 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
50 - 71 |
80 - 100 |
57 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 ⋅ Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40 ⋅ Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82 |
||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) ⋅ retinoic acid (RA) |
58 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | retinoic acid (RA) |
53 - 80 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 |
||||
Intestine - Large Intestine adenoma | Intestine - Large Intestine |
observed |
References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6 |
|||||
Intestine - Large Intestine polyp | Intestine - Large Intestine |
observed |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 ⋅ Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Intestine - Large Intestine polyp | Intestine - Large Intestine | increased fat, decreased fiber |
observed |
References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Intestine - Large Intestine polyp | Intestine - Large Intestine | high fat |
observed |
References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Intestine - Large Intestine polyp | Intestine - Large Intestine | vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Large Intestine polyp | Intestine - Large Intestine | vitamin D3 (1alpha,25-(OH)2-D3) (VD3) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Large Intestine polyp | Intestine - Large Intestine | sulindac |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Distal adenoma | Intestine - Small Intestine - Distal |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
|||||
Intestine - Small Intestine - Distal adenoma | Intestine - Small Intestine - Distal | celecoxib |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Small Intestine - Distal adenoma | Intestine - Small Intestine - Distal | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal | vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal | vitamin D3 (1alpha,25-(OH)2-D3) (VD3) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal | sulindac |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 ⋅ Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
|||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal | low vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine - Distal polyp | Intestine - Small Intestine - Distal | high vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine - Distal tumor | Intestine - Small Intestine - Distal |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
|||||
Intestine - Small Intestine - Distal tumor | Intestine - Small Intestine - Distal | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Distal tumor | Intestine - Small Intestine - Distal | piroxicam ⋅ difluoromethylornithine (DFMO) |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Distal tumor | Intestine - Small Intestine - Distal | difluoromethylornithine (DFMO) |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Duodenum adenoma | Intestine - Small Intestine - Duodenum |
observed - 99 |
References: Dove WF, Cancer Res 1997 Mar 1;57(5):812-4 ⋅ Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Moser AR, Science 1990 Jan 19;247(4940):322-4 ⋅ Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
|||||
Intestine - Small Intestine - Duodenum adenoma | Intestine - Small Intestine - Duodenum | folate-deficient |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine - Duodenum adenoma | Intestine - Small Intestine - Duodenum | folate-supplemented |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine - Duodenum neoplasia | Intestine - Small Intestine - Duodenum |
observed |
References: Sundberg J, Personal Communication 1997;(): 1 pathology image(s) |
|||||
Intestine - Small Intestine - Duodenum polyp | Intestine - Small Intestine - Duodenum |
observed |
References: Sundberg J, Personal Communication 1997;(): 1 pathology image(s) |
|||||
Intestine - Small Intestine - Ileum adenoma | Intestine - Small Intestine - Ileum |
observed - 97 |
References: Dove WF, Cancer Res 1997 Mar 1;57(5):812-4 ⋅ Klein IK, Cancer Res 2000 Apr 15;60(8):2077-80 ⋅ Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Moser AR, Science 1990 Jan 19;247(4940):322-4 ⋅ Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
|||||
Intestine - Small Intestine - Ileum adenoma | Intestine - Small Intestine - Ileum | folate-deficient |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine - Ileum adenoma | Intestine - Small Intestine - Ileum | folate-supplemented |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine - Jejunum adenoma | Intestine - Small Intestine - Jejunum |
observed |
References: Dove WF, Cancer Res 1997 Mar 1;57(5):812-4 ⋅ Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8 ⋅ Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
|||||
Intestine - Small Intestine - Jejunum adenoma | Intestine - Small Intestine - Jejunum | folate-deficient |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine - Jejunum adenoma | Intestine - Small Intestine - Jejunum | folate-supplemented |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine - Jejunum neoplasia | Intestine - Small Intestine - Jejunum |
observed |
References: Sundberg J, Personal Communication 1997;(): 1 pathology image(s) |
|||||
Intestine - Small Intestine - Jejunum polyp | Intestine - Small Intestine - Jejunum |
observed |
References: Sundberg J, Personal Communication 1997;(): 1 pathology image(s) |
|||||
Intestine - Small Intestine - Medial adenoma | Intestine - Small Intestine - Medial |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
|||||
Intestine - Small Intestine - Medial adenoma | Intestine - Small Intestine - Medial | celecoxib |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Small Intestine - Medial adenoma | Intestine - Small Intestine - Medial | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Small Intestine - Medial polyp | Intestine - Small Intestine - Medial | vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Medial polyp | Intestine - Small Intestine - Medial | vitamin D3 (1alpha,25-(OH)2-D3) (VD3) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Medial polyp | Intestine - Small Intestine - Medial | sulindac |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Medial polyp | Intestine - Small Intestine - Medial |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 ⋅ Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
|||||
Intestine - Small Intestine - Medial polyp | Intestine - Small Intestine - Medial | low vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine - Medial polyp | Intestine - Small Intestine - Medial | high vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine - Medial tumor | Intestine - Small Intestine - Medial |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
|||||
Intestine - Small Intestine - Medial tumor | Intestine - Small Intestine - Medial | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Medial tumor | Intestine - Small Intestine - Medial | piroxicam ⋅ difluoromethylornithine (DFMO) |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Medial tumor | Intestine - Small Intestine - Medial | difluoromethylornithine (DFMO) |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Proximal adenoma | Intestine - Small Intestine - Proximal |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
|||||
Intestine - Small Intestine - Proximal adenoma | Intestine - Small Intestine - Proximal | celecoxib |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Small Intestine - Proximal adenoma | Intestine - Small Intestine - Proximal | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal | vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal | vitamin D3 (1alpha,25-(OH)2-D3) (VD3) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal | sulindac |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 ⋅ Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
|||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal | low vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine - Proximal polyp | Intestine - Small Intestine - Proximal | high vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine - Proximal tumor | Intestine - Small Intestine - Proximal |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
|||||
Intestine - Small Intestine - Proximal tumor | Intestine - Small Intestine - Proximal | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Proximal tumor | Intestine - Small Intestine - Proximal | piroxicam ⋅ difluoromethylornithine (DFMO) |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine - Proximal tumor | Intestine - Small Intestine - Proximal | difluoromethylornithine (DFMO) |
observed |
References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine |
100 |
100 |
observed |
observed |
References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6 ⋅ Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | folate-deficient |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | folate-supplemented |
observed |
References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) |
100 |
100 |
observed |
References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66 |
||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
100 |
100 |
observed |
References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66 |
||
Intestine - Small Intestine neoplasia | Intestine - Small Intestine |
observed |
References: Sundberg J, Personal Communication 1997;(): 5 pathology image(s) |
|||||
Intestine - Small Intestine polyp | Intestine - Small Intestine |
observed |
observed |
observed |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 ⋅ Saez E, Nat Med 1998 Sep;4(9):1058-61 ⋅ Sundberg J, Personal Communication 1997;(): ⋅ Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 5 pathology image(s) |
||
Intestine - Small Intestine polyp | Intestine - Small Intestine | increased fat, decreased fiber |
observed |
References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Intestine - Small Intestine polyp | Intestine - Small Intestine | high fat |
observed |
References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Intestine - Small Intestine polyp | Intestine - Small Intestine | troglitazone |
observed |
References: Saez E, Nat Med 1998 Sep;4(9):1058-61 |
||||
Intestine - Small Intestine polyp | Intestine - Small Intestine | low vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine polyp | Intestine - Small Intestine | high vitamin |
observed |
References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15 |
||||
Intestine - Small Intestine tumor | Intestine - Small Intestine | sulindac |
observed |
References: Saez E, Nat Med 1998 Sep;4(9):1058-61 |
||||
Intestine - Small Intestine tumor | Intestine - Small Intestine | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
100 |
100 |
observed - 100 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 ⋅ Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40 ⋅ Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82 |
||
Intestine - Small Intestine tumor | Intestine - Small Intestine |
100 |
observed - 100 |
100 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 ⋅ Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40 ⋅ Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82 |
|||
Intestine - Small Intestine tumor | Intestine - Small Intestine | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) ⋅ retinoic acid (RA) |
100 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 |
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Intestine - Small Intestine tumor | Intestine - Small Intestine | retinoic acid (RA) |
100 |
References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53 |
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Intestine adenocarcinoma | Intestine |
0 |
References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 |
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Intestine adenoma | Intestine |
observed |
observed - 100 |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 ⋅ Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8 ⋅ Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52 ⋅ Luongo C, Genes Chromosomes Cancer 1996 Nov;17(3):194-8 ⋅ Moser AR, J Cell Biol 1992 Mar;116(6):1517-26 ⋅ Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9 ⋅ Su LK, Science 1992 May 1;256(5057):668-70 |
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Intestine adenoma | Intestine | gamma-radiation |
100 |
References: Luongo C, Genes Chromosomes Cancer 1996 Nov;17(3):194-8 |
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Intestine adenoma | Intestine | celecoxib |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine adenoma | Intestine | piroxicam |
observed |
References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4 |
||||
Intestine dysplasia | Intestine |
observed |
References: Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8 |
|||||
Intestine neoplasia | Intestine |
observed |
References: Sundberg J, Personal Communication 1997;(): 7 pathology image(s) |
|||||
Intestine polyp | Intestine | vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
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Intestine polyp | Intestine | vitamin D3 (1alpha,25-(OH)2-D3) (VD3) |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine polyp | Intestine | sulindac |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 |
||||
Intestine polyp | Intestine |
observed |
observed |
References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6 ⋅ Sundberg J, Personal Communication 1997;(): 7 pathology image(s) |
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Intestine tumor | Intestine | N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU) |
very high |
References: Shoemaker AR, Cancer Res 1997 May 15;57(10):1999-2006 |
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Intestine tumor | Intestine | ethylnitrosourea (ENU) |
100 |
References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5 |
||||
Mammary gland carcinoma | Mammary gland |
observed |
References: Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81 |
|||||
Mammary gland carcinoma | Mammary gland | N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU) |
0 - 37.5 |
References: Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81 |
||||
Mammary gland lesion | Mammary gland | ethylnitrosourea (ENU) |
38 |
References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5 |
||||
Mammary gland tumor | Mammary gland |
0 - 41 |
References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5 ⋅ Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81 ⋅ Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
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Mammary gland tumor | Mammary gland | increased fat, decreased fiber |
20 |
References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Mammary gland tumor | Mammary gland | high fat |
26 |
References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13 |
||||
Mammary gland tumor | Mammary gland | ethylnitrosourea (ENU) |
93 |
References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5 |
||||
Skin gland - Sebaceous gland cyst | Skin gland - Sebaceous gland |
92 |
References: Smits R, Gastroenterology 1998 Feb;114(2):275-83 |