Strain SummaryAKR
Strain Name |
AKR |
Strain Type(s) |
inbred |
Strain Synonym(s) |
Afb • Ak • Akm • R.I.L. • RIL • Rockefeller Institute Leukemia |
Description |
Substrain not specified. |
Strain Links |
• Festing's List of Inbred Strains |
Strain Genetics |
Thy1a / Thy1a |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Bone osteoma | Bone |
observed |
observed |
References: Furth J, J Gerontol 1946;1():46-54 |
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Bone osteoma | Bone | thymectomy |
observed |
observed |
References: Furth J, J Gerontol 1946;1():46-54 |
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Bone osteosarcoma | Bone |
observed |
References: Franks LM, J Natl Cancer Inst 1973 Feb;50(2):431-8 |
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Leukocyte - Lymphocyte leukemia - lymphocytic | Leukocyte - Lymphocyte |
4 - 65 |
high - 57 |
84 |
66.0 - 91.0 |
References: Fekete E, Cancer Res 1954;14():445-47 ⋅ Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 ⋅ Staats J, Cancer Res 1985 Mar;45(3):945-77 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): ⋅ Staats J, Companion to Mouse News Lett No. 25 1961;(): |
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Leukocyte - Lymphocyte leukemia - lymphocytic | Thymus |
83 |
68 |
90 |
References: Staats J, Companion to Mouse News Lett No. 33 1965;(): |
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Leukocyte - Lymphocyte lymphohematopoietic neoplasm | Leukocyte - Lymphocyte |
high |
References: Murphy ED, 1966;():521-62 |
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Leukocyte leukemia | Leukocyte |
80.0 - 100 |
70.0 - 80.0 |
high - 92.0 |
References: Duran-Reynals ML, J Natl Cancer Inst 1974 Mar;52(3):1001-3 ⋅ Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Furth J, J Gerontol 1946;1():46-54 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 ⋅ Heston WE, 1963;():247-68 ⋅ International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): |
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Leukocyte leukemia | Leukocyte | thymectomy |
11 |
9 |
References: Furth J, J Gerontol 1946;1():46-54 |
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Leukocyte leukemia | Leukocyte | mainstream cigarette smoke (MCS) |
100 |
References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 |
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Leukocyte lymphoma | Leukocyte |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
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Liver - Hepatocyte preneoplastic lesion | Liver - Hepatocyte | N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN) |
observed |
References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7 |
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Liver carcinoma in situ | Liver | N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN) |
observed |
References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7 |
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Liver hepatocellular carcinoma - well-differentiated | Liver | N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN) |
observed |
References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7 |
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Liver hyperplasia | Liver | N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN) |
observed |
References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7 |
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Lung tumor | Lung |
0 |
1 |
1 |
References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 |
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Mammary gland adenocarcinoma | Mammary gland |
0 - 1 |
0 |
1 |
References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 |
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Thymus leukemia | Thymus |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
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Thymus lymphoma | Thymus |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |