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Last Database Update
2019-11-10
MTB 3.0
 
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5 matching items displayed.
Strain Name Strain Type Strain Notes
B6;129-Nf1tm1Fcr +/+ Trp53tm1Tyj targeted mutation (knockout) Mice heterozygous for gene-targeted mutant alleles of Nf1 and Trp53 on opposite chromosomes 11 ("trans" heterozygotes). The genetic background was a mix of C57BL/6 and 129/Sv (a mixture of 129S2/SvPas, 129S4/SvJae, and 129S6/SvEv).
B6;129-Nf1tm1Fcr Trp53tm1Tyj/+ + targeted mutation (knockout) Mice heterozygous for gene-targeted mutant alleles of Nf1 and Trp53 on the same chromosome 11 ("cis" heterozygotes). The genetic background was a mix of C57BL/6 and 129/Sv (a mixture of 129S2/SvPas, 129S4/SvJae, and 129S6/SvEv).
B6;129-Nf1tm1Fcr/+ Trp53tm1Tyj targeted mutation (knockout) Mice heterozygous for a gene-targeted mutant allele of Nf1 and homozygous for a disrupted Trp53 gene. The genetic background was a mix of C57BL/6 and 129/Sv (a mixture of 129S2/SvPas, 129S4/SvJae, and 129S6/SvEv).
[not specified]-Nf1tm1Fcr/+ targeted mutation (knockout) Mice heterozygous for a targeted mutation of Nf1. The genetic background of these animals was not specified but included some 129S/SvEv-Gpi1c. Chimeric males were bred to either C57BL/6J or 129X1/SvJ females.
[not specified]-Nf1tm1Fcr/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice were not specified, but involved contributions from 129S6/SvEvTac, possibly C57BL/6, and possibly other strains.