Reference SummaryMurphy ED, 1966;():521-62

Title

 Characteristic Tumors

Authors

 Murphy ED

Journal

Volume

Issue

Year

 1966

Pages

 521-62

Abstract

Links

 J:24830 – MGI References

Strain Notes

Strain Note
C3H Mice were carriers of infectious MMTV.
C3HeB/De Mice were NOT carriers of infectious MMTV.
C3Hf/He Mice were NOT carriers of infectious MMTV.
C3H/He Mice were carriers of infectious MMTV.
DBA Mice were carriers of infectious MMTV.
DBA/2 Mice were carriers of infectious MMTV.
DBA/2eBDe Mice were NOT carriers of infectious MMTV.
DD Mice were carriers of infectious MMTV.
DD/He Mice were carriers of infectious MMTV.

Models
Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
WB/Re Adipose tissue liposarcoma Adipose tissue

observed
DBA Adrenal gland - Cortex hyperplasia - nodular Adrenal gland - Cortex

observed
CE/J Adrenal gland - Cortex tumor
  • ovariectomy
 Adrenal gland - Cortex

100
CE/J Adrenal gland - Cortex tumor
  • castration
 Adrenal gland - Cortex

79
C3HeB/De Adrenal gland - Cortex tumor Adrenal gland - Cortex

4.8
DBA/2eBDe Adrenal gland - Cortex tumor Adrenal gland - Cortex

1.3
CE Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
(DBA x CE)F1 Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
BALB/c Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
NH Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
CBA Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
C3H Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
A Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed
C3HeB/De Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.2
wild mice Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.9 - 2.8
(C3H x I)F1 Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

observed
HR/De Hrhr/+ Blood vessel hemangioendothelioma Blood vessel

24
C3HeB/De Blood vessel hemangioendothelioma Blood vessel

1.2 - 5.2
C3Hf/He Blood vessel hemangioendothelioma Blood vessel

2 - 3.0
C57BL/He Blood vessel hemangioendothelioma Blood vessel

2.0
DBA/2eBDe Blood vessel hemangioendothelioma Blood vessel

12 - 16
HR/De Hrhr/? Blood vessel hemangioendothelioma Blood vessel

14 - 29
wild mice Blood vessel hemangioendothelioma Blood vessel

2.8 - 8.1
C3Hf/He Bone osteosarcoma Bone

1 - 1
wild mice Bone osteosarcoma Bone

1.4
(BALB/c x C3H)F1 CNS - Brain - Undifferentiated cell glioblastoma CNS - Brain - Undifferentiated cell

observed
C57BL CNS - Brain - Undifferentiated cell medulloblastoma CNS - Brain - Undifferentiated cell

observed
C57BL CNS - Brain glioma CNS - Brain

observed
C57BL/He Clitoral gland tumor Clitoral gland

1
C3H/He Eye - Harderian gland tumor Eye - Harderian gland

1
C3HeB/De Eye - Harderian gland tumor Eye - Harderian gland

4.8
DBA/2eBDe Eye - Harderian gland tumor Eye - Harderian gland

2.0
HR/De Hrhr/? Eye - Harderian gland tumor Eye - Harderian gland

2.1
BALB/c Kidney adenocarcinoma Kidney

40
C3Hf/He Kidney carcinoma Kidney

1
C3HeB/De Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

1.2
DBA/2eBDe Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

1.3
C3H Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

observed
AKR/Lw Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

92
C58/Lw Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

90
C3HeB/De Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

1.0
C3Hf/He Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

1
C57BL/He Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

3.0
DBA/2eBDe Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

2.6 - 7.8
HR/De Hrhr/? Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

5.8 - 7.9
wild mice Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

2.0
AKR Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

high
C58 Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

high
C57BL/He Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

15
C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

0.6 - 2.0
DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

9.8 - 12
HR/De Hrhr/? Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

3.2 - 6.3
wild mice Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

1
C57BL Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

15.0 - 20.0
SJL/J Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

high - 91
C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

1.9
C57BL/He Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

11
DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

7.9 - 18
HR/De Hrhr/? Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

1.9 - 6.3
wild mice Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

5.0 - 12
C57L/He Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

25
wild mice Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell

1.0
DBA/2eBDe Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

1.3 - 2.0
RF Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic
  • ionizing radiation
 Leukocyte - Myelocyte (Granulocyte)

observed
C3HeB/De Liver hepatoma Liver

30 - 91
C3Hf/He Liver hepatoma Liver

17 - 25
C57BL/He Liver hepatoma Liver

1
DBA/2eBDe Liver hepatoma Liver

5.3
HR/De Hrhr/? Liver hepatoma Liver

1.6 - 12
wild mice Liver hepatoma Liver

2.8 - 9.3
C3H Liver hepatoma Liver

moderate
CBA Liver hepatoma Liver

moderate
C3H/He Liver hepatoma Liver

85
C3HeB Liver hepatoma Liver

58 - 91
A Lung - Alveolus tumor Lung - Alveolus

high
SWR Lung - Alveolus tumor Lung - Alveolus

high
BALB/c Lung - Alveolus tumor Lung - Alveolus

high
A Lung tumor Lung

90
SWR Lung tumor Lung

80
C3HeB/De Lung tumor Lung

3.7 - 24
C3Hf/He Lung tumor Lung

6.0 - 10
C57BL/He Lung tumor Lung

1.0
DBA/2eBDe Lung tumor Lung

3.9
HR/De Hrhr/? Lung tumor Lung

3.2 - 17
wild mice Lung tumor Lung

15 - 28
C3HeB/De Mammary gland adenoacanthoma Mammary gland

17 - 28
C3Hf/He Mammary gland adenoacanthoma Mammary gland

9.6
C3HeB/De Mammary gland adenocarcinoma - type A Mammary gland

17 - 26
C3Hf/He Mammary gland adenocarcinoma - type A Mammary gland

18
wild mice Mammary gland adenocarcinoma - type A Mammary gland

3.0
C3H Mammary gland adenocarcinoma - type A
  • MMTV - mouse mammary tumor virus
 Mammary gland

observed
C3HeB/De Mammary gland adenocarcinoma - type B Mammary gland

4.0 - 28
C3Hf/He Mammary gland adenocarcinoma - type B Mammary gland

19
DBA/2eBDe Mammary gland adenocarcinoma - type B Mammary gland

5.9
wild mice Mammary gland adenocarcinoma - type B Mammary gland

2.0
DBA/2eBDe Mammary gland adenocarcinoma - type C Mammary gland

2.6
C3HeB/De Mammary gland carcinoma Mammary gland

4.0 - 74
C3Hf/He Mammary gland carcinoma Mammary gland

2 - 40
HR/De Hrhr/? Mammary gland carcinoma Mammary gland

4.2 - 30
wild mice Mammary gland carcinoma Mammary gland

6.1
C3H/He Mammary gland tumor Mammary gland

99 - 100
DBA/2 Mammary gland tumor Mammary gland

77 - 77
A Mammary gland tumor Mammary gland

5 - 84
DD/He Mammary gland tumor Mammary gland

75 - 84
C3H Mammary gland tumor Mammary gland

high
DBA Mammary gland tumor Mammary gland

moderate - high
DD Mammary gland tumor Mammary gland

high
H Mammary gland tumor Mammary gland

observed - high
C3HeB/De Mammary gland tumor - mixed Mammary gland

0.6 - 4.9
C3H/J Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3
C3HeB/De Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

1.2 - 7.1
C3HeB/De Mesodermal cell/mesoblast sarcoma Uterus

3.0
C3Hf/He Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3
C3Hf/He Mesodermal cell/mesoblast sarcoma Uterus

2
C57BL/He Mesodermal cell/mesoblast sarcoma Uterus

1
DBA/2eBDe Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3.9
DBA/2eBDe Mesodermal cell/mesoblast sarcoma Uterus - Endometrium

2.0
HR/De Hrhr/? Mesodermal cell/mesoblast sarcoma Uterus

2.1 - 3.2
HR/De Hrhr/? Mesodermal cell/mesoblast sarcoma Mammary gland

1.6
wild mice Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

1.4 - 2.0
C3H Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed
C3Hf Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed
C57BL Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

0
(DED2F1 x DBA/2WyDi) Mesodermal cell/mesoblast sarcoma CNS - Meninges

observed
DBA/2eBDe Muscle - Smooth leiomyoma Uterus

1.3
BALB/c Myoepithelial cell myoepithelioma Salivary gland - Parotid

4
A Myoepithelial cell myoepithelioma Salivary gland - Parotid

4
C3HeB/De Myoepithelial cell myoepithelioma Myoepithelial cell

1.2
HR/De Hrhr/? Myoepithelial cell myoepithelioma Myoepithelial cell

1.6
C58 Myoepithelial cell myoepithelioma Salivary gland - Parotid

observed
C3H Ovary - Germ cell teratoma Ovary - Germ cell

observed
C3H/J Ovary - Germ cell teratoma Ovary - Germ cell

observed
C3HeB/De Ovary - Granulosa cell tumor Ovary - Granulosa cell

13 - 23
C57BL/He Ovary - Granulosa cell tumor Ovary - Granulosa cell

1
HR/De Hrhr/? Ovary - Granulosa cell tumor Ovary - Granulosa cell

2.1 - 4.8
wild mice Ovary - Granulosa cell tumor Ovary - Granulosa cell

2.8 - 6.1
C3HeB/De Ovary adenoma - tubular Ovary

14 - 25
HR/De Hrhr/? Ovary cystadenoma - papillary Ovary

1.6 - 2.1
C3HeB/De Ovary luteoma Ovary

0.6 - 2.0
C3HeB/De Ovary tumor Ovary

29 - 47
C3HeB/Fe Ovary tumor Ovary

22 - 64
RIII Ovary tumor Ovary

50 - 60
CE/Wy Ovary tumor Ovary

34
C3Hf/He Ovary tumor Ovary

6.0 - 8
CE Ovary tumor Ovary

34
C3HeB/FeJ Ovary tumor Ovary

64
RIII/J Ovary tumor Ovary

60
C3Hf/He PNS - Schwann cell myoblastoma - granular cell PNS - Schwann cell

1
C3H PNS - Schwann cell myoblastoma - granular cell PNS - Schwann cell

observed
(C3Hf x I)F1 Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell

high
(C3Hf x I)F1 Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell

high
HR/De Hrhr/? Pancreas - Islet of Langerhans tumor Pancreas - Islet of Langerhans

1.6
C57L Pituitary gland tumor Pituitary gland

3.5 - 33
C57BR/cd Pituitary gland tumor Pituitary gland

33
(L x A)F1 Pituitary gland tumor Pituitary gland

1
C57L/J Pituitary gland tumor Pituitary gland

33
C57BR/cdJ Pituitary gland tumor Pituitary gland

33
CE Pituitary gland tumor Pituitary gland

observed
C57BL/6 Pituitary gland tumor Pituitary gland

observed
DBA Skin - Melanocyte melanoma Skin - Melanocyte

very low
HR/De Hrhr Skin carcinoma Skin

3
HR/De Hrhr Skin papilloma Skin

9 - low
C3HeB/De Skin papilloma Skin

0.6
C3Hf/He Skin papilloma Skin

1
HR/De Hrhr/? Skin papilloma Skin

1.6 - 3.8
HR/De Hrhr/+ Skin papilloma Skin

low
C3HeB/De Skin squamous cell carcinoma Skin

0.6
C3Hf/He Skin squamous cell carcinoma Skin

1
C57BL/He Skin squamous cell carcinoma Skin

1
HR/De Hrhr/? Skin squamous cell carcinoma Skin

1.6 - 5.8
HR/De Hrhr Skin squamous cell carcinoma Skin

low
HR/De Hrhr/+ Skin squamous cell carcinoma Skin

low
129 Testis - Germ cell teratoma Testis - Germ cell

1
129 Testis - Germ cell teratoma
  • male gonadal ridge implantation
 Testis - Germ cell

82
wild mice Testis - Germ cell teratoma Testis - Germ cell

1.9
129.C3-KitlSl Testis - Germ cell teratoma Testis - Germ cell

10
H Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

observed
BALB/c Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

observed
C Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed
BALB/c Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed
RF Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed
H Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed
BALB/c Testis - Leydig cell (Interstitial cell) tumor
  • estrogen
 Testis - Leydig cell (Interstitial cell)

observed
A Testis - Leydig cell (Interstitial cell) tumor
  • estrogen
 Testis - Leydig cell (Interstitial cell)

observed
C3Hf/He Urinary bladder papilloma Urinary bladder

1
HR/De Hrhr/? Uterus adenocarcinoma Uterus

1.6
BALB/c Uterus adenocarcinoma Uterus

observed
(C3H x C57BL)F1 Uterus adenocarcinoma Uterus

observed
129P3/J Vulva papilloma Vulva

observed
129P3/J Vulva squamous cell carcinoma Vulva

observed
C3Hf/He (Unspecified organ) tumor (Unspecified organ)

3.0