Strain SummaryC3HeB/FeJ
Strain Name |
C3HeB/FeJ |
Strain Type(s) |
embryo transfer • inbred |
Strain Synonym(s) |
C3Fe • C3H • C3HeB/FeJ MMTV- • C3HeB/FeJ-MTV- • C3HFe • C3H Fekete • C3H/HeBFeJ • C3H/HeBFeJ mtv- • C3HeB/FeJax • C3He/JFe • HeB • MTV- • TC3H |
Description |
C3H embryo transferred to C57BL/6. These mice do not carry MMTV. |
Strain Links |
• Mouse Phenome Database (MPD)
• Festing's List of Inbred Strains • JAX Mice |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla | corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
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| Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla | diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
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| Bone - Skull osteosarcoma | Bone - Skull | diethylstilbestrol (DES) ⋅ corn oil |
observed - 2.7 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
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| Bone hyperplasia | Bone | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
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| Bone hyperplasia | Bone | diethylstilbestrol (DES) ⋅ corn oil |
5.56 - 97.3 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
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| Bone osteosarcoma | Bone | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Bone osteosarcoma | Bone | diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Eye - Harderian gland adenocarcinoma | Eye - Harderian gland |
1.0 |
References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8 |
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| Eye - Harderian gland adenoma - acinar | Eye - Harderian gland |
0.5 |
References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8 |
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| Eye - Harderian gland adenoma - cystic | Eye - Harderian gland |
0.5 |
References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8 |
|||||
| Eye - Harderian gland adenoma - cystic papillary | Eye - Harderian gland |
1.0 |
References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8 |
|||||
| Eye - Harderian gland adenoma - papillary | Eye - Harderian gland |
2.0 |
References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8 |
|||||
| Eye - Harderian gland tumor | Eye - Harderian gland |
5.1 |
References: Sheldon WG, J Natl Cancer Inst 1983 Jul;71(1):61-8 |
|||||
| Leukocyte leukemia | Leukocyte |
0 - 6.9 |
References: Myers DD, Life Sci 1970;9(Pt II):1071-80 |
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| Liver hepatocellular adenoma | Liver | MMTV - mouse mammary tumor virus ⋅ corn oil |
1.45 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Liver hepatocellular adenoma | Liver | MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
2.13 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
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| Liver hepatocellular carcinoma | Liver | MMTV - mouse mammary tumor virus ⋅ corn oil |
10.14 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Liver hepatocellular carcinoma | Liver | MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
5.33 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Liver hepatoma | Liver |
observed - 31 |
References: Staats J, Companion to Mouse News Lett No. 29 1963;(): ⋅ Storer JB, J Gerontol 1966 Jul;21(3):404-9 |
|||||
| Liver tumor | Liver |
observed |
References: Storer JB, J Gerontol 1966 Jul;21(3):404-9 |
|||||
| Mammary gland adenocarcinoma | Mammary gland | corn oil |
0 - 51.28 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Mammary gland adenocarcinoma | Mammary gland | diethylstilbestrol (DES) ⋅ corn oil |
0 - 60 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Mammary gland adenocarcinoma - acinar | Mammary gland |
observed |
References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s) |
|||||
| Mammary gland adenocarcinoma - type B | Mammary gland |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Mammary gland carcinoma | Mammary gland | corn oil |
8.11 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Mammary gland hyperplasia - alveolar | Mammary gland |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Mammary gland hyperplasia - alveolar | Mammary gland | corn oil |
0 - 5.41 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Mammary gland hyperplasia - alveolar | Mammary gland | diethylstilbestrol (DES) ⋅ corn oil |
0 - 70 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Mammary gland tumor | Mammary gland |
observed |
low |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13 ⋅ Staats J, Cancer Res 1985 Mar;45(3):945-77 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): ⋅ Storer JB, J Gerontol 1966 Jul;21(3):404-9 |
||||
| Mammary gland tumor | Mammary gland | MMTV - mouse mammary tumor virus |
high |
References: Staats J, Cancer Res 1985 Mar;45(3):945-77 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): |
||||
| Mammary gland tumor | Mammary gland | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Mammary gland tumor | Mammary gland | diethylstilbestrol (DES) ⋅ corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Mesothelium mesothelioma | Uterus | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Mesothelium mesothelioma | Uterus | diethylstilbestrol (DES) ⋅ corn oil |
0 - observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary - Germ cell teratoma | Ovary - Germ cell | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary - Germ cell teratoma | Ovary - Germ cell | diethylstilbestrol (DES) ⋅ corn oil |
0 - observed |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary - Granulosa cell tumor | Ovary - Granulosa cell | corn oil |
5.3 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary adenoma - tubular | Ovary | corn oil |
0 - 36.36 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary adenoma - tubular | Ovary | diethylstilbestrol (DES) ⋅ corn oil |
0 - 50 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary luteoma | Ovary | corn oil |
2.1 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Ovary tumor | Ovary |
22 - 64 |
References: Murphy ED, 1966;():521-62 ⋅ Staats J, Cancer Res 1985 Mar;45(3):945-77 ⋅ Staats J, Companion to Mouse News Lett No. 25 1961;(): |
|||||
| Pancreas - Islet of Langerhans adenoma | Pancreas - Islet of Langerhans | corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Pancreas - Islet of Langerhans adenoma | Pancreas - Islet of Langerhans | diethylstilbestrol (DES) ⋅ corn oil |
0 - observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Pituitary gland adenoma | Pituitary gland | corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Pituitary gland adenoma | Pituitary gland | diethylstilbestrol (DES) ⋅ corn oil |
0 - observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Skin - Epidermis - Basal cell carcinoma | Skin - Epidermis - Basal cell |
observed |
References: Sundberg J, Personal Communication 1997;(): 5 pathology image(s) |
|||||
| Skin squamous cell carcinoma | Skin | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Skin squamous cell carcinoma | Skin | diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Thyroid gland carcinoma | Thyroid gland | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Thyroid gland carcinoma | Thyroid gland | diethylstilbestrol (DES) ⋅ corn oil |
0 - observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Uterus - Cervix | corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Uterus - Cervix | diethylstilbestrol (DES) ⋅ corn oil |
observed - 5.56 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Uterus - Cervix | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Urinary bladder | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Urethra | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Ureter | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Vagina | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Intestine - Large Intestine - Rectum | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix adenocarcinoma | Uterus | 17beta-estradiol (E2) ⋅ MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix hyperplasia | Uterus - Cervix | 17beta-estradiol (E2) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus - Cervix lesion | Uterus - Cervix | corn oil |
0 - 14.29 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix lesion | Uterus - Cervix | diethylstilbestrol (DES) ⋅ corn oil |
0 - 100 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix lesion | Uterus - Cervix | 17beta-estradiol (E2) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus - Cervix myoblastoma - granular cell | Uterus - Cervix | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix myoblastoma - granular cell | Uterus - Cervix | diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix squamous cell carcinoma | Uterus - Cervix | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Cervix squamous cell carcinoma | Uterus - Cervix | diethylstilbestrol (DES) ⋅ corn oil |
0 - observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Endometrium carcinoma | Uterus - Endometrium | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Endometrium carcinoma | Uterus - Endometrium | MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Endometrium hyperplasia | Uterus - Endometrium | 17beta-estradiol (E2) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus - Endometrium polyp | Uterus - Endometrium | corn oil |
1.47 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Endometrium polyp | Uterus - Endometrium | MMTV - mouse mammary tumor virus ⋅ diethylstilbestrol (DES) ⋅ corn oil |
5.25 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Uterine horn adenoacanthoma | Uterus - Uterine horn | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Uterine horn adenoacanthoma | Uterus - Uterine horn | diethylstilbestrol (DES) ⋅ corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Uterine horn adenocarcinoma | Uterus - Uterine horn | corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Uterine horn adenocarcinoma | Uterus - Uterine horn | diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus - Uterine horn hyperplasia - glandular | Uterus - Uterine horn | corn oil |
11.11 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus - Uterine horn hyperplasia - glandular | Uterus - Uterine horn | diethylstilbestrol (DES) ⋅ corn oil |
5.13 - 94.59 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus - Uterine horn lesion | Uterus - Uterine horn | corn oil |
16.67 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus - Uterine horn lesion | Uterus - Uterine horn | diethylstilbestrol (DES) ⋅ corn oil |
5.13 - 86.49 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
||||
| Uterus adenocarcinoma | Uterus | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus adenocarcinoma | Uterus | diethylstilbestrol (DES) ⋅ corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus atypia | Uterus | 17beta-estradiol (E2) ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Uterus hyperplasia - glandular | Uterus |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Uterus preneoplastic lesion | Uterus | 17beta-estradiol (E2) ⋅ diethylstilbestrol (DES) ⋅ corn oil |
observed |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Vagina squamous cell carcinoma | Vagina | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| Vagina squamous cell carcinoma | Vagina | diethylstilbestrol (DES) ⋅ corn oil |
observed - 2.7 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 ⋅ Highman B, J Environ Pathol Toxicol 1980 Nov;4(5-6):81-95 |
||||
| (Unspecified organ) tumor | (Unspecified organ) |
55 |
31 |
References: Storer JB, J Gerontol 1966 Jul;21(3):404-9 |
||||
| (Unspecified organ) tumor - malignant | (Unspecified organ) | corn oil |
0 |
References: Highman B, J Environ Pathol Toxicol 1978 Sep-Oct;1(1):1-30 |
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