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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Strain Search Results  
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121 matching items displayed.
Strain Name Strain Type Strain Notes
129/Sv-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. "p53+/-". The genetic background of these mice was 129S7/SvEvBrd-Hprt+ and 129/Sv of an unspecified substrain or combination of substrains.
129;B6-Brca1tm2Mak Tg(Wap-cre)11738Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Trp53tm1Brd, homozygous Brca1tm2Mak mice also carrying the Tg(Wap-cre)11738Mam transgene on a mixed 129/J and C57BL/6 background with possible contributions from 129P2/OlaHsd, 129S7/SvEvBrd, and SJL.
129S-Fancd2tm1Hou Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was 129S with contributions from at least 129S4/SvJae and 129S7/SvEvBrd-Hprt1+.
129S-Fancd2tm1Hou/+ Trp53tm1Brd/+ targeted mutation (knockout) Double heterozygous mice. The genetic background of these mice was 129S with contributions from at least 129S4/SvJae and 129S7/SvEvBrd-Hprt1+.
129S-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was 129S with contributions from at least 129S7/SvEvBrd-Hprt1+ and likely some 129S4/SvJae.
129S4-Fancd2?/+ Trp53tm1Brd/+ targeted mutation (knockout) Transgenic mice that were either wild-type at Fancd2 or heterozygous for Fancd2tm1Hou. These were control mice on 129S4/SvJae background with some contribution from 129S7/SvEvBrd-Hprt+.
129S4-Fancd2tm1Hou Trp53tm1Brd/+ targeted mutation (knockout) Mice were homoozygous for the Fancd2tm1Hou and heterozygous for the Trp53tm1Brd mutations on a 129S4/SvJae background with some contribution from 129S7/SvEvBrd-Hprt+
129S4-Fancd2tm1Hou/+ Trp53tm1Brd/+ targeted mutation (knockout) Mice were heterozygous for the Fancd2tm1Hou and Trp53tm1Brd mutations on a 129S4/SvJae background with some contribution from 129S7/SvEvBrd-Hprt+.
129S4-Trp53tm1Brd/+ targeted mutation (knockout) Mice were heterozygous for the Trp53tm1Brd mutation on a 129S4/SvJae background with some contribution from 129S7/SvEvBrd-Hprt+.
B6.129S7-Trp53tm1Brd/+ congenic &
targeted mutation (knockout)
Heterozygous mice. These mice had been backcrossed to C57BL/6. The targeted mutation was generated in 129S7/SvEvBrd-Hprt+-derived ES cells.
B6.129S7-Trp53tm1Brd/+ congenic &
targeted mutation (knockout)
Heterozygous mice. The genetic background of these mice is congenic for C57BL/6NTac with some contribution from 129S7/SvEvBrd-Hprt+. Mice were purchased from Taconic.
B6129F2-Glipr1tm1Tt Trp53tm1Brd/+ hybrid &
targeted mutation (knockout)
Heterozygous Trp53, homozygous Glipr1 mice on a hybrid C57BL/6, 129/Sv background. 129 substrain was not specified but included at least 129S7/SvEvBrd-Hprt+.
B6129F2-Glipr1tm1Tt/+ Trp53tm1Brd/+ hybrid &
targeted mutation (knockout)
Heterozygous mice on a hybrid C57BL/6, 129/Sv background. 129 substrain was not specified but included at least 129S7/SvEvBrd-Hprt+.
B6129F2-Trp53tm1Brd/+ hybrid &
targeted mutation (knockout)
Heterozygous mice on a hybrid C57BL/6, 129/Sv background. 129 substrain was not specified but included at least 129S7/SvEvBrd-Hprt+.
B6;129-Cdkn2atm1Cjs Trp53tm1Brd/+ targeted mutation (knockout) Cdkn2a homozygote, Trp53 heterozygote. Mice are on mixed C57BL/6 and 129 background (substrains include 129S7/SvEvBrd-Hprt+ and 129X1/SvJ).
B6;129-Cdkn2atm1Cjs/+ Trp53tm1Brd/+ targeted mutation (knockout) Heterozygote for Cdkn2a and Trp53. Mice are on mixed C57BL/6 and 129 background (substrains include 129S7/SvEvBrd-Hprt+ and 129X1/SvJ).
B6;129-Dclre1ctm1Fwa Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (including at least 129S6/SvEvTac and 129S7/SvEvBrd-Hprt1+).
B6;129-Lig4tm1Fwa Trp53tm1Brd/+ targeted mutation (knockout) Mice homozygous for a targeted mutation of Lig4 and heterozygous for a targeted mutation of Trp53. The genetic background was a mix of C57BL/6 and two substrains of 129 (129S7/SvEvBrd-Hprt+ and 129S6/SvEvTac).
B6;129-Rnf8Gt(AS0574)Wtsi Trp53tm1Brd/+ gene trapped &
targeted mutation (knockout)
Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 and "129/J".
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygote for Trp53, wild-type Cdkn2a. Mice are on mixed C57BL/6 and 129 background (substrains include 129S7/SvEvBrd-Hprt+ and 129X1/SvJ).
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was stated to be 75% "129/Sv" (including 129S7/SvEvBrd-Hprt+) and 25% C57BL/6.
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (including at least 129S7/SvEvBrd-Hprt1+ and likely some 129S6/SvEvTac).
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (substrain not specified but it included at least some 129S7/SvEvBrd-Hprt1+).
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (substrain not specified but included at least some 129S7/SvEvBrd-Hprt1+).
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice on a mixed C57BL/6, 129 background. The 129 contribution was from 129S7/SvEvBrd-Hprt+ & may have contained some other 129/Sv. The B6 contribution was from at least C57BL/6NTac but may have had other B6 contributions.
B6;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/J".
B6;129-Trp53tm1Brd/+ Xpctm1Ecf targeted mutation (knockout) These mice were heterozygous for the Trp53 allele and homozygous for the Xpc allele. The genetic background of these mice was stated to be 75% "129/Sv" (including 129S7/SvEvBrd-Hprt+) and 25% C57BL/6.
B6;129-Trp53tm1Brd/+ Xpctm1Ecf/+ targeted mutation (knockout) These mice were heterozygous for both mutant alleles. The genetic background of these mice was stated to be 75% "129/Sv" (including 129S7/SvEvBrd-Hprt+) and 25% C57BL/6.
B6;129/Sv-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous Trp53 mice on a mixed C57BL/6, 129/Sv background with possible contributions from 129S7/SvEvBrd-Hprt+.
B6;129S-Atmtm1Awb Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 and "129/SvEv" (including at least 129S6/SvEvTac and 129S7/SvEvBrd-Hprt1+).
B6;129S-Del(11Gast-Hsd17b1)5Brd +/+ Trp53tm1Brd targeted mutation (knockout) &
targeted mutation (other)
Double heterozygotes with the mutant alleles on opposite copies of chr 11 (in "trans"). The genetic background was a mixture of C57BL/6-Tyrc-Brd and 129S5 and also included some 129S7/SvEvBrd.
B6;129S-Del(11Gast-Hsd17b1)5Brd Trp53tm1Brd/+ + targeted mutation (knockout) &
targeted mutation (other)
Double heterozygotes with the mutant alleles on the same copy of chr 11 (in "cis"). The genetic background was reported to be a mixture of C57BL/6-Tyrc-Brd and 129S5 and also included some 129S7/SvEvBrd.
B6;129S-Rassf1tm1Gpp Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 and 129S (129S1/SvImJ and 129S7/SvEvBrd-Hprt+).
B6;129S-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and 129S (129S1/SvImJ and 129S7/SvEvBrd-Hprt+).
B6;129S7-Rb1tm1Brd/+ Trp53tm1Brd/+ targeted mutation (knockout) Mice were heterozygous for both the Rb1tm1Brd and the Trp53tm1Brd alleles. The genetic background of these mice was a mixture of C57BL/6 and 129S7/SvEvBrd-Hprt+.
B6;129S7-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. "p53+/-". The genetic background of this strain is a mixture of C57BL/6 and 129S7/SvEvBrd-Hprt+.
B6;129S7-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. "p53+/-". The genetic background of this strain is a mixture of C57BL/6 and 129S7/SvEvBrd-Hprt+.
B6;C3-Tg(BLG-CCNE1)2458Mpr Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Mice were heterozygous for the KO and homozygous for the Tg. The genetic background of these mice was ~75% C57BL/6 (containing both C57BL/6J and C57BL/6NTac) and ~25% C3H with some possible residual contribution from 129S7/SvEvBrd.
B6;C3-Tg(BLG-CCNE1*T380A)#Mpr Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Mice were heterozygous for the KO and homozygous for the Tg. The genetic background of these mice was ~75% C57BL/6 (containing both C57BL/6J and C57BL/6NTac) and ~25% C3H with some possible residual contribution from 129S7/SvEvBrd.
B6;C3-Tg(BLG-CCNE1*T380A)#Mpr Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Mice were heterozygous for the KO and hemizygous for the Tg. The genetic background of these mice was ~75% C57BL/6 (containing both C57BL/6J and C57BL/6NTac) and ~25% C3H with some possible residual contribution from 129S7/SvEvBrd.
B6;C3-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was ~75% C57BL/6 (containing both C57BL/6J and C57BL/6NTac) and ~25% C3H with some possible residual contribution from 129S7/SvEvBrd.
B6AF1-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. B6.129S7-Trp53tm1Brd/+ mice (generated using ES cells from 129S7/SvEvBrd-Hprt+ mice and backcrossed to C57BL/6J mice) were crossed one time to A/J mice.
C57BL/6-Brca1tm2Cxd Trp53tm1Brd/+ Tg(MMTV-cre)4Mam targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compount mutant mice. The genetic background of these mice was predominantly C57BL/6. It also contained some 129S6/SvEvTac, some 129S7/SvEvBrd-Hprt+, some FVB, and possibly some other strain(s).
C57BL/6-Cd1tm1Gru Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. The genetic background was C57BL/6, derived from the strains used to generate this cohort, both of which were fully backcrossed to C57BL/6 prior to the cross.
C57BL/6-Tcra-Jtm1Tgi Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. The genetic background was C57BL/6, derived from the strains used to generate this cohort, both of which were fully backcrossed to C57BL/6 prior to the cross.
C57BL/6-Tg(Alb1-Trp53*R246S)24Sell Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was predominantly C57BL/6 (the lines crossed to produce this cohort were backcrossed to C57BL/6 before being crossed to each other) and may also contain some amount of DBA and 129S7/SvEvBrd.
C57BL/6-Tg(Alb1HBV)44Bri Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was predominantly C57BL/6 (the lines crossed to produce this cohort were backcrossed to C57BL/6 before being crossed to each other) and may also contain some amount of 129S7/SvEvBrd.
C57BL/6-Tg(IghMyc)22Bri Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Hemizygous transgenic mice heterozygous for the Trp53tm1Brd mutation on a C57BL/6 background. There may also be contributions from SJL and 129S7/SvEvBrd-Hprt+.
C57BL/6-Tg(TacLIZa)A1Jsh Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Heterozygous Trp53tm1Brd mice also carrying the Tg(TacLIZa)A1Jsh transgene on a predominantly C57BL/6 background.
C57BL/6-Tnfsf10tm1Mjs Trp53tm1Brd/+ targeted mutation (knockout) Compound mutant mice. Both knockout alleles were backcrossed to C57BL/6. Tnfsf10tm1Mjs for 10 and Trp53tm1Brd for >20 generations. These mice are the product of an intercross between those strains.
C57BL/6-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background was C57BL/6, derived from the strains used to generate this cohort, both of which were fully backcrossed to C57BL/6 prior to the cross.
C57BL/6-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was predominantly C57BL/6 (the lines crossed to produce this cohort were backcrossed to C57BL/6 before being crossed to each other) and may also contain some amount of 129S7/SvEvBrd.
C57BL/6-Trp53tm1Brd/+ targeted mutation (knockout) These mice are the product of an intercross between strains on a predominantly C57BL/6 background.
C57BL/6-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous Trp53tm1Brd mice on a 96.875% C57BL/6 background with 3.125% 129.
C57BL/6-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygouss Trp53 mice carrying the transgene on a C57BL/6 background with possible contribution from 129S7/SvEvBrd.
C57BL/6-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous Trp53 mice. Mice were N5 p53. 129/Sv- mice were backcrossed twice to C57BL/6J, twice to C57BL/6N and once to an undesignated C57BL/6 strain. There was also possible contribution from 129S7/SvEvBrd-Hprt+.
C57BL/6J-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous Trp53 mice on a C57BL/6J background with contribution from 129S7/SvEvBrd-Hprt+ from the original ES cells.
C;129-Mcm2tm1(cre/ERT2)Scpr Trp53tm1Brd/+ targeted mutation (knock-in) &
targeted mutation (knockout)
Compound mutant mice. The genetic background of these mice was a mixture of BALB/c (~50%) and "129/Sv" (~50%) (substrains(s) not specified but included 129S6/SvEvTac and 129S7/SvEvBrd-Hprt+).
C;129-Mcm2tm1(cre/ERT2)Scpr/+ Trp53tm1Brd/+ targeted mutation (knock-in) &
targeted mutation (knockout)
Compound mutant mice. The genetic background of these mice was a mixture of BALB/c (~50%) and "129/Sv" (~50%) (substrains(s) not specified but included 129S6/SvEvTac and 129S7/SvEvBrd-Hprt+).
C;129-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was a mixture of BALB/c (~50%) and "129/Sv" (~50%) (substrains(s) not specified but included 129S7/SvEvBrd-Hprt+ and likely 129S6/SvEvTac).
FVB.129S7-Trp53tm1Brd/+ congenic &
targeted mutation (knockout)
Heterozygous mice. These mice had been backcrossed to FVB. The mutation was generated in a 129S7/SvEvBrd-Hprt+ genetic background.
FVB/N-Tg(Hba-x-v-Ha-ras)TG.ACLed Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Compound mutant mice. These mice are the product of an intercross between strains on a predominantly FVB/N background.
STOCK Brca1tm2.1Cxd Trp53tm1Brd/+ targeted mutation (knockout) Mice homozygous for a hypomorphic targeted Brca1 mutation & a targeted loss-of-function Trp53 mutation. The genetic background was a mix of FVB, 129S7/SvEvBrd-Hprt+, 129S6/SvEvTac, possibly some other 129, and Black Swiss.
STOCK Brca1tm2.1Cxd/+ Trp53tm1Brd/+ targeted mutation (knockout) Mice heterozygous for a hypomorphic Brca1 targeted mutation & a targeted loss-of-function Trp53 mutation. The genetic background was a mix of FVB, 129S7/SvEvBrd-Hprt+, 129S6/SvEvTac, & possibly some 129, & Black Swiss.
STOCK Brca1tm2Cxd Tg(MMTV-cre)4Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compound mutant mice. This STOCK genetic background included FVB, C57BL/6, and 129 (at least 129S7/SvEvBrd-Hprt+ and possibly some other substrain(s)).
STOCK Prkdcscid Rag2tm1Fwa Trp53tm1Brd/+ spontaneous mutation &
targeted mutation (knockout)
Compound mutant mice. The STOCK genetic background was a mixture of ICR, C57BL/6, CB17, and "129/Sv" (including at least some 129S/SvEv-Gpi1c and some 129S7/SvEvBrd-Hprt+).
STOCK Rad51ctm1.1Sks +/+ Trp53tm1Brd targeted mutation (knockout) Compound mutant mice. The mutant alleles were on opposite copies of chromosome 11 ("trans"). This STOCK genetic background contained 129S1/SvImJ, C57BL/6, FVB/N, C3H, CD-1, 129S7/SvEvBrd, and possibly some other strain or strains.
STOCK Rad51ctm1.1Sks Trp53tm1Brd/+ + targeted mutation (knockout) Compound mutant mice. Both mutant alleles were on the same copy of chromosome 11 ("cis"). This STOCK genetic background contained 129S1/SvImJ, C57BL/6, FVB/N, C3H, CD-1, 129S7/SvEvBrd, and possibly some other strain or strains.
STOCK Tg(LPV-TAg121)2Tvd Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
These mice carry the transgene and are heterozygous for the targeted allele. The genetic background of these mice was a mixture of at least C57BL/6, DBA/2, and 129S7/SvEvBrd-Hprt+. Other strains may also have been involved.
STOCK Tg(MMTV-vHaras)SH1Led Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Compound mutant mice. This STOCK genetic background was stated to be a mixture of FVB, C57BL/6, and BALB/c. It may have also included some 129S7/SvEvBrd-Hprt+ and/or some CD-1.
STOCK Tg(NES-TVA)J12Ech Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Mice were heterozygous for the Trp53tm1Brd allele and carried the Tg(NES-TVA)J12Ech transgene. The genetic background of these animals was a mix of FVB/N, C57BL/6, 129S7/SvEvBrd-Hprt+, & an unspecified substrain of 129.
STOCK Tg(Trp53A135V)L3Ber Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
These mice are heterozygous for a targeted Trp53 and hemizygous for the "pL53-3" transgene. This STOCK genetic background was a mixture of C57BL/6, 129S7/SvEvBrd-Hprt+, and CD-1.
STOCK Tg(Wnt1)1Hev Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of this strain was a mixture of C57BL/6, SJL, and 129S7/SvEvBrd-Hprt+. It may have also included another unspecified 129/Sv substrain.
STOCK Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of this strain was a mixture of C57BL/6, SJL, and 129S7/SvEvBrd-Hprt+. It may have also included another unspecified 129/Sv substrain.
STOCK Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background was a mix of FVB, 129S7/SvEvBrd-Hprt+, some other 129, and Black Swiss.
STOCK Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. This STOCK genetic background was a mixture of C57BL/6, 129S7/SvEvBrd-Hprt+, and CD-1.
STOCK Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. This STOCK genetic background contained 129S1/SvImJ, C57BL/6, FVB/N, C3H, CD-1, 129S7/SvEvBrd, and possibly some other strain or strains.
VM.129-Trp53tm1Brd/+ congenic &
targeted mutation (knockout)
Heterozygotes. This mutation had been backcrossed onto VM. The mutant allele was originally generated in "129/Sv" and had been crossed to C57BL/6 prior to the backcrossing.
(129/Sv x C57BL/6J)F1-Trp53tm1Brd/+ hybrid &
targeted mutation (knockout)
Heterozygous mice. The genetic background of these mice was (129/Sv x C57BL/6J)F1 hybrid.
(129/Sv x M. spretus)F1-Trp53tm1Brd/+ hybrid &
targeted mutation (knockout)
Heterozygous mice. The genetic background of these mice was (129/Sv x spretus)F1 hybrid.
[not specified]-Brca1tm1Aash Tg(LGB-cre)74Acl Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous floxed Brca1, transgenic carrying, and heterozygous Trp53 mice. The genetic background of these mice was not specified but included at least 129X1/SvJ, 129S1/Sv, 129S7/SvEvBrd, CBA, and C57BL/6.
[not specified]-Brca1tm1Cxd/+ Tg(MMTV-cre)4Mam Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
The mice were heterozygous for targeted mutations of Trp53 and Brca1 and carried the Tg(MMTV-cre)4Mam transgene. The genetic background was not specified but contained 129S7/SvEvBrd-Hprt+ and 129S6/SvEvTac.
[not specified]-Brca1tm1Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice carrying a floxed & an inactivated allele of Brca1, a targeted mutation of Trp53, & the Tg(MMTV-cre)4Mam transgene. The genetic background was not specified but included some 129S7/SvEvBrd-Hprt+, & some 129S6/SvEvTac.
[not specified]-Brca1tm1Cxd/Brca1tm2Cxd Tg(Wap-cre)11738Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Transgenic mice, heterozygous for Trp53 and carrying one knockout and one conditional allele for Brca1. Background was not specified, but included contributions from C57BL/6, SJL, 129S6/SvEvTac, 129S7/SvEvBrd, and Black Swiss.
[not specified]-Brca1tm1Cxd/Brca1tm2Cxd Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout)
Mice were heterozygous for the Trp53 allele and carried both a floxed and an inactivated allele of Brca1. The genetic background was not specified but contained some 129S7/SvEvBrd-Hprt+ and some 129S6/SvEvTac.
[not specified]-Brca1tm2.1Cxd Trp53tm1Brd/+ targeted mutation (knockout) Mice were homozygous for the Brca1 allele and heterozygous for the Trp53 allele. The genetic background of these mice was not specified. It included at least some 129S6/SvEvTac and some 129S7/SvEvBrd-Hprt+.
[not specified]-Brca1tm2Cxd Pkmtm1.1Mgvh Tg(MMTV-cre)4Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Brca1, Pkm, heterozygous Trp53 mutant mice also carrying the Tg(MMTV-cre)4Mam transgene on an unspecified background with possible contribution from 129S6/SvEvTac, 129S7/SvEvBrd, and FVB.
[not specified]-Brca1tm2Cxd Tg(MMTV-cre)4Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Homozygous Brca1tm2Cxd, heterozygous Trp53tm1Brd mice also carrying the Tg(MMTV-cre)4Mam transgene on an unspecified background with possible contribution from 129S6/SvEvTac, 129S7/SvEvBrd, and FVB.
[not specified]-Brca1tm2Cxd/+ Tg(MMTV-cre)4Mam Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
The mice were heterozygous for targeted mutations of Trp53 and Brca1 and carried the Tg(MMTV-cre)4Mam transgene. The genetic background was not specified but contained some 129S7/SvEvBrd-Hprt+ and some 129S6/SvEvTac.
[not specified]-Fbxw7tm1Kin/+ Trp53tm1Brd/+ targeted mutation (knockout) Double heterozygous mice. The genetic background of these mice was not specified but included at least some 129S7/SvEvBrd-Hprt1+.
[not specified]-Krastm1Bbd/+ Tg(Cela1-tTA)#Eps Tg(tetO-cre)3Jig Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, Trp53 mutant mice carrying the Tg(Cela1-tTA)#Eps and Tg(tetO-cre)3Jig transgenes on an unspecified background with possible contributions from 129S7/SvEvBrd, 129X1/SvJ, 129S1/Sv, C57BL/6, and/or FVB/N.
[not specified]-Nf2tm2Gth +/+ Trp53tm1Brd Tg(Mpz-cre)2Brn targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Nf2tm2Gth and Trp53tm1Brd mice had each mutant allele on opposite copies of chromosome 11 (in "trans") on an unspecified background with possible contribution from 129P2/OlaHsd, FVB/N, and/or 129S7/SvEvBrd.
[not specified]-Nf2tm2Gth Tg(Mpz-cre)2Brn Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice were homozygous for the Nf2, heterozygous for the Trp53 mutant alleles, and carried the transgene. The genetic background of these mice was not specified but carried possible contributions from 129P2/OlaHsd, FVB/N, and 129S7/SvEvBrd.
[not specified]-Nf2tm2Gth Tg(Mpz-cre)3Brn Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice were homozygous for the Nf2, heterozygous for the Trp53 mutant alleles, and carried the transgene. The genetic background of these mice was not specified but carried possible contributions from 129P2/OlaHsd, FVB/N, and 129S7/SvEvBrd.
[not specified]-Nf2tm2Gth Trp53tm1Brd/+ + Tg(Mpz-cre)2Brn targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Nf2tm2Gth and Trp53tm1Brd mice with both mutant alleles on the same copy of chromosome 11 (in "cis") on an unspecified background with possible contribution from 129P2/OlaHsd, FVB/N, and/or 129S7/SvEvBrd.
[not specified]-Pinx1tm1.1Kplu/+ Trp53tm1Brd/+ targeted mutation (knockout) Double heterozygous mice. The genetic background of these mice was not specified but included at least C57BL/6J and 129S7/SvEvBrd-Hprt+.
[not specified]-Ptentm2.1Ppp/+ Tg(Tagln-cre)1Her Trp53tm1Brd/+ targeted mutation (conditional) &
transgenic
Heterozygous Pten, Trp53 mutant mice also carrying the Tagln-cre transgene on an unspecified background with possible contributions from 129S1/Sv, 129S7/SvEvBrd, C57BL/6, and/or SJL.
[not specified]-Rad54ltm1Jhjh Trp53tm1Brd/+ Xrcc5tm1Nus targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd, 129S7/SvEvBrd-Hprt+, and (129X1/SvJ x 129S1/Sv)F1-Kitl+.
[not specified]-Rb1tm1Tyj/+ Trp53tm1Brd/+ targeted mutation (knockout) Double heterozygous mice. The genetic background of these mice was not specified but included at least some 129S2/SvPas and 129S7/SvEvBrd.
[not specified]-Rb1tm2Brn Tg(Gfap-cre)2Brn Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background was not specified, but did contain contributions from FVB/N and 129S7/SvEvBrd-Hprt+.
[not specified]-Rb1tm2Brn/+ Tg(Gfap-cre)2Brn Trp53tm1Brd/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice transgenic for Cre recombinase and heterozygous for a floxed allele of Rb1 and a targeted mutation of Trp53. The genetic background was not specified, but did contain contributions from FVB/N and 129S7/SvEvBrd-Hprt+.
[not specified]-Sirt1tm1.1Cxd/+ Trp53tm1Brd/+ targeted mutation (knockout) Double heterozygous mice. The genetic background was not specified but may have included 129S6/SvEvTac, 129S7/SvEvBrd-Hprt1+, FVB/N, and C57BL/6 or Black Swiss and possibly some other strain or strains.
[not specified]-Stk11tm1Mmt/+ Trp53tm1Brd/+ targeted mutation (knockout) Double heterozygous mice. The genetic background of these mice was not specified but included at least some 129S7/SvEvBrd-Hprt+ and some 129X1/SvJ.
[not specified]-Tg(GFAP-SRC)#Aag Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Mice were heterozgyous for the Trp53 allele and carried the transgene. The genetic background of this strain was not specified. It included at least C57BL/6J, C3H, and 129S7/SvEvBrd-Hprt+.
[not specified]-Tg(Nes-cre)1Kln Trp53tm1Brd/+ Xrcc4tm2Fwa/+ targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice carried the transgene and were heterozygous for both mutant alleles. Genetic background not specified but included at least 129S6/SvEvTac, 129S7/SvEvBrd, C57BL/6, and SJL.
[not specified]-Tg(Nes-cre)1Kln Trp53tm1Brd/+ Xrcc4tm2Fwa/Xrcc4tm2.1Fwa targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Mice carried the transgene, were heterozygous for the Trp53 mutant allele, & had one allele each of the conditional & KO alleles for Xrcc4. Genetic background not specified but included at least 129S6/SvEvTac, 129S7/SvEvBrd, C57BL/6, & SJL.
[not specified]-Tg(Rbp3-HPVE7)1Jjw Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Transgenic mice, heterozygous for the Trp53tm1Brd allele. The genetic background of these mice was not specified, but included contributions from C57BL/6, BALB/c, and 129S7/SvEvBrd-Hprt+.
[not specified]-Tg(S100b-v-erbB)4496Waw Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Transgenic mice, heterozygous for a Trp53 mutation. Background was refered to as outbred and includes contributions from C57BL/6J, DBA/2J, FVB/N, and 129S7/SvEvBrd-Hprt+.
[not specified]-Tg(SV40-NRAS*G12D)1Sco Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Heterozygous Trp53 mutant mice also transgenic and on an unspecified background with possible contributions from SJL and/or 129S7/SvEvBrd-Hprt1+.
[not specified]-Tg(Tagln-cre)1Her Trp53tm1Brd/+ targeted mutation (conditional) &
transgenic
Heterozygous Trp53 mice also carrying the Tagln-cre transgene on an unspecified background with possible contributions from 129S1/Sv, 129S7/SvEvBrd, C57BL/6, and/or SJL.
[not specified]-Tg(Th-MYCN)#Waw Trp53tm1Brd/+ targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified. It contained 129S7/SvEvBrd-Hprt+ and either C57BL/6J, or FVB/N, or a C57BL/6J x BALB/c combination. (#-founder number not specified)
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Mice heterozygous for a targeted mutation of Trp53. The genetic background was not specified but contained some 129S7/SvEvBrd-Hprt+.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. Background was not specified, but includes contributions from 129S7/SvEvBrd-Hprt+ and either Black Swiss or C57BL/6 as background of original founder mouse.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was not specified, but included contributions from C57BL/6, BALB/c, and 129S7/SvEvBrd-Hprt+.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was either mixed "129/Sv" (substrain not specified) and Mus spretus or mixed "129/Sv" (substrain not specified) and C57BL/6J.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was not specified but included at least some 129S7/SvEvBrd-Hprt1+.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background was not specified but may have included 129S6/SvEvTac, 129S7/SvEvBrd-Hprt1+, FVB/N, and C57BL/6 or Black Swiss and possibly some other strain or strains.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was not specified but included at least C57BL/6, 129X1/SvJ, and likely some 129S7/SvEvBrd-Hprt+
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous mice. The genetic background of these mice was not specified but included at least C57BL/6J and 129S7/SvEvBrd-Hprt+.
[not specified]-Trp53tm1Brd/+ targeted mutation (knockout) Heterozygous Trp53tm1Brd mice on an unspecified background. Mice were purchased from Taconic and had a genetic background that was either congenic onto C57BL/6 or mixed C57BL/6 and 129.
[not specified]-Trp53tm1Brd/+ Trp53bp2tm1Cdlo/+ targeted mutation (knockout) Double heterozygous mice. The genetic background of these mice was not specified but included at least C57BL/6, 129X1/SvJ, and 129S7/SvEvBrd-Hprt+