Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2020-01-26
MTB 3.0
 
HelpHelp and Documentation Tumor Summary  

Tumor Name Bone
osteosarcoma
Treatment Type None (spontaneous)
Tumor Synonym osteosarcoma
 
Strain
BALB/cJ-Trp53tm2.1Tyj/+
Strain Type:
targeted mutation (knock-in)
General Note:
Heterozygous mice. The genetic background of these mice was predominantly BALB/cJ as this cohort was generated from crossing congenic strains. There was also some contribution from 129S4/SvJae and possibly some other strain(s).
Strain Synonym p53R172H/+

MTB ID Organ Affected Treatment Type
Agents
Strain Sex Reproductive Status Infection Status Frequency Age Of
Onset
Age Of
Detection
Additional
Information
Reference
MTB:93090 Bone None (spontaneous) Unspecified reproductive status not specified   19%
(6 of 32 mice)
      J:241797