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Strain Name Strain Type Strain Notes
B6;129S7-Trp53tm1Ldo/+ targeted mutation (knock-in) Mice heterozygous for a Trp53 mutation involving an Arg245Trp substitution and a deleted 20 kb of sequence that included exons 1-6 and a large undefined upstream region. Background was mix of C57BL/6 and 129S7/SvEvBrd-Hprt+.