Strain SummaryC.129S2(B6)-Trp53tm1Tyj/J
Strain Name |
C.129S2(B6)-Trp53tm1Tyj/J |
Strain Type(s) |
congenic • targeted mutation (knockout) |
Strain Synonym(s) |
BALB/cJ-Trp53tm1Tyj • BALB-p53?/? • C.129S2(B6)-Trp53tm1Tyj • C.129S2-Trp53tm1Tyj/J • p53&delta • p53-/- |
Description |
Homozygous mice. These mice have been fully backcrossed onto BALB/cJ. The original mutation was generated using 129S2/SvPas ES cells and was crossed to C57BL/6 before being backcrossed to BALB/cJ. |
Strain Links |
• JAX Mice |
Strain Genetics |
Trp53tm1Tyj / Trp53tm1Tyj |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Adrenal gland - Cortex carcinoma | Adrenal gland - Cortex |
observed |
References: Mikaelian I, Personal Communication 2002;(): Sites of Metastasis: Kidney , Liver 5 pathology image(s) |
|||||
Blood vessel hemangiosarcoma | Blood vessel |
26 |
25 |
25 |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||
Bone osteosarcoma | Bone |
9.7 |
0 |
4.8 |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||
Leukocyte - Lymphocyte lymphoma | Lymph node |
observed |
References: Mikaelian I, Personal Communication 2003;(): Sites of Metastasis: Lung 3 pathology image(s) |
|||||
Leukocyte lymphoma | Leukocyte |
74 |
84 |
79 - 80 |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||
Leukocyte lymphoma | Thymus |
observed |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||||
Mammary gland carcinoma | Mammary gland |
6.5 |
0 |
3.2 |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||
Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
observed |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||||
(Unspecified organ) carcinoma | (Unspecified organ) |
observed |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||||
(Unspecified organ) sarcoma | (Unspecified organ) |
9.7 |
3.1 |
6.3 |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |
|||
(Unspecified organ) tumor | (Unspecified organ) |
9.7 |
6.25 |
100 |
References: Landuzzi L, Oncotarget 2014 Dec 15;5(23):11924-38 |