Strain SummaryB6.129-Apctm1Rak/+ Trp53tm1Tyj/+

Strain Name

B6.129-Apctm1Rak/+ Trp53tm1Tyj/+

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

C57BL/6-Apctm1Rak/+ Trp53tm1Tyj/+  •  Apc+/Apc1638N p53 heterozygote  •  Apc+/Apc1638N-p53+/p53-

Description

Compound mutant mice. These mice are the product of an intercross between strains on a predominantly C57BL/6JIco background where the mice were subsequently backcrossed to C57BL/6JIco.

Strain Genetics

Trp53tm1Tyj / Trp53+
Apctm1Rak / Apc+

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast desmoid Muscle - Striated - Skeletal

100

References: Smits R, Gastroenterology 1998 Feb;114(2):275-83