Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-17
MTB 3.0
 
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6 matching items displayed.
Strain Name Strain Type Strain Notes
B6.Cg-Trp53tm1Sia targeted mutation (knockout) Homozygous mice. These mice had been backcrossed onto C57BL/6CrSlc. The targeted mutation was generated in (C57BL/6NCrlj x CBA/JNCrlj)F1 ES cells.
C3.Cg-Trp53tm1Sia targeted mutation (knockout) Homozygous mice. These mice had been backcrossed onto C3H/HeMsNrs. The targeted mutation was generated in (C57BL/6NCrlj x CBA/JNCrlj)F1 ES cells.
[not specified] +/+ : STOCK Irf1tm1Mak Trp53tm1Sia chimeric &
targeted mutation (knockout)
Chimeras generated by aggregation of cells from homozygous double-KO (Irf1tm1Mak, Trp53tm1Sia) and wild-type embryos of unspecified genetic background. They were used at the eight-cell stage. Cells were mixed 1:1.
[not specified]-Irf1tm1Mak Trp53tm1Sia targeted mutation (knockout) Mice homozygous for targeted mutations of the Irf1 and Trp53 genes (the genetic background was not specified).
[not specified]-Trp53tm1Sia targeted mutation (knockout) Mice homozygous for a targeted disruption of the Trp53 gene (the genetic background was not specified).
[not specified]-Trp53tm1Sia : STOCK Irf1tm1Mak Trp53tm1Sia chimeric &
targeted mutation (knockout)
Chimeras generated by aggregation of cells from homozygous double-KO (Irf1tm1Mak, Trp53tm1Sia) and homozygous Trp53tm1Sia single-KO embryos. They were used at the eight-cell stage. Cells were mixed 1:1.