Reference SummaryHeston WE, J Natl Cancer Inst 1960;24():425-435

Title	High incidence of spontaneous hepatomas and the increase of this incidence with urethan in C3H, C3Hf, and C3He male mice
Authors	Heston WE; Vlahakis G; Deringer MK
Journal	J Natl Cancer Inst
Volume	24
Issue
Year	1960
Pages	425-435
Abstract
Links	J:2433 – MGI References 14401531 – National Library of Medicine/PubMed

Models
Strain	Model Name	Treatment Agent(s)	Organ Affected	Frequency
C3HeB/De	Blood vessel hemangioendothelioma	urethane (ethyl carbamate)	Peritoneum - Mesentery	1.4
C3H/He	Liver hepatoma	urethane (ethyl carbamate)	Liver	79.5 - 92.6
C3H/He	Liver hepatoma		Liver	85.3
C3Hf/He	Liver hepatoma	urethane (ethyl carbamate)	Liver	90 - 94.6
C3Hf/He	Liver hepatoma		Liver	71.9
C3Hf/He	Liver hepatoma	Purina laboratory chow	Liver	57.4
C3HeB/De	Liver hepatoma	urethane (ethyl carbamate)	Liver	89 - 91.4
C3HeB/De	Liver hepatoma		Liver	78.5
C3H/He	Lung tumor	urethane (ethyl carbamate)	Lung	62.1 - 100
C3H/He	Lung tumor		Lung	7.8
C3Hf/He	Lung tumor	urethane (ethyl carbamate)	Lung	54.8 - 97.5
C3Hf/He	Lung tumor		Lung	10.4
C3Hf/He	Lung tumor	Purina laboratory chow	Lung	4.6
C3HeB/De	Lung tumor	urethane (ethyl carbamate)	Lung	57.5 - 100
C3HeB/De	Lung tumor		Lung	12.7
C3Hf/He	Skin papilloma	urethane (ethyl carbamate)	Skin	1.3
C3Hf/He	Skin squamous cell carcinoma	urethane (ethyl carbamate)	Skin	1.3
C3H/He	(Unspecified organ) reticulum cell neoplasm		(Unspecified organ)	1.0
C3Hf/He	(Unspecified organ) reticulum cell neoplasm	urethane (ethyl carbamate)	(Unspecified organ)	1.1

Models