Mouse Models of Human Cancer Database (MMHCdb)
MMHCdb is a comprehensive, expertly curated resource of diverse mouse models of human cancer.
We focus on:
- spontaneous and induced tumors in mice
- genetically defined mouse models of cancer (inbred, hybrid, mutant, and genetically engineered strains of mice)
- Patient Derived Xenograft (PDX) models
American Cancer Society Facts & Figures 2023 | Mouse Models | |||||
---|---|---|---|---|---|---|
Cancer Site | Mortality Rank | Estimated deaths USA | Mutant Strains | Other Strains | All Strains | PDX Models |
Lung & other respiratory | [1] | 132,330 | 56 | 116 | 172 | 79 |
Lymphohematopoietic | [2] | 57,380 | 138 | 35 | 173 | 30 |
Colon & other intestine | [3] | 56,490 | 83 | 4 | 87 | 81 |
Pancreas | [4] | 50,550 | 35 | 2 | 37 | 15 |
Breast | [5] | 43,700 | 129 | 31 | 160 | 46 |
Prostate | [6] | 34,700 | 55 | 0 | 55 | 2 |
Liver & bile duct | [7] | 29,380 | 25 | 24 | 49 | 2 |
Brain & other nervous system | [8] | 18,990 | 42 | 0 | 42 | 25 |
Uterus & cervix | [9] | 17,340 | 6 | 3 | 9 | 6 |
Urinary bladder | [10] | 16,710 | 7 | 1 | 8 | 27 |
Esophagus | [11] | 16,120 | 0 | 8 | 8 | 0 |
Kidney & renal pelvis | [12] | 14,890 | 5 | 0 | 5 | 8 |
Ovary | [13] | 13,270 | 9 | 0 | 9 | 12 |
Skin | [14] | 12,470 | 24 | 13 | 37 | 20 |
Oral cavity & pharynx | [15] | 11,580 | 3 | 3 | 6 | 3 |
Stomach | [16] | 11,130 | 17 | 7 | 24 | 1 |
Soft tissue including heart | [17] | 5,140 | 27 | 20 | 47 | 28 |
Gallbladder & other biliary | [18] | 4,510 | 2 | 0 | 2 | 0 |
Endocrine system | [19] | 3,240 | 65 | 2 | 67 | 1 |
Bones & joints | [20] | 2,140 | 5 | 0 | 5 | 11 |