Model DetailsSkin - Melanocyte melanoma - amelanotic

Model Name

Skin - Melanocyte melanoma - amelanotic

Strain

[not specified]-Cdkn2atm2.1Nesh/+ Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn/+

Tumor Inducing Agent(s)

Genetic Modification : 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles)

Tumor Synonyms

'amelanotic' melanoma  •  melanoma

Strain Synonyms

TKp16L/+p53L/+  •  Tyr-CRE-ERT2 Lox-Stop-Lox-KRasG12D p16L/+ p53L/+  •  Tyr-CRE-ERT2 + KRasLSL/+ p16L/+p53L/+
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Skin - Melanocyte Unspecified

43%

(3 of 7 mice)
>52 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Monahan KB, Oncogene 2010 Aug 9;():
(Unspecified organ) Unspecified

0%

(0 of 3 mice)
 
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Monahan KB, Oncogene 2010 Aug 9;():