Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2020-01-26
MTB 3.0
 
HelpHelp and Documentation Tumor Summary  

Tumor Name Intestine - Large Intestine - Colon
adenocarcinoma
Treatment Type None (spontaneous)
Tumor Synonyms colonic adenocarcinoma  •  colon cancer
 
Strain
B6;129-B2mtm1Unc Il2tm1Hor
Strain Type:
targeted mutation (knockout)
General Note:
Mice were homozygous for both B2mtm1Unc and Il2tm1Hor. The genetic background of these mice is a mixture of C57BL/6, 129P2/OlaHsd, and some other unspecified substrain of "129/Sv".
Strain Synonyms β2mnull x IL-2null  •  IL-2NULL X β2MNULL  •  interleukin 2- and β2-microglobulin-deficient  •  IL-2null X β2mnull  •  B2m-/- x IL2-/-

MTB ID Organ Affected Treatment Type
Agents
Strain Sex Reproductive Status Infection Status Frequency Age Of
Onset
Age Of
Detection
Additional
Information
Reference
MTB:24732 Intestine - Large Intestine - Colon None (spontaneous) Unspecified reproductive status not specified   observed     Genetics

Additional Notes
J:71656