Mouse Models of Human Cancer Database (MMHCdb)
MMHCdb is a comprehensive, expertly curated resource of diverse mouse models of human cancer.
We focus on:
- spontaneous and induced tumors in mice
- genetically defined mouse models of cancer (inbred, hybrid, mutant, and genetically engineered strains of mice)
- Patient Derived Xenograft (PDX) models
| American Cancer Society Facts & Figures 2022 | Mouse Models | |||||
|---|---|---|---|---|---|---|
| Cancer Site | Mortality Rank | Estimated deaths USA | Mutant Strains | Other Strains | All Strains | PDX Models |
| Lung & other respiratory | [1] | 135,360 | 56 | 116 | 172 | 79 |
| Lymphohematopoietic | [2] | 57,810 | 138 | 35 | 173 | 30 |
| Colon & other intestine | [3] | 56,210 | 81 | 4 | 85 | 81 |
| Pancreas | [4] | 49,830 | 35 | 1 | 36 | 15 |
| Breast | [5] | 43,780 | 129 | 31 | 160 | 46 |
| Prostate | [6] | 34,500 | 55 | 0 | 55 | 2 |
| Liver & bile duct | [7] | 30,520 | 25 | 24 | 49 | 2 |
| Brain & other nervous system | [8] | 18,280 | 42 | 0 | 42 | 25 |
| Urinary bladder | [9] | 17,100 | 7 | 1 | 8 | 27 |
| Uterus & cervix | [10] | 16,830 | 6 | 3 | 9 | 6 |
| Esophagus | [11] | 16,410 | 0 | 8 | 8 | 0 |
| Kidney & renal pelvis | [12] | 13,920 | 5 | 0 | 5 | 8 |
| Ovary | [13] | 12,810 | 9 | 0 | 9 | 12 |
| Skin | [14] | 11,990 | 24 | 13 | 37 | 20 |
| Oral cavity & pharynx | [15] | 11,230 | 3 | 3 | 6 | 3 |
| Stomach | [16] | 11,090 | 17 | 7 | 24 | 1 |
| Soft tissue including heart | [17] | 5,130 | 27 | 20 | 47 | 28 |
| Gallbladder & other biliary | [18] | 4,400 | 2 | 0 | 2 | 0 |
| Endocrine system | [19] | 3,330 | 64 | 2 | 66 | 1 |
| Bones & joints | [20] | 2,100 | 5 | 0 | 5 | 11 |