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Last Database Update
2019-11-10
MTB 3.0
 
HelpHelp and Documentation Strain Search Results  
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264 matching items displayed.
Strain Name Strain Type Strain Notes
129/Sv;B6-Cdkn2atm1Rdp Gli1tm2Alj/+ Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, Gli1, homozygous Cdkn2a mutant mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed 129/Sv and C57BL/6 background with possible contributions from FVB/N, C57BL/6J, SJL, 129S6/SvEvTac, and/or 129S4/SvJae.
129/Sv;B6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krastm4Tyj, Ptf1atm1.1(cre)Cvw mice on a mixed 129/Sv and C57BL/6 background with possible contributions from 129X1/SvJ, 129S1/Sv, and/or 129S4/SvJae.
129/Sv;B6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Shhtm2Amc targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krastm4Tyj, Ptf1atm1.1(cre)Cvw, homozygous Shhtm2Amc mice on a mixed 129/Sv and C57BL/6 background with possible contributions from 129X1/SvJ, 129S1/Sv, and/or 129S4/SvJae.
129/Sv;B6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Shhtm2Amc Trp53tm1Brn/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Ptf1a, Trp53, homozygous Shh mutant mice on a mixed 129/Sv and C57BL/6 background with possible contributions from 129P2/OlaHsd, 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
129/Sv;B6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Trp53tm1Brn/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krastm4Tyj, Ptf1atm1.1(cre)Cvw, Trp53tm1Brn mice on a mixed 129/Sv and C57BL/6 background with possible contributions from 129P2/OlaHsd, 129X1/SvJ, 129S1/Sv, and/or 129S4/SvJae.
129/Sv;B6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous, transgenic mice on a mixed 129/SvJae, C57BL/6 background with possible contributions from 129S4/SvJae and FVB/N.
129/Sv;B6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous, transgenic mice on a mixed 129/SvJae, C57BL/6 background with possible contributions from 129S4/SvJae and FVB/N.
B6.129S4-Krastm4Tyj/J targeted mutation (conditional) Congenic mice heterozygous for the Krastm4Tyj allele which was generated in 129S4/SvJae ES cells. Mice were purchased from the Jackson Laboratory.
B6;129-Atg5tm1Myok Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Homozygous Atg5, heterozygous Kras mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, and/or 129S/SvEv-Gpi1c.
B6;129-Atg5tm1Myok Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Brn targeted mutation (conditional) &
transgenic
Homozygous Trp53, Atg5, het Kras mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, 129P2OlaHsd, and 129S/SvEv-Gpi1c.
B6;129-Atg7tm1Tchi Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Homozygous Atg7, heterozygous Kras mutant mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, C57BL/6NCrlj, and/or CBA/JNCrlj.
B6;129-Atg7tm1Tchi Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Brn targeted mutation (conditional) &
transgenic
Homozygous Trp53, Atg7, heterozygous Kras mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, 129P2OlaHsd, C57BL/6NCrlj, and/or CBA/JNCrlj.
B6;129-Atmtm2.1Fwa Krastm4Tyj/+ targeted mutation (conditional) Heterozygous Kras, homozygous Atm mice on a mixed C57BL/6, 129/Sv (unspecified strain) background with contribution from 129S4/SvJae and 129S6/SvEvTac from the parental ES cells.
B6;129-Atmtm2.1Fwa Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Heterozygous Kras, homozygous Atm, Trp53 mice on a mixed C57BL/6, 129/Sv (unspecified strain) background with contribution from 129S4/SvJae, 129P2/OlaHsd, and 129S6/SvEvTac from the parental ES cells.
B6;129-Brca1tm1Thl Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Thl/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was reported to be mixed 129 x B6. The 129 included at least some 129S4/SvJae. There was also likely some contribution from FVB/N and possibly some other strain(s).
B6;129-Brca1tm1Thl Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm3Tyj/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was reported to be mixed 129 x B6. The 129 included at least some 129S4/SvJae. There was also likely some contribution from FVB/N and possibly some other strain(s).
B6;129-Ctnnb1tm1Mmt/+ Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze Krastm4Tyj/+ Prom1tm1(cre/ERT2)Gilb/+ targeted mutation (conditional) &
targeted mutation (knock-in)
The genetic background of these mice was mostly B6 (C57BL/6, C57BL/6J, & C57BL/6NCrl) and 129 (129S4/SvJaeSor, 129X1/SvJ, & substrain unspecified) with possible other strain(s) involved.
B6;129-Epas1tm1.1Mcs/+ Krastm4Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout)
Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129" (substrain not specified but included at least some 129X1/SvJ).
B6;129-Epas1tm1Mcs/Epas1tm1.1Mcs Krastm4Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout)
Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129" (substrain not specified but included at least some 129X1/SvJ).
B6;129-Gt(ROSA)26Sortm2(CAG-EGFP)Blh/Gt(ROSA)26Sor Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ Trp53tm5Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous mice on a mixed C57BL/6, 129 background. The 129 contribution could be from 129S4/SvJaeSor, 129S6/SvEvTac, and/or 129S4/SvJae.
B6;129-Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze Krastm4Tyj/+ Prom1tm1(cre/ERT2)Gilb/+ targeted mutation (conditional) &
targeted mutation (knock-in)
The genetic background of these mice was mixed B6 (C57BL/6, C57BL/6J, & C57BL/6NCrl) & 129 (129S4/SvJaeSor, 129S6/SvEvTac, & substrain unspecified).
B6;129-Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze Krastm4Tyj/+ Prom1tm1(cre/ERT2)Gilb/+ Trp53tm1Brn targeted mutation (conditional) &
targeted mutation (knock-in)
The genetic background of these mice was mixed B6 (C57BL/6, C57BL/6J, C57BL/6N, & C57BL/6NCrl) & 129 (129P2/OlaHsd, 129S4/SvJaeSor, 129S6/SvEvTac, & substrain unspecified).
B6;129-Hspa5tm1Alee/+ Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53, Hspa5 mutant mice also carrying the transgene on a mixed C57BL/6, 129 (substrains include 129/Sv & an unspecified 129 substrain) background with possible contributions from CBA, 129P2/OlaHsd, and 129S4/SvJae.
B6;129-Hspa5tm1Alee/+ Krastm4Tyj/+ Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53, Hspa5 mutant mice on a mixed C57BL/6, 129 (substrains include 129/Sv & an unspecified 129 substrain) background with possible contributions from CBA, 129P2/OlaHsd, and 129S4/SvJae.
B6;129-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous Kras mice on a mixed C57BL/6, 129/Sv (unspecified strain) background with contribution from 129S4/SvJae from the parental ES cells.
B6;129-Krastm4Tyj/+ Ptch1tm1Mps/+ targeted mutation (knockout) Heterozygous Ptch1, Kras mutant mice on a mixed C57BL/6, 129 background. 129 contributions were from at least 129X1/SvJ, 129S1/Sv, 129S4/SvJae, 129/SvJ, and 129/Ola.
B6;129-Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ Trp53tm5Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous mice on a mixed C57BL/6, 129 background. The 129 contribution could be from 129S4/SvJaeSor, 129S6/SvEvTac, and/or 129S4/SvJae.
B6;129-Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice also carrying the Tg(KRT5-cre/PGR)1Der transgene on a mixed C57BL/6 and "129/Sv" genetic background.
B6;129-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, C57BL/6NCrlj, and/or CBA/JNCrlj.
B6;129-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras mutant mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, and/or 129S/SvEv-Gpi1c.
B6;129-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Brn targeted mutation (conditional) &
transgenic
Homozygous Trp53, heterozygous Kras mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 and "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, 129P2OlaHsd, C57BL/6NCrlj, and/or CBA/JNCrlj.
B6;129-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Brn targeted mutation (conditional) &
transgenic
Homozygous Trp53, heterozygous Kras mutant mice also carrying the Tg(Pdx1-cre)6Tuv transgene on a mixed C57BL/6 & "129Sv1" background with possible contributions from FVB/N, 129S4/SvJae, 129P2OlaHsd, and/or 129S/SvEv-Gpi1c.
B6;129-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm3Tyj/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was reported to be mixed 129 x B6. The 129 included at least some 129S4/SvJae. There was also likely some contribution from FVB/N and possibly some other strain(s).
B6;129-Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mutant mice also carrying the transgene on a mixed C57BL/6, 129 (substrains include 129/Sv & an unspecified 129 substrain) background with possible contributions from CBA, 129P2/OlaHsd, and 129S4/SvJae.
B6;129-Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Heterozygous Kras, homozygous Trp53 mice on a mixed C57BL/6, 129/Sv (unspecified strain) background with contribution from 129S4/SvJae and 129P2/OlaHsd from the parental ES cells.
B6;129-Krastm4Tyj/+ Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mutant mice on a mixed C57BL/6, 129 (substrains include 129/Sv & an unspecified 129 substrain) background with possible contributions from CBA, 129P2/OlaHsd. and 129S4/SvJae from the parental ES Cells.
B6;129/Sv-Gt(ROSA)26Sor Krastm4Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous transgenic mice on a mixed 129/Sv, C57BL/6J background with possible contributions from 129S4/SvJaeSor and 129S4/SvJae.
B6;129/Sv-Gt(ROSA)26Sortm2(cre/ERT2)Brn Krastm4Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous transgenic mice on a mixed 129/Sv, C57BL/6J background with possible contributions from 129S4/SvJaeSor and 129S4/SvJae.
B6;129/Sv-Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor Krastm4Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous transgenic mice on a mixed 129/Sv, C57BL/6J background with possible contributions from 129S4/SvJaeSor and 129S4/SvJae. Mice contained one copy of each ROSA26 allele.
B6;129S-Atrtm1Bal/+ Krastm4Tyj/+ Ndor1Tg(UBC-cre/ERT2)1Ejb/? targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice were heterozygous for the knock-in and knock-out alleles and carried the transgene. The genetic background of these mice was a mixture of C57BL/6 and 129S (including at least 129S/SvEv, 129S4/SvJae, and 129S/Sv).
B6;129S-Atrtm1Bal/+ Krastm4Tyj/+ Ndor1Tg(UBC-cre/ERT2)1Ejb/? Trp53tm1Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice were heterozygous for the knock-in and both knock-out alleles and carried the transgene. The genetic background of these mice was a mixture of C57BL/6 and 129S (including at least 129S/SvEv, 129S4/SvJae, 129S2/SvPas, and 129S/Sv).
B6;129S-Krastm4Tyj/+ Ndor1Tg(UBC-cre/ERT2)1Ejb/? targeted mutation (conditional) &
transgenic
Mice were heterozygous for the knock-in allele and carried the transgene. The genetic background of these mice was a mixture of C57BL/6 and 129S (including at least 129S/SvEv and 129S4/SvJae).
B6;129S-Krastm4Tyj/+ Ndor1Tg(UBC-cre/ERT2)1Ejb/? Trp53tm1Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice were heterozygous for the knock-in and knock-out alleles and carried the transgene. The genetic background of these mice was a mixture of C57BL/6 and 129S (including at least 129S/SvEv, 129S4/SvJae, and 129S2/SvPas).
B6;129S-Krastm4Tyj/+ Tg(Mx1-cre)1Cgn targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on a (C57BL/6 x 129S4/SvJae)F1 background with contribution from CBA/J and 129S4/SvJae.
B6;129S/SvEv-Agertm1.1Arnd Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Ager, heterozygous Kras, Tg(Pdx1-cre)6Tuv transgenic mice on a mixed C57BL/6, 129S background. The 129S/SvEv substrain was not detailed. There are also possible contributions from 129P2/OlaHsd and FVB/N.
B6;129S1-Krastm4Tyj/+ Trp53tm2Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on a mixed C57BL/6,129S1/Sv background with contribution from 129S4/SvJae and FVB/N.
B6;129S4-Krastm4Tyj/+ Snai2tm2Grid Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Compound mutant mice on a mixed 129/SvJae and C57BL/6J background with possible contribution from 129S1/Sv, 129S4/SvJae, and FVB/N.
B6;129S4-Krastm4Tyj/+ Snai2tm2Grid/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Compound mutant mice on a mixed 129/SvJae and C57BL/6J background with possible contribution from 129S1/Sv, 129S4/SvJae, and FVB/N.
B6;129S4-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Compound mutant mice on a mixed 129/SvJae and C57BL/6J background with possible contribution from 129S1/Sv, 129S4/SvJae, and FVB/N.
B6;129S6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras mutant mice also carrying the transgene on a mixed C57BL/6, 129S6/SvEv background with contribution from 129S4/SvJae and FVB/N.
B6;129S6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mutant mice also carrying the transgene on a mixed C57BL/6, 129S6/SvEv background with contribution from 129S4/SvJae and FVB/N.
B6;129S6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Trp53 mutant mice also carrying the transgene on a mixed C57BL/6, 129S6/SvEv background with contribution from 129S4/SvJae and FVB/N.
B6;129X1-Krastm4Tyj/+ targeted mutation (conditional) The genetic background of these mice is a mixture of C57BL/6 and 129X1/SvJ. Mice were heterozygous for the Krastm4Tyj targeted mutation.
B6;129X1-Krastm4Tyj/+ Rb1tm3Tyj targeted mutation (conditional) The genetic background of these mice is a mixture of C57BL/6 and 129X1/SvJ. Mice were heterozygous for the Krastm4Tyj and homozygous for the Rb1tm3Tyj targeted mutations.
B6;129X1-Krastm4Tyj/+ Rbl2tm2Tyj targeted mutation (conditional) The genetic background of these mice is a mixture of C57BL/6 and 129X1/SvJ. Mice were heterozygous for the Krastm4Tyj and homozygous for the Rbl2tm2Tyj targeted mutations.
B6;CD-1-Gt(ROSA)26Sortm1(EYFP)Cos Krastm4Tyj/+ Ptentm1Hwu Tg(Sox9-cre/ERT2)1Msan gene trapped &
targeted mutation (conditional) &
transgenic
Homozygous Pten heterozygous Kras mice carrying both transgenes on a mixed C57BL/6, CD-1 background with contribution from BALB/c, 129S6/SvEvTac, 129S4/SvJae and 129X1/SvJ.
B6;CD-1-Gt(ROSA)26Sortm1(EYFP)Cos Krastm4Tyj/+ Ptentm1Hwu/+ Tg(Sox9-cre/ERT2)1Msan gene trapped &
targeted mutation (conditional) &
transgenic
Heterozygous Pten, Kras mice carrying both transgenes on a mixed C57BL/6, CD-1 background with contribution from BALB/c, 129S6/SvEvTac, 129S4/SvJae and 129X1/SvJ.
B6;FVB-Krastm4Tyj/+ Shhtm2(cre/ERT2)Cjt Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was a mix of mostly C57BL/6J and FVB/N with contributions from 129S6/SvEvTac, 129S4/SvJae, and 129P2/OlaHsd.
C57BL/6-Albtm1(cre/ERT2)Mtz/+ Krastm4Tyj/+ Ptentm2Mak targeted mutation (conditional) &
targeted mutation (knock-in)
Compound mutant mice. The genetic background of this cohort was stated to be C57BL/6. It may have also contained some 129P2/OlaHsd, 129S2/SvPas, 129S4/SvJae, and/or other strain(s).
C57BL/6-Amhr2tm3(cre)Bhr/+ Ctnnb1tm1Mmt/+ Krastm4Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Ctnnb1tm1Mmt, Krastm4Tyj, and cre-expressing mice on a C57BL/6 background with possible contributions from 129S7/SvEvBrd-Hprt+, 129X1/SvJ, and/or 129S4/SvJae.
C57BL/6-Amhr2tm3(cre)Bhr/+ Krastm4Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj and cre-expressing mice on a C57BL/6 background with possible contributions from 129S7/SvEvBrd-Hprt+ and/or 129S4/SvJae.
C57BL/6-Apctm1Mmt/+ Fbxw7tm1Kei Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Kras, Fbxw7 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, and DBA/2.
C57BL/6-Apctm1Mmt/+ Fbxw7tm1Kei Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr Tgfbr2tm1Hlm targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Kras, homozygous Tgfbr2, Fbxw7 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, 129S6/SvEvTac, and DBA/2.
C57BL/6-Apctm1Mmt/+ Fbxw7tm1Kei Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr Tgfbr2tm1Hlm Trp53tm3Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Trp53, Kras, homozygous Tgfbr2, Fbxw7 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, 129S6/SvEvTac, and DBA/2.
C57BL/6-Apctm1Mmt/+ Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Kras mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, and DBA/2.
C57BL/6-Apctm1Mmt/+ Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr Tgfbr2tm1Hlm targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Kras, homozygous Tgfbr2 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, and DBA/2.
C57BL/6-Apctm1Mmt/+ Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr Tgfbr2tm1Hlm Trp53tm3Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Kras, Trp53, homozygous Tgfbr2 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, 129S6/SvEvTac, and DBA/2.
C57BL/6-Apctm1Mmt/+ Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr Trp53tm3Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Apc, Kras, Trp53 mutant mice carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, and DBA/2.
C57BL/6-Apctm2.1Rak/+Krastm4Tyj/+ Tg(Fabp1-cre)1Jig targeted mutation (conditional) &
transgenic
Heterozygous Apc, Kras mice carrying the transgene on a primarily C57BL/6 background (80-95%) with contribution from FVB/N and 129S4/SvJae.
C57BL/6-Cdh1tm2Kem Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn/? targeted mutation (conditional) &
transgenic
Homozygous Cdh1, heterozygous Kras mutant mice, also transgenic and on a C57BL/6 background with possible contributions from 129X1/SvJ, 129S1/Sv, 129S4/SvJae, and/or DBA/2.
C57BL/6-Ctnnb1tm1Mmt/+ Krastm4Tyj/+ Tg(CYP19A1-cre)1Jri targeted mutation (conditional) &
transgenic
Heterozygous Ctnnb1tm1Mmt, Krastm4Tyj, transgenic mice on a C57BL/6 background with possible contributions from 129X1/SvJ and 129S4/SvJae and possibly some other strain(s).
C57BL/6-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous Kras mutant mice on a C57BL/6 background with contribution from 129X1/SvJ and 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu/+ Ptentm2Mak targeted mutation (conditional) &
targeted mutation (knock-in)
Compound mutant mice. The genetic background of this cohort was stated to be C57BL/6. It may have also contained some 129P2/OlaHsd, 129S4/SvJae, 129S6/SvEvTac, and/or other strain(s).
C57BL/6-Krastm4Tyj/+ Nfil3tm1Look targeted mutation (conditional) &
targeted mutation (knockout)
Heterozygous Kras, homozygous Nfil3 mutant mice on a C57BL/6 background with contribution from 129X1/SvJ and 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of this cohort was stated to be C57BL/6. It may have also contained some DBA, 129P2/OlaHsd, 129S4/SvJae, and/or other strain(s).
C57BL/6-Krastm4Tyj/+ Ptentm2Mak/+ Speer6-ps1Tg(Alb-cre)21Mgn/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of this cohort was stated to be C57BL/6. It may have also contained some DBA, 129P2/OlaHsd, 129S4/SvJae, and/or other strain(s).
C57BL/6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Ptf1a mice on a >95% C57BL/6 background. Mice may contain additional contributions from at least 129S4/SvJae, 129X1, and/or 129S1/Sv.
C57BL/6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Tgfbr2tm1.2Hlm targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Ptf1a, homozygous Tgfbr2 mice on a >95% C57BL/6 background. Mice may have contained additional contributions from at least 129S4/SvJae, 129X1, 129S1/Sv, and/or 129S6/SvEvTac.
C57BL/6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Trp53tm1Brn/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Trp53, Ptf1a mice. Mice were stated as being on a "C57Bl6/CR" background but may have also carried contributions from 129X1/SvJ, 129S1/Sv, 129S4/Jae, and 129P2/OlaHsd.
C57BL/6-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Trp53tm2Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Trp53, Ptf1a mice. Mice were stated as being on a "C57Bl6/CR" genetic background but may have also carried contributions from 129X1/SvJ, 129S1/Sv, 129S4/Jae, and 129S2/SvPas.
C57BL/6-Krastm4Tyj/+ Scgb1a1tm1.1(cre)Fjd targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krastm4Tyj, homozygous Scgb1a1tm1.1(cre)Fjd mice on a predominantly C57BL/6 background with possible contributions from 129S4/SvJae, 129X1/SvJ, and/or 129S1/Sv.
C57BL/6-Krastm4Tyj/+ Shhtm2(cre/ERT2)Cjt targeted mutation (conditional) &
transgenic
Heterozygous mice carrying the transgene on a C57BL/6J background with contributions from 129S6/SvEvTac and 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Smad4tm2.1Cxd Tg(Krt1-15-cre/PGR)22Cot targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Smad4 mice carrying the Tg(Krt1-15-cre/PGR)22Cot transgene on a C57BL/6 background with possible contributions from C57BL/6J, SJL/J, 129S6/SvEvTac, and/or 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of this cohort was stated to be C57BL/6. It may have also contained some DBA, 129S4/SvJae, and/or other strain(s).
C57BL/6-Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn/? targeted mutation (conditional) &
transgenic
Heterozygous Kras and transgenic mice on a C57BL/6 background with possible contributions from 129S4/SvJae and/or DBA/2.
C57BL/6-Krastm4Tyj/+ Tg(Fabp1-cre)1Jig targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on a primarily C57BL/6 background (80-95%) with contribution from FVB/N and 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Tg(Krt1-15-cre/PGR)22Cot targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the Tg(Krt1-15-cre/PGR)22Cot transgene on a C57BL/6 background with possible contributions from C57BL/6J, SJL/J, 129S6/SvEvTac, and/or 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras, Tg(Pdx1-cre)6Tuv transgenic mice on a C57BL/6 background with possible contribution from FVB/N and 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on a primarily C57BL/6 background (80-95%) with contribution from FVB/N and 129S4/SvJae.
C57BL/6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, Trp53 mice also carrying the transgene on a C57BL/6 background with contribution from 129S4/SJae, FVB/N, 129X1/SvJ, and 129S1/Sv.
C57BL/6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ Zeb1tm2Yhi/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, Trp53, Zeb1 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S4/SJae, FVB/N, 129X1/SvJ, and 129S1/Sv.
C57BL/6-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm3Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on a primarily C57BL/6 background (80-95%) with contribution from FVB/N and 129S4/SvJae.
C57BL/6J-Apctm2Rak/+ Krastm4Tyj/+ Tg(Car1-cre)5Flt targeted mutation (conditional) &
transgenic
Heterozygous Apc, Kras mice carrying the transgene on a C57BL/6J background with contribution from 129Sv, SJL and 129S4/SvJae.
C57BL/6J-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of these mice was predominantly C57BL/6J. There was likely also some contribution from 129S4/SvJae and possibly some from unspecified strain(s).
C57BL/6J-Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Double heterozygous mice. The genetic background of these mice was predominantly C57BL/6J. There was likely also some contribution from 129S4/SvJae and some other unspecified strain.
FVB-Gt(ROSA)26Sortm1(Luc)Kael Krastm4Tyj targeted mutation (conditional) &
transgenic
Heterozygous Kras and transgenic mice on an FVB background with possible contributions from129S6/SvEvTac and 129S4/SvJae.
FVB-Gt(ROSA)26Sortm1(Luc)Kael Krastm4Tyj Stk11tm1.1Rdp targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Stk11, and transgenic mice on an FVB background with possible contributions from 129S6/SvEvTac and 129S4/SvJae.
FVB-Gt(ROSA)26Sortm1(Luc)Kael Krastm4Tyj Trp53tm1Brn targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Trp53, and transgenic mice on an FVB background with possible contributions from 129S6/SvEvTac, 129S4/SvJae, and 129P2/OlaHsd.
FVB-Krastm4Tyj targeted mutation (conditional) Heterozygous mice on an FVB background with possible contribution from 129S4/SvJae.
FVB-Krastm4Tyj Stk11tm1.1Rdp targeted mutation (conditional) Heterozygous Kras, homozygous Stk11 mice on an FVB background with possible contributions from129S6/SvEvTac and 129S4/SvJae.
FVB-Krastm4Tyj Trp53tm1Brn targeted mutation (conditional) Heterozygous Kras, homozygous Trp53 mice on an FVB background with possible contributions from 129S4/SvJae and 129P2/OlaHsd.
STOCK Apctm2Rak Krastm4Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout)
Background contained contributions from "129/Sv", C57BL/6J, and SJL. Mice were homozygous for the Apctm2Rak conditional mutation and heterozygous for the targeted activated allele Krastm4Tyj.
STOCK Cdkn2atm1Rdp Krastm4Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout)
Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were homozygous for Cdkn2atm1Rdp and heterozygous for Krastm4Tyj.
STOCK Cdkn2atm1Rdp/+ Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Background had contributions from FVB/N, C57BL/6J, SJL, and multiple 129 substrains. Mice were heterozygous Krastm4Tyj and Cdkn2atm1Rdp and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.
STOCK Cdkn2atm2.1Rdp Krastm4Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout)
Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were homozygous for Cdkn2atm2.1Rdp and heterozygous for Krastm4Tyj.
STOCK Gt(ROSA)26Sortm1(EYFP)Cos Krastm4Tyj/+ Nkx3-1tm4(cre/ERT2)Mms/+ Ptentm1Hwu targeted mutation (conditional) &
targeted mutation (knock-in)
Compound mutant mice. This STOCK genetic background included C57BL/6, "129/Sv" (including 129S6/SvEvTac, 129S4/SvJae, and 129X1/SvJ), and FVB.
STOCK Gt(ROSA)26Sortm1(EYFP)Cos Krastm4Tyj/+ Tg(Krt1-15-cre/PGR)22Cot targeted mutation (conditional) &
transgenic
Heterozygous mice carrying the transgenes on a mixed C57BL/6J, SJL/J, 129S4/SvJae, 129X1/SvJ background.
STOCK Gt(ROSA)26Sortm1(EYFP)Cos Krastm4Tyj/+ Tg(Krt1-15-cre/PGR)22Cot Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was a mix of C57BL/6J, SJL/J, 129S4/SvJae, 129P2/OlaHsd, 129X1/SvJ, and FVB/N.
STOCK Gt(ROSA)26Sortm2(sb11)Njen Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr TgTn(sb-T2/Onc2)#Njen targeted mutation (conditional) &
transgenic
Compound mutant mice with all alleles heterozygous or hemizygous. This STOCK genetic background included C57BL/6 (including the C57BL/6J substrain), DBA/2, C3H, and 129 (including the 129S4/SvJae substrain).
STOCK Krastm4Tyj Tg(Msx2-cre)5Rem targeted mutation (conditional) &
transgenic
Heterozygous mice on a mixed CD-1, C57BL/6, and 129X1/SvJ genetic background.
STOCK Krastm4Tyj/+ targeted mutation (conditional) Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were heterozygous for the Kras mutant allele.
STOCK Krastm4Tyj/+ Nkx3-1tm4(cre/ERT2)Mms/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Compound mutant mice. This STOCK genetic background included C57BL/6, "129/Sv" (including 129S6/SvEvTac and 129S4/SvJae), and FVB.
STOCK Krastm4Tyj/+ Nkx3-1tm4(cre/ERT2)Mms/+ Ptentm1Hwu targeted mutation (conditional) &
targeted mutation (knock-in)
Compound mutant mice. This STOCK genetic background included C57BL/6, "129/Sv" (including 129S6/SvEvTac and 129S4/SvJae), and FVB.
STOCK Krastm4Tyj/+ Ppp6ctm1Shma Tg(KRT14-cre/ERT)20Efu targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Ppp6c mice carrying the transgene on a mixed C57BL/6, CBA, CD-1 background with contribution from 129S4/SvJae.
STOCK Krastm4Tyj/+ Ptentm1Hwu targeted mutation (conditional) Heterozygous Kras, homozygous Pten mice on a mixed C57BL/6, BALB/c, 129S4/SvJae background with possible additional contributions from 129S1/Sv and SJL.
STOCK Krastm4Tyj/+ Stk11?/+ targeted mutation (conditional) &
targeted mutation (knockout)
Mice had a mixed background of ~75% C57BL/6 & ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were het for Krastm4Tyj and het for either the "tm1.1Rdp" or "tm1.2Rdp" allele of Stk11.
STOCK Krastm4Tyj/+ Stk11tm1.1Rdp targeted mutation (conditional) Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were heterozygous for Krastm4Tyj and homozygous for Stk11tm1.1Rdp.
STOCK Krastm4Tyj/+ Stk11tm1.1Rdp/+ targeted mutation (conditional) Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were heterozygous for the Krastm4Tyj and Stk11tm1.1Rdp targeted mutations.
STOCK Krastm4Tyj/+ Stk11tm1.1Rdp/Stk11? targeted mutation (conditional) &
targeted mutation (knockout)
Background was ~75% C57BL/6 & ~25% FVB/N plus some "129/SvEv" & possibly other 129 substrains and/or SJL. Mice were het for Krastm4Tyj and either homozygous "tm1.1Rdp" or mixed "tm1.1Rdp/1.2Rdp" at Stk11
STOCK Krastm4Tyj/+ Stk11tm1.1Rdp/Stk11tm1.2Rdp targeted mutation (conditional) &
targeted mutation (knockout)
Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were heterozygous for Krastm4Tyj and carried two mutant alleles of Stk11.
STOCK Krastm4Tyj/+ Stk11tm1.2Rdp/+ targeted mutation (conditional) Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were heterozygous for the Krastm4Tyj and Stk11tm1.2Rdp targeted mutations.
STOCK Krastm4Tyj/+ Tg(KRT14-cre/ERT)20Efu targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on a mixed C57BL/6, CBA, CD-1 background with contribution from 129S4/SvJae.
STOCK Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der Trp53tm1Brn targeted mutation (conditional) &
transgenic
Homozygous Trp53tm1Brn, heterozygous Krastm4Tyj mice also carrying the Tg(KRT5-cre/PGR)1Der transgene on a mixed FVB, "129/Sv", and C57BL/6 genetic background.
STOCK Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Heterozygous Trp53tm1Brn, Krastm4Tyj mice also carrying the Tg(KRT5-cre/PGR)1Der transgene on a mixed FVB, "129/Sv", and C57BL/6 genetic background.
STOCK Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der Trp53tm1Brn/Trp53tm1Glo targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Heterozygous Trp53tm1Brn/Trp53tm1Glo, Krastm4Tyj mice also carrying the Tg(KRT5-cre/PGR)1Der transgene on a mixed FVB, "129/Sv", and C57BL/6 genetic background.
STOCK Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der Trp53tm1Glo/+ targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Heterozygous Trp53tm1Glo, Krastm4Tyj mice also carrying the Tg(KRT5-cre/PGR)1Der transgene on a mixed FVB, "129/Sv", and C57BL/6 genetic background.
STOCK Krastm4Tyj/+ Tg(Krt1-15-cre/PGR)22Cot targeted mutation (conditional) &
transgenic
Heterozygous mice carrying the transgene on a mixed C57BL/6J, SJL/J, 129S4/SvJae background.
STOCK Krastm4Tyj/+ Tg(Krt1-15-cre/PGR)22Cot Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was a mix of C57BL/6J, SJL/J, 129S4/SvJae, 129P2/OlaHsd, and FVB/N.
STOCK Krastm4Tyj/+ Tg(Vil1-cre/ERT2)23Syr targeted mutation (conditional) &
transgenic
Compound mutant mice with all alleles heterozygous or hemizygous. This STOCK genetic background included C57BL/6 (including the C57BL/6J substrain), DBA/2, C3H, and 129 (including the 129S4/SvJae substrain).
STOCK Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Mice had a mixed background of ~75% C57BL/6 and ~25% FVB/N plus some "129/SvEv" and possibly some other 129 substrains and/or SJL. Mice were homozygous for Trp53tm1Brn and heterozygous for Krastm4Tyj.
[not specified]-Atg7tm1Tchi Krastm4Tyj/+ targeted mutation (conditional) Heterozygous Kras, homozygous Atg7 mice on an unspecified background with possible contributions from 129S4/SvJae, C57BL/6NCrlj, and CBA/JNcrlj.
[not specified]-Atg7tm1Tchi Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Heterozygous Kras, homozygous Trp53, Atg7 mice on an unspecified background with possible contributions from 129P2/OlaHsd, 129S4/SvJae, C57BL/6NCrlj, and CBA/JNcrlj.
[not specified]-Atg7tm1Tchi/+ Krastm4Tyj/+ targeted mutation (conditional) Heterozygous Kras, Atg7 mice on an unspecified background with possible contributions from 129P2/OlaHsd, 129S4/SvJae, C57BL/6NCrlj, and CBA/JNcrlj.
[not specified]-Cdh1tm2Kem Gt(ROSA)26Sortm1Sor Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu Tgfbr2tm1.2Hlm targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt19, Kras, homozygous Cdh1 mutant mice carrying the transgene on an unspecified background with contribution from 129S6/SvEvTac, 129X1/SvJ, 129S4/SvJ, 129S4/SvJaeSor, and 129S1/Sv.
[not specified]-Cdh1tm2Kem Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu targeted mutation (conditional) &
targeted mutation (knock-in)
Homozygous Cdh1, heterozygous Kras, Krt19 mutant mice on an unspecified background with contribution from 129S6/SvEvTac, 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
[not specified]-Cdh1tm2Kem Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu Tgfbr2tm1.2Hlm targeted mutation (conditional) &
targeted mutation (knock-in)
Homozygous Tgfbr2, Cdh1, heterozygous Kras, Krt19 mice on an unspecified background with contribution from 129S6/SvEvTac, 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
[not specified]-Cdh1tm2Kem Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn Tgfbr2tm1.2Hlm targeted mutation (conditional) &
transgenic
Homozygous Tgfbr2, heterozygous Kras mutant mice also carrying the transgene on an unspecified background with contribution from 129S6/SvEvTac, C57BL/6, DBA/2, 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
[not specified]-Cdkn2atm2.1Nesh Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, and possibly some other strain(s).
[not specified]-Cdkn2atm2.1Nesh Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, 129P2/OlaHsd, and possibly some other strain(s).
[not specified]-Cdkn2atm2.1Nesh Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, 129P2/OlaHsd, and possibly some other strain(s).
[not specified]-Cdkn2atm2.1Nesh/+ Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, 129P2/OlaHsd, and possibly some other strain(s).
[not specified]-Cdkn2atm2.1Nesh/+ Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, 129P2/OlaHsd, and possibly some other strain(s).
[not specified]-Cdkn2atm4Rdp Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but included C57BL/6, CBA, and likely some FVB/N.
[not specified]-Cdkn2atm4Rdp/+ Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but included C57BL/6, CBA, and likely some FVB/N.
[not specified]-Ctnnb1tm1Mmt Krastm4Tyj/+ Tg(Upk2-cre)6Xrw targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj, homozygous Ctnnb1tm1Mmt mice also carrying the Tg(Upk2-cre)6Xrw transgene on an unspecified background with some FVB/N, 129S4/SvJae, and/or 129X1/SvJae contribution from the parental ES cells.
[not specified]-Ctnnb1tm1Mmt/+ Krastm4Tyj/+ Tg(Cited1-cre/ERT2,-EGFP)1Mdca targeted mutation (conditional) &
transgenic
Heterozygous Ctnnb1tm1Mmt, Krastm4Tyj, transgenic Tg(Cited1-cre/ERT2,-EGFP)1Mdca mice on an unspecified genetic background which may have contained contributions from 129X1/SvJ, 129S4/SvJae, and FVB.
[not specified]-Ctnnb1tm1Mmt/+ Krastm4Tyj/+ Tg(Ggt1-cre)M3Egn targeted mutation (conditional) &
transgenic
Heterozygous Ctnnb1tm1Mmt, Krastm4Tyj, transgenic Tg(Ggt1-cre)M3Egn mice on an unspecified background. Genetic background may have contained contributions from 129X1/SvJ, 129S4/SvJae, and FVB.
[not specified]-Dlc1Gt(XE082)Byg/+ Krastm4Tyj/+ gene trapped &
targeted mutation (conditional)
Double heterozygous mice. The genetic background of these mice was not specified but included at least 129P2/OlaHsd and 129S4/SvJae and likely a high percentage of C57BL/6.
[not specified]-Dnmt3atm1Jae Krastm4Tyj/+ targeted mutation (conditional) Homozygous Dnmt3a, heterozygous Kras mice on an unspecified background that contained contributions from at least C57BL/6 and 129S4/SvJae.
[not specified]-Dnmt3atm1Jae/+ Krastm4Tyj/+ targeted mutation (conditional) Homozygous Dnmt3a, heterozygous Kras mice on an unspecified background that contained contributions from at least C57BL/6 and 129S4/SvJae.
[not specified]-Fgfr3tm4Cxd/+ Krastm4Tyj/+ Tg(Upk2-cre)6Xrw targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Heterozygous Fgfr3, Kras, and transgenic mice on an unspecified background with possible contributions from 129S6/SvEvTac, 129S4/SvJae, and FVB/N.
[not specified]-Gclmtm1Tjka Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) &
targeted mutation (knockout)
Heterozygous Krastm4Tyj, homozygous Trp53tm1Brn, Gclmtm1Tjka mice on an unspecified genetic background with possible contribution from 129X1/SvJ, 129S1/Sv, C57BL/6, 129P2/OlaHsd, and/or 129S4/SvJae.
[not specified]-Gpr55tm1Tigm Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, homozygous Grp55 mice carrying the transgene on an unspecified background with contribution from 129S4/SvJae, 129S5/SvEvBrd and FVB/N.
[not specified]-Gpr55tm1Tigm Krastm4Tyj/+ Trp53tm2Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, Trp53, homozygous Grp55 mice carrying the transgene on an unspecified background with contribution from 129S4/SvJae, 129S5/SvEvBrd and FVB/N.
[not specified]-Gt(ROSA)26Sortm1(CAG-EGFP)Blh/Gt(ROSA)26Sor Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Scgb1a1tm1(cre/ERT)Blh, Krastm4Tyj mice also carrying Gt(ROSA)26Sortm1(CAG-EGFP)Blh on an unspecified background with possible contributions from 129S4/SvJae and/or 129S6/SvEvTac.
[not specified]-Gt(ROSA)26Sortm1(EYFP)Cos Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, homozygous Trp53 mice carrying the transgene on an unspecified background with contributions from 129P2/OlaHsd, 129S4/SvJae, and 129X1/SvJ from the parental ES cells.
[not specified]-Gt(ROSA)26Sortm1(MAML1)Wsp/Gt(ROSA)26Sor Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Scgb1a1tm1(cre/ERT)Blh, Krastm4Tyj mice also carrying Gt(ROSA)26Sortm1(MAML1)Wsp on an unspecified background with possible contributions from 129S4/SvJae and/or 129S6/SvEvTac.
[not specified]-Gt(ROSA)26Sortm1(Notch1)Dam Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Scgb1a1, Kras mutant mice also carrying the Gt(ROSA)26Sortm1(Notch1)Dam allele on an unspecified background with possible contributions from 129S4/SvJae, 129S4/SvJaeSor, and/or 129S6/SvEvTac.
[not specified]-Gt(ROSA)26Sortm1(Pik3ca*H1047R)Egan/+ Krastm4Tyj/+ Tg(MMTV-cre)#Tfln targeted mutation (conditional) &
transgenic
Complex mutant mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae and some 129S6/SvEvTac.
[not specified]-Gt(ROSA)26Sortm1(pb)Brd Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least 129S7/SvEvBrd-Hprt+, 129S4/SvJae, and C57BL/6 and/or CBA.
[not specified]-Gt(ROSA)26Sortm1(pb)Brd Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam TgTn(pb-sb-ATP1)#Brd targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least 129S7/SvEvBrd-Hprt+, 129S4/SvJae, and possibly FVB or C57BL/6 and/or CBA.
[not specified]-Gt(ROSA)26Sortm1(pb)Brd Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam TgTn(pb-sb-ATP1)H39Brd targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least 129S7/SvEvBrd-Hprt+, 129S4/SvJae, C57BL/6 and possibly CBA.
[not specified]-Gt(ROSA)26Sortm1(pb)Brd Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam TgTn(pb-sb-ATP1)H44Brd targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least 129S7/SvEvBrd-Hprt+, 129S4/SvJae, C57BL/6 and possibly CBA.
[not specified]-Gt(ROSA)26Sortm1(pb)Brd Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam TgTn(pb-sb-ATP1)S2Brd targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least 129S7/SvEvBrd-Hprt+, 129S4/SvJae, FVB, and C57BL/6 and/or CBA.
[not specified]-Gt(ROSA)26Sortm1Sor Krastm4Tyj/+ Krt19tm1(cre/ERT)GguTgfbr2tm1.2Hlm targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt19, Kras, homozygous Tgfbr2 mutant mice also carrying the transgene on an unspecified background with contribution from 129S6/SvEvTac, 129S4/SvJ, and 129S4/SvJaeSor.
[not specified]-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze Hes1tm1Kag Krastm4Tyj/+ Tg(Cela1-cre/ERT2)1Stof targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Hes1 mice carrying the transgenes on an unspecified background with contribution from C57BL/6NCrlj, CBA, 129S4/SvJae and SJL.
[not specified]-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze Krastm4Tyj/+ Tg(Cela1-cre/ERT2)1Stof targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgenes on an unspecified background with contribution from C57BL/6NCrlj, CBA, 129S4/SvJae and SJL.
[not specified]-Hes1tm1Kag Krastm4Tyj/+ Tg(Cela1-cre/ERT2)1Stof targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Hes1 mice carrying the transgene on an unspecified background with contribution from C57BL/6NCrlj, CBA, 129S4/SvJae and SJL.
[not specified]-Hes1tm1Kag Krastm4Tyj/+ Tg(Cela1-cre/ERT2)1Stof Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Homozygous Hes1, eterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6NCrlj, CBA, 129S4/SvJae and SJL.
[not specified]-Hrastm1Esn Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Hras, heterozygous Kras mice carrying the transgene on an unspecified background with possible contribution from 129X1/SvJ, 129S4/SvJae, FVB, and FVB/N.
[not specified]-Hrastm1Esn Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Hras, Trp53, heterozygous Kras mice carrying the transgene on an unspecified background with possible contribution from 129X1/SvJ, 129S4/SvJae, FVB, and FVB/N.
[not specified]-Hrastm1Esn Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Hras, Trp53, heterozygous Kras mice carrying the transgene on an unspecified background with possible contribution from 129X1/SvJ, 129S4/SvJae, FVB, and FVB/N.
[not specified]-Igs2tm1(ACTB-EGFP,-tdTomato)Luo/Igs2tm2(ACTB-tdTomato,-EGFP)Luo Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
targeted mutation (other) &
transgenic
Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae, 129S2/SvPas, FVB/N, and also 129X1/SvJ and/or 129S1/Sv. There may have been other strain contributions.
[not specified]-Igs2tm1(ACTB-EGFP,-tdTomato)Luo/Igs2tm2(ACTB-tdTomato,-EGFP)Luo Krastm4Tyj/+ Trp53tm1Tyj/+ targeted mutation (conditional) &
targeted mutation (knockout) &
targeted mutation (other)
Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae, 129S2/SvPas, and also 129X1/SvJ and/or 129S1/Sv. There may have been other strain contributions.
[not specified]-Klf5tm1Jaw Krastm4Tyj/+ targeted mutation (conditional) Background unspecified. Mice were homozygous for Klf5tm1Jaw and heterozygous for Krastm4Tyj.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Mice carrying a Cre-activatable allele of Kras2 encoding an oncogenic protein (G12D mutation). The genetic background of the animals was not specified.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Mice were on a mixed genetic background and heterozygous for the Krastm4Tyj mutation. Mice were either 129S4/SvJae or 129S4/SvJae x C3H/HeJ (F1 mixed background).
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of these mice was not specified.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of these mice was not specified.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Background unspecified. Mice were heterozygous for Krastm4Tyj mutation.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of the animals was not specified but included at least some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Homozygous Dnmt3a, heterozygous Kras mice on an unspecified background that contained contributions from at least C57BL/6 and 129S4/SvJae.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice on an unspecified background with contribution from 129S4/SvJae and possibly C57BL/6 and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of these mice was not specified but included at least 129P2/OlaHsd and 129S4/SvJae and likely a high percentage of C57BL/6.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice on an unspecified background with possible contributions from 129S4/SvJae, C57BL/6NCrlj and CBA/JNcrlj.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) Heterozygous mice. The genetic background of these mice was not specified but contained some 129S4/SvJae, likely some C57BL/6, and possibly some 129P2/OlaHsd, FVB, and/or other strain(s).
[not specified]-Krastm4Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras mutant mice on an unspecified background with contribution from 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Gt(ROSA)26Sortm2(STAT3,EGFP)Cgn/+ Tg(MMTV-cre)#Tfln targeted mutation (conditional) &
transgenic
Complex mutant mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae and some B6.Cg-Thy1a.
[not specified]-Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Krt19 mutant mice on an unspecified background with contribution from 129S6/SvEvTac and 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Krt19tm1(cre/ERT)Ggu Tgfbr2tm1.2Hlm targeted mutation (conditional) &
targeted mutation (knock-in)
Homozygous Tgfbr2, heterozygous Kras, Krt19 mutant mice on an unspecified background with contribution from 129S6/SvEvTac and 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Lcn2tm1Aade Tg(Cela1-cre/ERT)1Lgdn targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Lcn2, heterozygous Kras mice also carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Nos2tm1Lau targeted mutation (conditional) &
targeted mutation (knockout)
Heterozygous Kras, homozygous Nos2 mice on an unspecified background with contribution from 129S4/SvJae, C57BL/6, and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Ptentm1Hwu targeted mutation (conditional) Mice were on a mixed genetic background, homozygous for Ptentm1Hwu and heterozygous for Krastm4Tyj. BALB/c Pten mice rederived on C57BL/6 were crossed to 129S4/SvJae Kras mice.
[not specified]-Krastm4Tyj/+ Ptentm1Hwu targeted mutation (conditional) Homozygous Pten, heterozygous Kras mice on an unspecified background with contributions from at least 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Ptentm1Hwu/+ Tg(Upk2-cre)6Xrw targeted mutation (conditional) &
transgenic
Heterozygous Kras, Pten, and transgenic mice on an unspecified background with possible contributions from 129X1/SvJ, 129S4/SvJ, and FVB/N.
[not specified]-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw targeted mutation (conditional) &
transgenic
Heterozygous Kras mutant mice also carrying the transgene on an unspecified background with contribution from 129X1/SvJ, 129S4/SvJae, and 129S1/Sv.
[not specified]-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Mice carry a Cre-activatable allele of Kras2 encoding an oncogenic protein (G12D mutation) and the transgene Ptf1atm1.1(cre)Cvw.
[not specified]-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Ptf1a mice on an unspecified background with contribution from C57BL/6, 129S4/SvJae, 129S2/SvPas, and FVB/N.
[not specified]-Krastm4Tyj/+ Ptf1atm1.1(cre)Cvw/+ Trp53tm1Brn targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Ptf1a, homozygous Trp53 mice on an unspecified background with contribution from C57BL/6, 129S4/SvJae, 129S2/SvPas, and FVB/N.
[not specified]-Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ Sox2tm1Lpev targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Scgb1a1tm1(cre/ERT)Blh, Krastm4Tyj, homozygous Sox2tm1Lpev mice on an unspecified background with possible contributions from 129S4/SvJae, 129S/SvEv, and/or 129S6/SvEvTac.
[not specified]-Krastm4Tyj/+ Scgb1a1tm1(cre/ERT)Blh/+ Sox2tm1Lpev/+ targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Scgb1a1tm1(cre/ERT)Blh, Krastm4Tyj, Sox2tm1Lpev mice on an unspecified background with possible contributions from 129S4/SvJae, 129S/SvEv, and/or 129S6/SvEvTac.
[not specified]-Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn/? targeted mutation (conditional) &
transgenic
Heterozygous Kras and transgenic mice on an unspecified background with contributions from at least 129S4/SvJae, C57BL/6, 129P2/OlaHsd, and DBA.
[not specified]-Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn/? Trp53tm1Brn targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Trp53, and transgenic mice on an unspecified background with contributions from at least 129S4/SvJae, C57BL/6, 129P2/OlaHsd, and DBA.
[not specified]-Krastm4Tyj/+ Speer6-ps1Tg(Alb-cre)21Mgn/? Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53, and transgenic mice on an unspecified background with contributions from at least 129S4/SvJae, C57BL/6, 129P2OlaHsd, and DBA.
[not specified]-Krastm4Tyj/+ Stk11tm1.1Rdp targeted mutation (knockout) Mice were on a mixed background but contained contribution from at least 129S4/SvJae. Mice were heterozygous for Krastm4Tyj and homozygous for Stk11tm1.1Rdp.
[not specified]-Krastm4Tyj/+ Stk11tm1.1Rdp Tg(Tyr-cre/ERT2)13Bos targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, and 129S6/SvEvTac.
[not specified]-Krastm4Tyj/+ Stk11tm1.1Rdp Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, 129S6/SvEvTac, and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Stk11tm1.1Sjm targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, homozygous Stk11 mutant mice on an unspecified background with contribution from 129S4/SvJae and C57BL/6.
[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm1Brn/+ targeted mutation (conditional) &
transgenic
Background was not specified but contained at least some FVB/N and multiple 129 substrains. Mice were heterozygous for Krastm4Tyj and Trp53tm1Brn and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.
[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Glo/+ targeted mutation (conditional) &
transgenic
Background was not specified but contained at least some FVB/N and multiple 129 substrains. Mice were heterozygous for Krastm4Tyj and Trp53tm2Glo and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.
[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj targeted mutation (conditional) &
transgenic
Background was not specified but contained at least some FVB/N and multiple 129 substrains. Mice were heterozygous Krastm4Tyj, homozygous Trp53tm2Tyj, & carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.
[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Background was not specified with contributions from FVB/N and multiple 129 substrains. Mice were heterozygous for Krastm4Tyj and Trp53tm2Tyj and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.
[not specified]-Krastm4Tyj/+ Tg(CDX2-cre/ERT2)752Erf targeted mutation (conditional) &
transgenic
Heterozygous Kras mutant mice also carrying the Tg(CDX2-cre/ERT2)752Erf transgene on an unspecified background with possible contributions from 129S4/SvJae, C57BL/6J, C57BL/6, and/or SjL/J.
[not specified]-Krastm4Tyj/+ Tg(CMV-rtTA)4Bjd Tg(TetO-MYC*)4Gev targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice also carrying the Tg(CMV-rtTA)4Bjd and Tg(TetO-MYC*)4Gev transgenes on an unspecified background with possible contribution from 129S4/SvJae, NMRI, CBA, and/or C57BL/6.
[not specified]-Krastm4Tyj/+ Tg(CMV-rtTA)4Bjd Tg(TetO-MYC*)4Gev Trp53tm1Gev targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Trp53 mutant mice also carrying the Tg(CMV-rtTA)4Bjd and Tg(TetO-MYC*)4Gev transgenes on an unspecified background with possible contribution from 129P2/OlaHsd, 129S4/SvJae, NMRI, CBA, and/or C57BL/6.
[not specified]-Krastm4Tyj/+ Tg(Cela1-cre/ERT)1Lgdn targeted mutation (conditional) &
transgenic
Heterozygous Kras mice also carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Tg(Cela1-cre/ERT2)1Stof targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on an unspecified background with contribution from C57BL/6NCrlj, CBA, 129S4/SvJae and SJL.
[not specified]-Krastm4Tyj/+ Tg(Cela1-cre/ERT2)1Stof Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6NCrlj, CBA, 129S4/SvJae and SJL.
[not specified]-Krastm4Tyj/+ Tg(Cited1-cre/ERT2,-EGFP)1Mdca targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj, transgenic Tg(Cited1-cre/ERT2,-EGFP)1Mdca mice on an unspecified genetic background which may have contained contributions from 129X1/SvJ, 129S4/SvJae, and FVB.
[not specified]-Krastm4Tyj/+ Tg(Ggt1-cre)M3Egn targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj, transgenic Tg(Cited1-cre/ERT2,-EGFP)1Mdca mice on an unspecified genetic background which may have contained contributions from 129X1/SvJ, 129S4/SvJae, C57BL/6, and SJL.
[not specified]-Krastm4Tyj/+ Tg(KRT14-cre/PGR)1Der targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice containing the Tg(KRT14-cre/PGR)1Der transgene on an unspecified background containing possible contributions from 129S4/SvJae, ICR, and/or FVB.
[not specified]-Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice containing the Tg(KRT5-cre/PGR)1Der transgene on an unspecified background containing possible contributions from 129S4/SvJae, ICR, and/or FVB.
[not specified]-Krastm4Tyj/+ Tg(KRT5-cre/PGR)1Der Trp53tm1Glo/+ targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Mice heterozygous for the Krastm4Tyj and Trp53tm1Glo mutations and also carrying the Tg(KRT5-cre/PGR)1Der transgene on an unspecified background with possible contribution from 129S4/SvJae, ICR, and/or FVB.
[not specified]-Krastm4Tyj/+ Tg(MMTV-cre)#Tfln targeted mutation (conditional) &
transgenic
Complex mutant mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Mice carry a Cre-activatable allele of Kras2 encoding an oncogenic protein (G12D mutation) and the transgene Tg(Pdx1-cre)6Tuv.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Background was not specified but contained contributions from at least FVB/N and multiple 129 substrains. Mice were heterozygous for Krastm4Tyj and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on an unspecified background with possible contribution from 129X1/SvJ, 129S4/SvJae, FVB, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae and FVB/N. There may have been other strain contributions.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras mice carrying the transgene on an unspecified background with contribution from 129S4/SvJae and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Tyj targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, 129S2/SvPas, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, 129S2/SvPas, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with possible contribution from 129X1/SvJ, 129S4/SvJae, FVB, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Homozygous Trp53, heterozygous Kras mice carrying the transgene on an unspecified background with possible contribution from 129X1/SvJ, 129S4/SvJae, FVB, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae and FVB/N. There may have been other strain contributions.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm4Att/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm5Tyj/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but included C57BL/6 and CBA.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam targeted mutation (conditional) &
transgenic
Heterozygous Kras mice also transgenic for the Tg(Pdx1-cre)89.1Dam transgene on an unspecified background with possible contributions from 129S4/SvJae, C57BL/6, and/or CBA.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least 129S4/SvJae, and C57BL/6 and/or CBA.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)89.1Dam Trp53inp1tm1Acar targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, homozygous Trp53inp1 mutant mice also transgenic for the Tg(Pdx1-cre)89.1Dam transgene on an unspecified background with possible contributions from 129S4/SvJae, 129/Sv, C57BL/6, and/or CBA.
[not specified]-Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB and 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn targeted mutation (conditional) &
transgenic
Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129S4/SvJae, and 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Tg(Upk2-cre)6Xrw targeted mutation (conditional) &
transgenic
Heterozygous Kras and transgenic mice on an unspecified background with possible contributions from 129S4/SvJ and FVB/N.
[not specified]-Krastm4Tyj/+ Tg(Upk2-cre)6Xrw targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice also carrying the Tg(Upk2-cre)6Xrw transgene on an unspecified background with some FVB/N and 129S4/SvJae contribution from the parental ES cells.
[not specified]-Krastm4Tyj/+ Tg(Upk2-cre)6Xrw targeted mutation (conditional) &
transgenic
Heterozygous Krastm4Tyj mice also carrying the Tg(Upk2-cre)6Xrw transgene on an unspecified background with some FVB/N and 129S4/SvJae contribution from the parental ES cells.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Mice were heterozygous for the Kras allele and homozygous for the Trp53 allele. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Heterozygous Kras, homozygous Trp53 mice on an unspecified background with possible contributions from 129P2/OlaHsd, 129S4/SvJae, C57BL/6NCrlj, and CBA/JNcrlj.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) &
targeted mutation (knockout)
Heterozygous Krastm4Tyj, homozygous Trp53tm1Brn mice on an unspecified background with possible contribution from 129X1/SvJ, 129S1/Sv, C57BL/6, 129P2/OlaHsd, and/or 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Compound mutant mice. The genetic background of these mice was not specified but contained some 129S4/SvJae, some 129P2/OlaHsd, likely some C57BL/6 and FVB, and possibly some other strain(s).
[not specified]-Krastm4Tyj/+ Trp53tm1Brn targeted mutation (conditional) Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae and 129P2/OlaHsd. There may have been other strain contributions.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn/+ targeted mutation (conditional) Double heterozygous mice. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn/Trp53tm2Tyj targeted mutation (conditional) Mice were heterozygous for the Kras allele and carried multiple Trp53 alleles. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd and some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn/Trp53tm2Tyj targeted mutation (conditional) Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae, 129P2/OlaHsd, and 129S2/SvPas. There may have been other strain contributions.
[not specified]-Krastm4Tyj/+ Trp53tm1Brn/Trp53tm3Tyj targeted mutation (conditional) Mice were heterozygous for the Kras allele and carried multiple Trp53 alleles. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd and some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Trp53tm2Tyj/+ targeted mutation (conditional) Double heterozygous mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Trp53tm2Tyj/+ Tg(Pdx1-cre)6Tuv targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from 129S4/SvJae and FVB/N.
[not specified]-Krastm4Tyj/+ Trp53tm3Tyj/+ targeted mutation (conditional) Double heterozygous mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae.
[not specified]-Krastm4Tyj/+ Tsc1tm1Djk targeted mutation (conditional) Mice were on a mixed background but contained contribution from at least 129S4/SvJae. Mice were heterozygous for Krastm4Tyj and homozygous for Tsc1tm1Djk.
[not specified]-Krastm4Tyj/+ Tsc1tm1Djk/+ targeted mutation (knockout) Mice were on a mixed background but contained contribution from at least 129S4/SvJae. Mice were heterozygous for Krastm4Tyj and Tsc1tm1Djk.
[not specified]-Krastm4Tyj/+Tg(Pdx1-cre)6Tuv Trp53tm3Att/+ targeted mutation (conditional) &
transgenic
Heterozygous Kras, Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, and FVB/N.
[not specified]-Ptf1atm1.1(cre)Cvw/+ Krastm4Tyj/+ Tg(Erbb2*)#Maed targeted mutation (conditional) &
transgenic
Heterozygous Ptf1a, Kras mutant mice also carrying the transgene on an unspecified background with contribution from 129X1/SvJ, 129S4/SvJae, and 129S1/Sv.