Model DetailsSkin - Melanocyte melanoma

Model Name

Skin - Melanocyte melanoma

Strain

[not specified]-Braftm1Mmcm/+ Fbxo4tm1.1Jadi Tg(Tyr-cre/ERT2)13Bos

Tumor Inducing Agent(s)

Genetic Modification : 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles)

Tumor Synonym

skin melanocyte melanoma

Strain Synonym

BrafCA/+; CreER+/0; Fbxo4-/-
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Skin - Melanocyte Unspecified

70%

(7 of 10 mice)
10 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    6 weeks

Lee EK, Mol Cell Biol 2013 Nov;33(22):4422-33