Model DetailsIntestine - Large Intestine adenoma

Model Name

Intestine - Large Intestine adenoma

Strain

C57BL/6-Apctm2Rak Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy Tg(tetO-Kras*G12D)#Rdp Tg(Vil1-cre/ERT2)23Syr Trp53tm1Brn/+

Tumor Inducing Agent(s)

Genetic Modification : doxycycline  •  4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles)

Tumor Synonym

CRC adenoma

Strain Synonyms

C57BL/6-Apctm2Rak Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy Tg(tetO-Kras*G12D)#Rdp Tg(Vil-cre/ERT2)23Syr Trp53tm1Brn/+  •  IKA(P/+)
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Intestine - Large Intestine Unspecified

64%

 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Boutin AT, Genes Dev 2017 Feb 15;31(4):370-382