Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Tumor Summary  

Tumor Name Spleen
hyperplasia
Treatment Type None (spontaneous)
Tumor Synonym spleen hyperplasia
 
Strain
KK/HlJ
Strain Type:
inbred
General Note:
Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
Strain Synonyms KK/J  •  KK/HiJ

MTB ID Organ Affected Treatment Type
Agents
Strain Sex Reproductive Status Infection Status Frequency Age Of
Onset
Age Of
Detection
Additional
Information
Reference
MTB:50802 Spleen None (spontaneous) Female reproductive status not specified   observed   586 days Additional Notes J:122261
MTB:76845 Spleen None (spontaneous) Female reproductive status not specified   44.44%
(4 of 9 mice)
  6 months   J:227536
MTB:76846 Spleen None (spontaneous) Male reproductive status not specified   12.5%
(1 of 8 mice)
  6 months   J:227536
MTB:76847 Spleen None (spontaneous) Mixed Population reproductive status not specified   29.41%
(5 of 17 mice)
  6 months Additional Notes J:227536
MTB:76848 Spleen None (spontaneous) Female reproductive status not specified   0%
(0 of 15 mice)
  12 months   J:227536
MTB:76849 Spleen None (spontaneous) Male reproductive status not specified   0%
(0 of 12 mice)
  12 months   J:227536
MTB:76850 Spleen None (spontaneous) Mixed Population reproductive status not specified   0%
(0 of 27 mice)
  12 months   J:227536
MTB:77048 Spleen None (spontaneous) Female reproductive status not specified   14.29%
(1 of 7 mice)
  20 months   J:227536
MTB:77049 Spleen None (spontaneous) Male reproductive status not specified   0%
(0 of 7 mice)
  20 months   J:227536
MTB:77050 Spleen None (spontaneous) Mixed Population reproductive status not specified   7.14%
(1 of 14 mice)
  20 months Additional Notes J:227536
MTB:77051 Spleen None (spontaneous) Female reproductive status not specified   75%
(3 of 4 mice)
436 days 857 days Additional Notes J:227536
MTB:77052 Spleen None (spontaneous) Male reproductive status not specified   0%
(0 of 3 mice)
436 days 857 days Additional Notes J:227536
MTB:77053 Spleen None (spontaneous) Mixed Population reproductive status not specified   42.86%
(3 of 7 mice)
436 days 857 days Additional Notes J:227536
MTB:77166 Spleen None (spontaneous) Female reproductive status not specified   22.86%
(8 of 35 mice)
  486 days Additional Notes J:227536
MTB:77167 Spleen None (spontaneous) Male reproductive status not specified   3.33%
(1 of 30 mice)
  486 days Additional Notes J:227536
MTB:77168 Spleen None (spontaneous) Mixed Population reproductive status not specified   13.85%
(9 of 65 mice)
  486 days Additional Notes J:227536