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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Strain Search Results  
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18 matching items displayed.
Strain Name Strain Type Strain Notes
129/Sv-Krastm2Tyj/+ targeted mutation (knock-in) Heterozygous Krastm2Tyj mice on a 129/Sv background with possible contribution from 129S2/SvPas.
129S-Krastm2Tyj/+ targeted mutation (knock-in) Heterozygotes. The genetic background of these mice was stated to be greater than 90% 129/Sv. The other strains involved in this background were not specified.
129S-Krastm2Tyj/+ Trp53tm1Glo/+ targeted mutation (knock-in) Double heterozygotes. The genetic background of these mice was stated to be greater than 90% 129/Sv. The other strains involved in this background were not specified.
129S-Krastm2Tyj/+ Trp53tm1Tyj/+ targeted mutation (knock-in) &
targeted mutation (knockout)
Double heterozygotes. The genetic background of these mice was stated to be greater than 90% 129/Sv. The other strains involved in this background were not specified.
129S2/SvPas-Krastm2Tyj/+ targeted mutation (knock-in) Mice heterozygous for a targeted mutation of Kras. Spontaneous somatic recombination leads to the expression of an activated oncogenic KRAS protein. The genetic background was 129S2/SvPas.
B6;129S2-Krastm2Tyj/+ targeted mutation (knock-in) Mice heterozygous for a targeted mutation of Kras ("K-rasLA1"). Spontaneous somatic recombination leads to the expression of an activated oncogenic KRAS protein. The genetic background was a mix of C57BL/6 and 129S2/SvPas.
C57BL/6-Krastm2Tyj/+ targeted mutation (knock-in) Heterozygous mice on a >95% C57BL/6 background that may also contain contributions from 129S2/SvPas. Kras knock-in only expressed after intrachromosomal recombination, unrecombined allele expresses no protein.
C57BL/6-Krastm2Tyj/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Compound mutant mice on a >95% C57BL/6 background that may also contain contributions from 129S2/SvPas. Kras knock-in only expressed after intrachromosomal recombination, unrecombined allele expresses no protein.
C57BL/6-Krastm2Tyj/+ Trp53tm3.1Glo targeted mutation (knock-in) Compound mutant mice on a >95% C57BL/6 background that may also contain contributions from 129S2/SvPas and 129S7/SvEvBrd. Kras knock-in only expressed after intrachromosomal recombination, unrecombined allele expresses no protein.
STOCK Krastm2Tyj/+ targeted mutation (knock-in) Heterozygous mice. This STOCK genetic background was a mixture of C57BL/6J, "129/SvJ", and BALB/cJ.
STOCK Krastm2Tyj/+ Tg(Actb-Mdm4)15Glo targeted mutation (knock-in) &
transgenic
Compound mutant mice. This STOCK genetic background was a mixture of C57BL/6J, "129/SvJ", and BALB/cJ.
STOCK Krastm2Tyj/+ Tg(Actb-Mdm4)6Glo targeted mutation (knock-in) &
transgenic
Compound mutant mice. This STOCK genetic background was a mixture of C57BL/6J, "129/SvJ", and BALB/cJ.
STOCK Krastm2Tyj/+ Trim62tm1Akil targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Krastm2Tyj, homozygous Trim62tm1Akil mice on mixed 129/Sv, C57BL/6J, and BALB/c background with possible contribution from 129S2/SvPas and/or 129/SvEv.
STOCK Krastm2Tyj/+ Trim62tm1Akil/+ targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Krastm2Tyj, Trim62tm1Akil mice on mixed 129/Sv, C57BL/6J, and BALB/c background with possible contribution from 129S2/SvPas and/or 129/SvEv.
STOCK Krastm2Tyj/+ Trim62tm1Akil/? targeted mutation (knock-in) &
targeted mutation (knockout)
Heterozygous Kras mutant mice carrying either one or two Trim62tm1Akil alleles on mixed 129/Sv, C57BL/6J, and BALB/c background with possible contribution from 129S2/SvPas and/or 129/SvEv.
[not specified]-Krastm2Tyj/+ targeted mutation (knock-in) Heterozygous mice ("K-rasLA1"). The genetic background of these mice was not specified. It contained some 129S2/SvPas and possibly some C57BL/6.
[not specified]-Krastm2Tyj/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Kras conditional mutant heterozygous and Trp53 KO homozygous mice. Spontaneous somatic recombination leads to the expression of an activated oncogenic KRAS protein. The genetic background was not specified.
[not specified]-Krastm2Tyj/+ Trp53tm1Tyj/+ targeted mutation (knock-in) &
targeted mutation (knockout)
Mice heterozygous for targeted mutations of Kras and Trp53. Spontaneous somatic recombination leads to the expression of an activated oncogenic KRAS protein. The genetic background was not specified.