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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Strain Search Results  
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31 matching items displayed.
Strain Name Strain Type Strain Notes
129S4/SvJae-Krastm3Tyj/+ targeted mutation (knock-in) Mice heterozygous for a targeted mutation of Kras. Spontaneous somatic recombination leads to the expression of an activated oncogenic KRAS protein. The genetic background was 129S4/SvJae.
B6;129S-Krastm3Tyj/+ targeted mutation (knock-in) Mice were on a mixed C57BL/6 and 129S background. Mice were heterozygous for the Krastm3Tyj mutation.
B6;129S-Krastm3Tyj/+ Uba7tm1Dez targeted mutation (conditional) &
targeted mutation (knock-in)
Mice were on a mixed C57BL/6 and 129S background. Mice were heterozygous for the Krastm3Tyj and homozygous for the Uba7tm1Dez mutations.
B6;129S4-Krastm3Tyj/+ targeted mutation (knock-in) Heterozygous mice. The genetic background of these mice was 50% C57BL/6 and 50% 129S4/SvJae. [They were reported to be F1 but the direction of the cross was not given.]
C57BL/6J-Krastm3Tyj/+ targeted mutation (knock-in) Heterozygous Kras mutant mice on a predominantly C57BL/6J background with possible contribution from 129S4/SvJae.
C57BL/6J-Krastm3Tyj/+ Mir301tm1Yoli targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Kras, homozygous Mir301 mutant mice on a predominantly C57BL/6J background with possible contribution from 129S4/SvJae.
FVB-Krastm3Tyj/+ targeted mutation (knock-in) Heterozygous Kras mice on an FVB background with contribution from 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
FVB-Krastm3Tyj/+ Usp18tm1Dez targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Kras, homozygous Usp18 mice on an FVB background with contribution from 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
FVB-Krastm3Tyj/+ Usp18tm1Dez/+ targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Kras, Usp18 mice on an FVB background with contribution from 129X1/SvJ, 129S1/Sv, and 129S4/SvJae.
[not specified]-Cdkn2atm4Rdp Krastm3Tyj/+ Ikbkbtm2Mka Tg(Pdx1-cre/Esr1*)#Dam targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Heterozygous Kras, homozygous Cdkn2a, Ikbkb, transgenic mice on an unspecified genetic background with contributions from at least 129S/SvEv, 129S2/SvPas, C57BL/6, and CBA.
[not specified]-Cdkn2atm4Rdp Krastm3Tyj/+ Tg(Pdx1-cre/Esr1*)#Dam targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Heterozygous Kras, homozygous Cdkn2a, transgenic mice on an unspecified genetic background with contributions from at least 129S2/SvPas, C57BL/6, and CBA.
[not specified]-Gt(ROSA)26Sortm1(cre/ERT2)Alj Igs2tm1(ACTB-EGFP,-tdTomato)Luo/Igs2tm2(ACTB-tdTomato,-EGFP)Luo Krastm3Tyj/+ targeted mutation (knock-in) &
targeted mutation (other)
Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae, and also 129X1/SvJ and/or 129S1/Sv. There may have been other strain contributions.
[not specified]-Gt(ROSA)26Sortm1(cre/ERT2)Alj Igs2tm1(ACTB-EGFP,-tdTomato)Luo/Igs2tm2(ACTB-tdTomato,-EGFP)Luo Krastm3Tyj/+ Trp53tm1Tyj/+ targeted mutation (knock-in) &
targeted mutation (knockout) &
targeted mutation (other)
Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae, 129S2/SvPas, and also 129X1/SvJ and/or 129S1/Sv. There may have been other strain contributions.
[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ gene trapped &
targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt15, ROSA, Kras mice on an unspecified background with possible contributions from 129S6/SvEvTac, C57BL/6J, SJL/J, C57BL/6NCrl, 129P2/OlaHsd and 129S4/SvJae.
[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ Ptentm1Hwu/+ gene trapped &
targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt15, ROSA, Kras, Pten mice on an unspecified background with possible contributions from 129S6/SvEvTac, C57BL/6J, SJL/J, C57BL/6NCrl, 129P2/OlaHsd and 129S4/SvJae.
[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ Ptgs2tm1Hahe Trp53tm1Brn gene trapped &
targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt15, ROSA, Kras, homozygous Trp53, Ptgs2 mice on an unspecified background with possible contributions from 129S6/SvEvTac, C57BL/6J, SJL/J, C57BL/6NCrl, 129P2/OlaHsd and 129S4/SvJae.
[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ Trp53tm1Brn gene trapped &
targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt15, ROSA, Kras, homozygous Trp53 mice on an unspecified background with possible contributions from 129S6/SvEvTac, C57BL/6J, SJL/J, C57BL/6NCrl, 129P2/OlaHsd and 129S4/SvJae.
[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ Trp53tm1Brn/+ gene trapped &
targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Krt5, ROSA, Trp53, Kras mice on an unspecified background with possible contributions from 129S6/SvEvTac, C57BL/6NCrl, 129P2/OlaHsd and 129S4/SvJae.
[not specified]-Krastm3Tyj/+ targeted mutation (knock-in) Heterozygous mice on an unspecified background that contained contributions from at least C57BL/6 and 129S2/SvPas.
[not specified]-Krastm3Tyj/+ targeted mutation (knock-in) Heterozygous mice. The genetic background was not specified but included contributions from at least C57BL/6J and an unspecified substrain of 129.
[not specified]-Krastm3Tyj/+ targeted mutation (knock-in) Heterozygous mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae. There may have been other strain contributions.
[not specified]-Krastm3Tyj/+ Ikbkbtm2Mka Tg(Pdx1-cre/Esr1*)#Dam targeted mutation (conditional) &
targeted mutation (knock-in) &
transgenic
Heterozygous Kras, homozygous Ikbkb, transgenic mice on an unspecified genetic background with contributions from at least 129S/SvEv, 129S2/SvPas, C57BL/6, and CBA.
[not specified]-Krastm3Tyj/+ Mmp10tm1Lex targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Kras, homozygous Mmp10 mice. The genetic background was not specified but included contributions from at least C57BL/6J and an unspecified substrain of 129.
[not specified]-Krastm3Tyj/+ Ptf1atm1.1(cre)Cvw/+ Trp53tm2Tyj/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Ptf1a, Kras, Trp53 mutant mice on an unspecified background with possible contribution from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, and 129P2/OlaHsd.
[not specified]-Krastm3Tyj/+ Ptf1atm1.1(cre)Cvw/+ Trp53tm2Tyj/+ Yap1tm1.1Dupa targeted mutation (conditional) &
targeted mutation (knock-in)
Homozygous Yap1, heterozygous Ptf1a, Kras, Trp53 mice on an unspecified background with possible contribution from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, and 129P2/OlaHsd.
[not specified]-Krastm3Tyj/+ Ptf1atm1.1(cre)Cvw/+ Yap1tm1.1Dupa targeted mutation (conditional) &
targeted mutation (knock-in)
Homozygous Yap1, heterozygous Ptf1a, Kras mutant mice on an unspecified background with possible contribution from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, and 129P2/OlaHsd.
[not specified]-Krastm3Tyj/+ Ptf1atm1.1(cre)Cvw/+ Yap?/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Ptf1a, Kras, Yap mutant mice on an unspecified background with possible contribution from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, & 129P2/OlaHsd. Yap alleles could be either mutant/wild-type or homozygous wild-type.
[not specified]-Krastm3Tyj/+ Tg(Fabp2-PRKCI*K274W)#Flds targeted mutation (knock-in) &
transgenic
Heterozygous, transgenic mice on an unspecified background that contained contributions from at least C57BL/6 and 129S2/SvPas.
[not specified]-Krastm3Tyj/+ Tg(Pdx1-cre/Esr1*)#Dam targeted mutation (knock-in) &
transgenic
Heterozygous Kras and transgenic mice on an unspecified genetic background with contributions from at least 129S2/SvPas, C57BL/6, and CBA.
[not specified]-Krastm3Tyj/+ Trp53tm2Tyj/+ Yap1tm1.1Dupa targeted mutation (conditional) &
targeted mutation (knock-in)
Homozygous Yap1, heterozygous Kras, Trp53 mutant mice on an unspecified background with possible contribution from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, and 129P2/OlaHsd.
[not specified]-Krastm3Tyj/+ Trp53tm2Tyj/+ Yap1tm1.1Dupa/+ targeted mutation (conditional) &
targeted mutation (knock-in)
Heterozygous Kras, Trp53, Yap mutant mice on an unspecified background with possible contribution from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, and 129P2/OlaHsd.