Strain SummarySENCAR
Strain Name |
SENCAR |
Strain Type(s) |
outbred |
Strain Synonym(s) |
CR:ORL SENCAR |
Description |
"SENsitivity to CARcinogenesis". This outbred stock was selectively bred to be susceptible to cancer initiation with DMBA and promotion with TPA (Boutwell RK, Prog. Exp. Tumor Res. 4, 207-250, 1964). |
Strain Genetics |
|
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Adrenal gland - Cortex adenoma | Adrenal gland - Cortex | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Adrenal gland - Cortex hyperplasia - focal | Adrenal gland - Cortex | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
9.09 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Adrenal gland - Subcapsular cell hyperplasia - spindle cell | Adrenal gland - Subcapsular cell | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
77.27 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Adrenal gland hyperplasia | Adrenal gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Blood vessel hemangioma | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Blood vessel hemangiosarcoma | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Blood vessel hemangiosarcoma | Blood vessel | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
10.71 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Connective tissue - Fibroblast fibroma | Uterus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Connective tissue - Fibroblast fibrosarcoma | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Eye - Harderian gland adenoma | Eye - Harderian gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
5.17 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Eye - Harderian gland tumor | Eye - Harderian gland | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
7.14 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Intestine - Small Intestine adenoma | Intestine - Small Intestine | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Kidney lesion | Kidney | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell hyperplasia | Thymus - Medulla | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma | Lymph node | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
6.90 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma | Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
10.71 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma | Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - follicular | Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
6.90 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - follicular | Thymus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
5.17 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - follicular | Spleen | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
6.90 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - B-lymphocyte hyperplasia | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte - T-lymphocyte hyperplasia | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte hyperplasia | Thymus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte hyperplasia | Spleen | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed - 63.16 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte hyperplasia | Lymph node | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
60.53 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte hyperplasia | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed - 33.93 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte hyperplasia | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Lymphocyte hyperplasia | Thymus - Cortex | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
16.67 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Uterus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed - 22.41 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 Sites of Metastasis: Adrenal gland , Intestine - Small Intestine , Kidney , Liver , Lung , Lymph node , Ovary , Pancreas |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
22.41 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Vagina | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 Sites of Metastasis: Lung |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Uterus - Cervix | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 Sites of Metastasis: Lung |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
7.14 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Leukocyte - Monocyte - Macrophage - Histiocyte |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Leukocyte - Myelocyte (Granulocyte) hyperplasia | Spleen - Red pulp | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Myelocyte (Granulocyte) metaplasia | Spleen | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
80.70 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte - Myelocyte (Granulocyte) metaplasia | Lymph node | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
11.9 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte lymphoma | Leukocyte | 7,12-dimethylbenz[a]anthracene (DMBA) |
25 - 75 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Leukocyte lymphoma | Leukocyte |
5 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
|||||
| Leukocyte lymphoma | Leukocyte | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 - 7.14 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Leukocyte lymphoma - histiocytic | Leukocyte | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Liver - Bile duct cyst | Liver - Bile duct | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
5.36 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Liver foci - basophilic | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Liver hepatocellular adenoma | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
6.9 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Liver hepatocellular adenoma | Liver |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Liver hyperplasia | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
64.29 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Liver lesion | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Liver tumor | Liver | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung - Bronchiole hyperplasia | Lung - Bronchiole | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
26.79 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung adenocarcinoma | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
4.76 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung adenocarcinoma - papillary | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 Sites of Metastasis: Mammary gland |
||||
| Lung adenoma | Lung |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Lung adenoma - papillary | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
5.17 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung adenoma - solid | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
10.34 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung carcinoma | Lung |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Lung foci | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung tumor | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed - 18.97 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung tumor | Lung | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
14.29 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung tumor - papillary | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lung tumor - solid | Lung | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lymph node hyperplasia | Lymph node | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Lymph node hyperplasia - follicular | Lymph node | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland adenoacanthoma | Mammary gland | 7,12-dimethylbenz[a]anthracene (DMBA) |
0 - 5 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Mammary gland adenoacanthoma | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland adenocarcinoma | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
4.76 - 18.97 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland adenocarcinoma - type A | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
6.90 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland adenocarcinoma - type B | Mammary gland | 7,12-dimethylbenz[a]anthracene (DMBA) |
5 - 20 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Mammary gland adenocarcinoma - type B | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
8.62 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland carcinoma | Mammary gland | 7,12-dimethylbenz[a]anthracene (DMBA) |
10 - 65 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Mammary gland carcinoma | Mammary gland |
0 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
|||||
| Mammary gland carcinoma - undifferentiated | Mammary gland | 7,12-dimethylbenz[a]anthracene (DMBA) |
5 - 10 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Mammary gland carcinoma in situ - ductal | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland metaplasia - squamous | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland tumor | Mammary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
18.97 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland tumor | Mammary gland | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
3.57 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Mammary gland tumor | Mammary gland |
observed |
References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 |
|||||
| Mesodermal cell/mesoblast sarcoma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
7.14 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Muscle - Smooth leiomyosarcoma | Uterus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Muscle myoma | Muscle | 7,12-dimethylbenz[a]anthracene (DMBA) |
very low |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Muscle myoma | Muscle |
0 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
|||||
| Ovary cyst - simple macrocyst | Ovary | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
90.91 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Ovary tumor | Ovary | 7,12-dimethylbenz[a]anthracene (DMBA) |
very low |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Ovary tumor | Ovary |
0 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
|||||
| Pancreas - Islet of Langerhans hyperplasia | Pancreas - Islet of Langerhans | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
35.42 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Pituitary gland adenoma | Pituitary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
2.38 - 5.17 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Pituitary gland tumor | Pituitary gland | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Pituitary gland tumor | Pituitary gland | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
7.14 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin - Epidermis hyperplasia | Skin - Epidermis | 7,12-dimethylbenz[a]anthracene (DMBA) |
75 |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 |
||||
| Skin - Epidermis hyperplasia - focal | Skin - Epidermis | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin - Hair follicle hyperplasia | Skin - Hair follicle | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
observed |
References: Binder RL, Mol Carcinog 1997 Sep;20(1):151-8 ⋅ Sundberg JP, Cancer Res 1994 Mar 1;54(5):1344-51 |
||||
| Skin carcinoma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
observed |
References: Woodworth CD, Carcinogenesis 2004 Sep;25(9):1771-8 |
||||
| Skin carcinoma | Skin | cigarette smoke condensate (CSC) |
0 - 3.4 |
References: Gaworski CL, Toxicology 1999 Nov 29;139(1-2):1-17 |
||||
| Skin carcinoma - poorly differentiated | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
7.14 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin hyperplasia | Skin |
0 |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 |
|||||
| Skin hyperplasia | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) |
0 |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 |
||||
| Skin lesion | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
7.24 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin papilloma | Skin |
0 |
References: Sundberg JP, Cancer Res 1994 Mar 1;54(5):1344-51 |
|||||
| Skin papilloma | Skin | 7,12-dimethylbenz[a]anthracene (DMBA) |
0 |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 ⋅ Sundberg JP, Cancer Res 1994 Mar 1;54(5):1344-51 |
||||
| Skin papilloma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) |
0 - 8.3 |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 ⋅ Sundberg JP, Cancer Res 1994 Mar 1;54(5):1344-51 |
||||
| Skin papilloma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
observed |
References: Woodworth CD, Carcinogenesis 2004 Sep;25(9):1771-8 |
||||
| Skin papilloma | Skin | acetone |
3.33 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin papilloma | Skin | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin papilloma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
observed - 25 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin squamous cell carcinoma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
17.86 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin squamous cell hyperplasia | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
0 - 100 |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 ⋅ Binder RL, Mol Carcinog 1997 Sep;20(1):151-8 |
||||
| Skin squamous cell hyperplasia | Skin | 7,12-dimethylbenz[a]anthracene (DMBA) |
0 - observed |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 |
||||
| Skin squamous cell papilloma | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
observed - very high |
References: Binder RL, Cancer Res 1998 Oct 1;58(19):4314-23 ⋅ Binder RL, Mol Carcinog 1997 Sep;20(1):151-8 ⋅ Sundberg JP, Cancer Res 1994 Mar 1;54(5):1344-51 |
||||
| Skin squamous cell papilloma - pedunculated | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
observed - very high |
References: Binder RL, Mol Carcinog 1997 Sep;20(1):151-8 ⋅ Sundberg JP, Cancer Res 1994 Mar 1;54(5):1344-51 |
||||
| Skin tumor | Skin | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
0 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Skin tumor | Skin | 7,12-dimethylbenz[a]anthracene (DMBA) |
0 - 3.3 |
References: Gaworski CL, Toxicology 1999 Nov 29;139(1-2):1-17 |
||||
| Skin tumor | Skin | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA) |
30 - 93.3 |
References: Gaworski CL, Toxicology 1999 Nov 29;139(1-2):1-17 |
||||
| Skin tumor | Skin | cigarette smoke condensate (CSC) |
0 - 97.1 |
References: Gaworski CL, Toxicology 1999 Nov 29;139(1-2):1-17 |
||||
| Stomach adenoma - polypoid | Stomach | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Thymus - Medulla cyst | Thymus - Medulla | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
31.58 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Thymus - Medulla cyst - epithelial | Thymus - Medulla | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Thymus hyperplasia | Thymus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
89.47 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Thymus hyperplasia - epithelial | Thymus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Thyroid gland - Follicular cell adenoma | Thyroid gland - Follicular cell | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Tongue papilloma | Tongue | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Uterus - Endometrium hyperplasia - cystic | Uterus - Endometrium | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
83.02 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Uterus - Endometrium polyp | Uterus - Endometrium | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
3.45 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| Uterus - Endometrium tumor | Uterus - Endometrium | 7,12-dimethylbenz[a]anthracene (DMBA) |
very low |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
||||
| Uterus - Endometrium tumor | Uterus - Endometrium |
0 |
References: Qing WG, Carcinogenesis 1997 Mar;18(3):553-9 |
|||||
| Uterus adenocarcinoma | Uterus | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
1.72 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| (Unspecified organ) lesion | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed - 70.69 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| (Unspecified organ) reticulum cell sarcoma | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| (Unspecified organ) tumor | (Unspecified organ) | formalin (37-40% formaldehyde solution in acetone) ⋅ acetone |
observed - 22.41 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||
| (Unspecified organ) tumor | (Unspecified organ) | 12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ acetone |
17.86 |
References: Ward JM, Environ Health Perspect 1986 Sep;68():81-9 |
||||