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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Strain Search Results  
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220 matching items displayed.
Strain Name Strain Type Strain Notes
129-Pou2f1tm1Shrp/+ Trp53tm1Tyj targeted mutation (knockout) &
targeted mutation (other)
Compound mutant mice. The genetic background of these mice was stated to be 129. The substrain(s) were not specified but included at least some 129S2/SvPas and some 129S4/SvJae.
129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was stated to be 129 (substrain(s) not specified but included at least some 129S2/SvPas and possibly some 129S4/SvJae).
129-Trp53tm1Tyj/J targeted mutation (knockout) Homozygous mice
129/Sv-Hoxa5tm1Rob Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background of these mice was "129/Sv" (substrains unspecified but included at least 129S/SvEv and 129S2/SvPas).
129/Sv-Hoxa5tm1Rob/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was "129/Sv" (substrains unspecified but included at least 129S/SvEv and 129S2/SvPas).
129/Sv-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was "129/Sv" (substrains unspecified but included at least 129S2/SvPas and likely 129S/SvEv).
129;B6-Apc Min/+Trp53tm1Tyj chemically induced mutation &
targeted mutation (knockout)
Heterozygous Min, homozygous Trp53 mice on a mixed 129, B6 background with contribution from C57BL/6J, 129S2/SvPas and 129P2/OlaHsd.
129;B6-Apc Min/+Trp53tm1Tyj Zfp148Gt(XB878)Byg/+ chemically induced mutation &
gene trapped &
targeted mutation (knockout)
Heterozygous Min, Zfp148, homozygous Trp53 mice on a mixed 129, B6 background with contribution from C57BL/6J, 129S2/SvPas and 129P2/OlaHsd.
129S-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The gentic background of these mice was stated to be 129S1/SvImJ. It also included some 129S2/SvPas and likely some 129S4/SvJae.
129S-Trp53tm1Tyj Trp53bp1Gt(OST94324)Lex gene trapped &
targeted mutation (knockout)
Mice homozygous for Trp53tm1Tyj and Trp53bp1Gt(OST94324)Lex. The background included 129S2/SvPas, 129S5/SvEvBrd, and may include contributions from other strains.
129S-Trp53tm1Tyj Trp53bp1Gt(OST94324)Lex/+ gene trapped &
targeted mutation (knockout)
Mice homozygous for Trp53tm1Tyj and heterozygous for Trp53bp1Gt(OST94324)Lex. The background included 129S2/SvPas, 129S5/SvEvBrd, and may include contributions from other strains.
129S-Trp53tm1Tyj Trp73tm1Fmc targeted mutation (knockout) Compound mutant mice. The gentic background of these mice was stated to be 129S1/SvImJ. It also included some 129S2/SvPas and some 129S4/SvJae.
129S-Trp53tm1Tyj Trp73tm1Fmc/+ targeted mutation (knockout) Compound mutant mice. The gentic background of these mice was stated to be 129S1/SvImJ. It also included some 129S2/SvPas and some 129S4/SvJae.
129S1/SvImJ-Rb1tm1Tyj/+ Trp53tm1Tyj targeted mutation (knockout) Mice are heterozygous for both the Rb1tm1Tyj allele and homozygous for the Trp53tm1Tyj allele.
129S2-Trp53tm1Tyj targeted mutation (knockout) Mice homozygous for Trp53tm1Tyj. The background included 129S2/SvPas and may include contributions from other strains.
B10;B6-Dmdmdx Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53, female homozygous, male hemizygous Dmd mice were generated by crossing B6.129S2-Trp53>tm1Tyj/J (stock# 002101) and C57BL/10ScSn-Dmdmdx/J (stock# 001801) strains.
B10;B6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice were generated by crossing B6.129S2-Trp53>tm1Tyj/J (stock# 002101) and C57BL/10ScSn-Dmdmdx/J (stock# 001801) strains.
B6.129-Apctm1Rak/+ Trp53tm1Tyj congenic &
targeted mutation (knockout)
Compound mutant mice. These mice are the product of an intercross between strains on a predominantly C57BL/6JIco background where the mice were subsequently backcrossed to C57BL/6JIco.
B6.129S2-Trp53tm1Tyj congenic &
targeted mutation (knockout)
Homozygous mice. The mutant allele had been backcrossed onto C57BL/6 and contained some contribution from 129S2/SvPas.
B6.129S2-Trp53tm1Tyj/J congenic &
targeted mutation (knockout)
Homozygous mice
B6;129-Cdkn2atm1Cjs Mdm2tm1Glo Trp53tm1Tyj targeted mutation (knockout) Homozygous Cdkn2atm1Cjs, Mdm2tm1Glo, and Trp53tm1Tyj mice on a mixed C57BL/6J, 129/Sv background with possible contributions from 129X1/SvJ, 129S7/SvEvBrd-Hprt+, and/or 129S2/SvPas.
B6;129-Cdkn2atm1Cjs Mdm2tm1Glo/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
B6;129-Cdkn2atm1Cjs Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
B6;129-Cdkn2atm1Cjs Trp53tm1Tyj targeted mutation (knockout) Homozygous Cdkn2atm1Cjs and Trp53tm1Tyj mice on a mixed C57BL/6J, 129/Sv background with possible contributions from 129X1/SvJ, 129S7/SvEvBrd-Hprt+, and/or 129S2/SvPas.
B6;129-Cdkn2atm1Cjs/+ Mdm2tm1Glo/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
B6;129-Cdkn2atm1Cjs/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
B6;129-Cdkn2ctm1Bbd Cdkn2dtm1Maro Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for the Cdkn2c, Cdkn2d, and Trp53 alleles. The genetic background was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Cdkn2ctm1Bbd Cdkn2dtm1Maro/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Cdkn2ctm1Bbd Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Cdkn2ctm1Bbd/+ Cdkn2dtm1Maro Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Cdkn2ctm1Bbd/+ Cdkn2dtm1Maro/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Cdkn2ctm1Bbd/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd and 129S2/SvPas.
B6;129-Cdkn2dtm1Maro Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Dclre1ctm1Fwa Trp53tm1Tyj targeted mutation (hypomorph) &
targeted mutation (knockout)
Homozygous mice in a 75% 129/Sv, 25% C57BL/6 background. 129/Sv contribution was from multiple substrains including 129S6/SvEvTac and 129S2/SvPas
B6;129-Dclre1ctm1Jsek Trp53tm1Tyj targeted mutation (hypomorph) &
targeted mutation (knockout)
Homozygous mice in a 75% 129/Sv, 25% C57BL/6 background. 129/Sv contribution was from multiple substrains including 129X1/SvJ, 129S1/Sv and 129S2/SvPas
B6;129-Fn1tm1Hyn/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 x 129/Sv (substrain not specified but included at least 129S2/SvPas).
B6;129-Gfaptm1Pkny Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for both the Gfaptm1Pkny and the Trp53tm1Tyj
B6;129-Hace1tm1Pngr Trp53tm1Tyj targeted mutation (knockout) These mice were homozygous for both mutant alleles. The genetic background of these mice was a mixture of C57BL/6, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Hace1tm1Pngr/+ Trp53tm1Tyj targeted mutation (knockout) These mice were heterozygous for the Hace1 and homozygous for the Trp53 mutant alleles. The genetic background of these mice was a mixture of C57BL/6, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Itga5tm1Hyn/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 x 129/Sv (substrain not specified but included at least 129S2/SvPas).
B6;129-Lig4tm1Fwa Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and 129 (substrain(s) not specified but included at least some 129P2/OlaHsd and some 129S2/SvPas).
B6;129-Mdm2tm1Glo Trp53tm1Tyj targeted mutation (knockout) Homozygous Mdm2tm1Glo and Trp53tm1Tyj mice on a mixed C57BL/6J, 129/Sv background with possible contributions from 129X1/SvJ, 129S7/SvEvBrd-Hprt+, and/or 129S2/SvPas.
B6;129-Mdm2tm1Glo/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
B6;129-Nf1tm1Fcr/+ Trp53tm1Tyj targeted mutation (knockout) Mice heterozygous for a gene-targeted mutant allele of Nf1 and homozygous for a disrupted Trp53 gene. The genetic background was a mix of C57BL/6 and 129/Sv (a mixture of 129S2/SvPas, 129S4/SvJae, and 129S6/SvEv).
B6;129-Parp1tm1Jmdm Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (including 129S2/SvPas and possibly some other substrain(s)).
B6;129-Ptch1tm1Mps/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129P2/OlaHsd, 129S2/SvPas, 129X1/SvJ, and 129S1/Sv.
B6;129-Rb1tm1Tyj/+ Trp53tm1Tyj targeted mutation (knockout) Mice were heterozygous for Rb1tm1Tyj and homozygous for Trp53tm1Tyj. The genetic background of these mice is referred to as 129 X C57BL/6 and involves C57BL/6, 129S2/SvPas, and an unspecified substrain of 129/Sv.
B6;129-Rpa1tm1Wed/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Compound mutant mice. The genetic background of these mice was predominantly a mixture of C57BL/6 and 129S4/SvJae. It also included some 129S2/SvPas and likely some unspecified 129/Sv and some SJL.
B6;129-SufuGt(XB699)Byg/+ Trp53tm1Tyj gene trapped &
targeted mutation (knockout)
Compound mutant mice. The genetic background of these mice was a mixture of C57BL/6, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Thbs1tm1Hyn Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for both Thbs1 and Trp53 mutant alleles. The genetic background of these mice is a mixture of C57BL/6J and 129/Sv (at least 129S2/SvPas from the ES cells, and possibly some other 129/Sv substrain).
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice is a mixture of C57BL/6J and 129/Sv (at least 129S2/SvPas from the ES cells and possibly some other 129/Sv substrain).
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6, 129X1/SvJ, 129S1/Sv-p+ Tyr+ Kitl+, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Trp53tm1Tyj targeted mutation (knockout) Mice homozygous for Trp53 knockout. Mice were referred to as (C57BL/6 X 129)F1. Background included contributions from C57BL/6, 129S2/SvPas, and possibly some other substrain of 129/Sv.
B6;129-Trp53tm1Tyj targeted mutation (knockout) Mice homozygous for Trp53 knockout, Pten wildtype. Background includes contributions from C57BL/6, 129S1/SvImJ, 129S2/SvPas, and possibly other substrains of 129/Sv.
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and '129' (unspecified substrains including at least 129P2/OlaHsd and 129S2/SvPas).
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6, 129P2/OlaHsd, and 129S2/SvPas.
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice in a 75% 129/Sv, 25% C57BL/6 background. 129/Sv contribution was from multiple substrains.
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 (64%) and 129/Sv (36%). The "129/Sv" was a combination of at least 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and 129X1/SvJ.
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 x 129/Sv (substrain not specified but included at least 129S2/SvPas).
B6;129-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (including 129S2/SvPas and possibly some other substrain(s)).
B6;129S-ApcMin/+ Trp53tm1Tyj chemically induced mutation &
targeted mutation (knockout)
Mice were heterozygous for the ApcMin mutation and homozygous for the Trp53tm1Tyj mutation. The genetic background of these mice is a mixture of C57BL/6J, 129S2/SvPas, and 129S4/SvJae.
B6;129S-Cdk2tm1Kald Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and 129S (including the 129S1/Sv-Oca2+ Tyr+ Kitl+, 129S2/SvPas, and 129S1/SvImJ substrains).
B6;129S-Dph1tm2Bhr/+ Trp53tm1Tyj targeted mutation (knockout) Heterozygous Dph1 mutant and homozygous Trp53 mutant. The genetic background of these mice was a mixture of predominantly C57BL/6 and "129/SvEv" (substrain not specified), and also carried some 129S4/SvJae and some 129S2/SvPas.
B6;129S-Mdm2tm1Glo Trp53tm1Tyj targeted mutation (knockout) Mice are homozygous for Mdm2tm1Glo and homozygous for Trp53tm1Tyj. The genetic background of this strain is a mixture of C57BL/6J, 129S7/SvEvBrd-Hprt+, and 129S2/SvPas.
B6;129S-Mdm2tm1Glo/+ Trp53tm1Tyj targeted mutation (knockout) Mice are heterozygous for Mdm2tm1Glo and homozygous for Trp53tm1Tyj. The genetic background of this strain is a mixture of C57BL/6J, 129S7/SvEvBrd-Hprt+, and 129S2/SvPas.
B6;129S-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of this strain is a mixture of C57BL/6 and 129S/Sv.
B6;129S-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of predominantly C57BL/6 and "129/SvEv" (substrain not specified), and also carried some 129S2/SvPas.
B6;129S-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and 129S (including the 129S2/SvPas, 129S1/SvImJ, and possibly 129S1/Sv-Oca2+ Tyr+ Kitl+ substrains).
B6;129S-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly a mixture of C57BL/6 and 129S4/SvJae. It also included some 129S2/SvPas.
B6;129S2-Rb1tm1Tyj/+ Trp53tm1Tyj targeted mutation (knockout) Mice are heterozygous for Rb1tm1Tyj and homozygous for Trp53tm1Tyj. This strain was generated by crossing 2 targeted mutant strains. The genetic background of this strain is a mixture of C57BL/6 and 129S2/SvPas.
B6;129S2-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of this strain is a mixture of C57BL/6 and 129S2/SvPas.
B6;129S4-Hic1tm1Sbb/+ Trp53tm1Tyj targeted mutation (knockout) The genetic background of these mice was a mix of C57BL/6 and 129S4/SvJae. MIce were heterozygous for Hic1tm1Sbb and homozygous for Trp53tm1Tyj.
B6;129S4-Trp53tm1Tyj targeted mutation (knockout) The genetic background of these mice was a mix of C57BL/6 and 129S4/SvJae. MIce were homozygous for the Trp53tm1Tyj mutation.
B6;129S6-Krastm1Dsa/+ Tg(Pdx1-flpo)#Dsa Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Heterozygous Kras, homozygous Trp53 mutant mice also carrying the transgene on a mixed C57BL/6, 129S6/SvEv background with contribution from 129S6/SvEvTac and 129S2/SvPas from the original ES cells.
B6;129X1-Gt(ROSA)26Sortm1(cre/ERT2)Tyj Tacc3tm1.1Tno/+ Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout)
Homozygous Trp53, heterozygous Tacc3 mice also carrying the cre/ERT2 knock-in on a mixed C57BL/6, 129X1/SvJ background. Mice also may have contributions from 129S2/SvPas and 129S4/SvJae.
B6;129X1-Gt(ROSA)26Sortm1(cre/ERT2)Tyj Tacc3tm1.1Tno/Tacc3tm1.2Tno Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knock-in) &
targeted mutation (knockout)
Homozygous Trp53, heterozygous Tacc3 mice also carrying the cre/ERT2 knock-in on a mixed C57BL/6, 129X1/SvJ background. Mice also may have contributions from 129S2/SvPas and 129S4/SvJae.
BALB/c-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly BALB/c (via intercrossing of congenic strains) and likely included some amount of 129S2/SvPas and possibly some 129S6/SvEvTac and/or C57BL/6J.
BALB/c-Trp53tm1Tyj Trp53bp2tm1Xlu/+ targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was predominantly BALB/c (via intercrossing of congenic strains) and likely included some amount of 129S2/SvPas, 129S6/SvEvTac, and possibly some C57BL/6J.
BALB/cJ-Mapk8tm1Flv Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. This cohort was generated by crossing congenic BALB/cJ mice carrying each of the mutations. Genetic background also contained some 129S1/Sv-Oca2+ Tyr+ Kitl+ & some 129S2/SvPas.
BALB/cJ-Mapk9tm1Flv Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. This cohort was generated by crossing congenic BALB/cJ mice carrying each of the mutations. The genetic background also contained some 129S2/SvPas.
BALB/cJ-Tg(Actb-Mdm4)15Glo Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was predominantly BALB/cJ. This cohort was generated by breeding two BALB/cJ congenic strains.
BALB/cJ-Tg(Actb-Mdm4,-lacZ)1Glo Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was predominantly BALB/cJ. This cohort was generated by breeding two BALB/cJ congenic strains.
BALB/cJ-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly BALB/cJ. It also contained some 129S2/SvPas and possibly some other strain(s).
BALB/cJ-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly BALB/cJ. This cohort was generated by breeding two BALB/cJ congenic strains.
C.129S2(B6)-Trp53tm1Tyj/J congenic &
targeted mutation (knockout)
Congenic mice homozygous for a targeted mutation of Trp53. Mice carrying the Trp53tm1Tyj were backcrossed to BALB/cJ mice.
C.129S2-Trp53tm1Tyj congenic &
targeted mutation (knockout)
Homozygous mice. The genetic background of these mice is predominantly BALB/cMed with some contribution from 129S2/SvPas and C57BL/6. Mice were backcrossed from C57BL/6x129/Sv background for at least 9 generations to BALB/c.
C.129S2-Trp53tm1Tyj congenic &
targeted mutation (knockout)
Homozygous mice. The mutation had been backcrossed onto a BALB/cJ genetic background. The mutation was generated in a 129S2/SvPas genetic background.
C57BL/6-Atf3tm1Dron Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was predominantly C57BL/6 including at least some C57BL/6J. It also included some 129X1/SvJ and some 129S2/SvPas.
C57BL/6-Bcl2l11tm1.1Ast Rag1tm1Mom Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53, Bcl2l11, Rag1 mutant mice on a predominantly C57BL/6 background with possible contribution from 129S2/SvPas, 129S7/SvEvBrd, 129S1/Sv, and/or other strain(s).
C57BL/6-Bcl2l11tm1.1Ast Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53, Bcl2l11 mutant mice on a predominantly C57BL/6 background with possible contribution from 129S2/SvPas, 129S1/Sv, and/or other strain(s).
C57BL/6-Bcl2l11tm1.1Ast/+ Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53, heterozygous Bcl2l11 mutant mice on a predominantly C57BL/6 background with possible contribution from 129S2/SvPas, 129S1/Sv, and/or other strain(s).
C57BL/6-Bmftm1.1Ast Trp53tm1Tyj targeted mutation (knockout) Homozygous Bmf, Trp53 mutant mice on a predominantly C57BL/6 background with possible contribution of 129S2/SvPas and possibly some other strain(s).
C57BL/6-Bmftm1.1Ast/+ Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53, heterozygous Bmf mutant mice on a predominantly C57BL/6 background with possible contribution of 129S2/SvPas and possibly some other strain(s).
C57BL/6-Cdkn1atm1Tyj Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. These mice were generated by crossing targeted mutant mice on a C57BL/6 genetic background.
C57BL/6-Cdkn2atm1Cjs Tg(RIP1-Tag)2Dh Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Compound mutant mice. These mice were generated by crossing strains that had previously been fully backcrossed onto C57BL/6. The genetic background may also include some DBA/2J and/or some 129X1/SvJ and/or some 129S2/SvPas.
C57BL/6-Cul9tm1.2Yxi Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The strains crossed to generate this cohort had been backcrossed to C57BL/6 prior to that cross. The genetic background may also include some 129S2/SvPas, 129P2/OlaHsd, and/or FVB/N.
C57BL/6-Cul9tm1.2Yxi/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The strains crossed to generate this cohort had been backcrossed to C57BL/6 prior to that cross. The genetic background may also include some 129S2/SvPas, 129P2/OlaHsd, and/or FVB/N.
C57BL/6-Egr1tm1Jmi/+ Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53tm1Brd, heterozygous Egr1tm1Jmi mice on a C57BL/6 background with possible contributions from 129S2/SvPas and an unspecified 129 substrain.
C57BL/6-Hsf4tm1Miv Trp53tm1Tyj targeted mutation (knockout) &
targeted mutation (other)
Compound mutant mice. The genetic background of these mice was predominantly C57BL/6, generated by crossing strains each on that backgound. There was likely some contribution from 129S2/SvPas.
C57BL/6-Krastm2Tyj/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Compound mutant mice on a >95% C57BL/6 background that may also contain contributions from 129S2/SvPas. Kras knock-in only expressed after intrachromosomal recombination, unrecombined allele expresses no protein.
C57BL/6-Mdm2tm1Glo Mdm4tm1Glo Trp53tm1Tyj targeted mutation (knockout) Triple homozygous mutant mice. These mice are the product of intercrosses between strains on a predominantly C57BL/6 background.
C57BL/6-Msh2tm1Rak Trp53tm1Tyj targeted mutation (knockout) Homozygous Msh2tm1Rak, Trp53tm1Tyj mice on a C57BL/6 background with possible contribution from129S2/SvPas, 129/Sv, C57BL/6J, SJL, and/or 129P2/OlaHsd.
C57BL/6-Msh3tm1Rak Trp53tm1Tyj targeted mutation (knockout) Homozygous Msh3tm1Rak, Trp53tm1Tyj mice on a C57BL/6 background with possible contribution from129S2/SvPas, 129/Sv, C57BL/6J, SJL, and/or 129P2/OlaHsd.
C57BL/6-Pou2f1tm1Shrp/+ Trp53tm1Tyj targeted mutation (knockout) &
targeted mutation (other)
Compound mutant mice. The genetic background of these mice was stated to be C57BL/6. It also included at least some 129S2/SvPas and some 129S4/SvJae.
C57BL/6-Qkqk-v Trp53tm1Tyj spontaneous mutation &
targeted mutation (knockout)
Homozygous Qk, Trp53 mice on a C57BL/6 background with possible contribution from DBA/2J and 129S2/SvPas.
C57BL/6-Qkqk-v/+ Trp53tm1Tyj spontaneous mutation &
targeted mutation (knockout)
Heterozygous Qk3, homozygous Trp53 mice on a C57BL/6 background with possible contribution from DBA/2J and 129S2/SvPas.
C57BL/6-Rag1tm1Mom Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53, Rag1 mutant mice on a predominantly C57BL/6 background with possible contribution from 129S2/SvPas, 129S7/SvEvBrd, 129S1/Sv, and/or other strain(s).
C57BL/6-Rbm38tm1.1Xch Trp53tm1Tyj targeted mutation (knockout) Homozygous Rbm38, Trp53 mice on a background that is at least 75% C57BL/6 with contribution from FVB/N from the cre deleter strain use and 129S2/SvPas from the original ES cells. The "EIIa-cre" allele may still be present.
C57BL/6-Sphk1tm1Rlp Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background of these mice was predominantly C57BL/6. These mice were generated by crossing two knockout strains.
C57BL/6-Sphk1tm1Rlp/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was predominantly C57BL/6. These mice were generated by crossing two knockout strains.
C57BL/6-Tg(RIP1-Tag)2Dh Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Compound mutant mice. These mice were generated by crossing strains that had previously been fully backcrossed onto C57BL/6. The genetic background may also include some DBA/2J and/or some 129X1/SvJ and/or some 129S2/SvPas.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. These mice are the product of an intercross between strains on a predominantly C57BL/6 background. The genetic background also contained some 129S2/SvPas and possibly some 129S7/SvEvBrd-Hprt+.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly C57BL/6 and also included some 129S4/SvJae, some 129S2/SvPas and possibly another unspecified strain(s).
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The strains crossed to generate this cohort had been backcrossed to C57BL/6 prior to that cross. The genetic background may also include some 129S2/SvPas, 129P2/OlaHsd, and/or FVB/N.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice on a >95% C57BL/6 background that may also contain contributions from 129S2/SvPas.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly C57BL/6. These mice were generated by crossing two knockout strains.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. These mice were generated by crossing targeted mutant mice on a C57BL/6 genetic background.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice on a C57BL/6 background.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was stated to be C57BL/6. It also included at least some 129S2/SvPas and possibly some 129S4/SvJae.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53 mice on a C57BL/6 background with possible contribution from DBA/2J and 129S2/SvPas.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly C57BL/6, generated by crossing strains each on that backgound. There was likely some contribution from 129S2/SvPas.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53tm1Brd mice on a C57BL/6 background with possible contributions from 129S2/SvPas and an unspecified 129 substrain.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53tm1Tyj mice on a C57BL/6 background with possible contribution from129S2/SvPas, 129/Sv, C57BL/6J, SJL, and/or 129P2/OlaHsd.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53 mutant mice on a predominantly C57BL/6 background with possible contribution of 129S2/SvPas and possibly some other strain(s).
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53 mice on a C57BL/6 background with contribution from 129S2/SvPas from the original ES cells.
C57BL/6-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly C57BL/6 including at least some C57BL/6J. It also included some 129S2/SvPas and possibly some 129X1/SvJ.
C57BL/6-Trp53tm1Tyj Trp63tm1.1Elrf targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was predominantly C57BL/6 and also included some 129S4/SvJae, some 129S2/SvPas and possibly another unspecified strain(s).
C57BL/6-Trp53tm1Tyj Trp63tm1.1Elrf/+ targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was predominantly C57BL/6 and also included some 129S4/SvJae, some 129S2/SvPas and possibly another unspecified strain(s).
C57BL/6J-Espl1Gt(XL058)Byg/+ Trp53tm1Tyj gene trapped &
targeted mutation (knockout)
Heterozygous Espl1Gt(XL058)Byg, homozygous Trp53tm1Tyj mice on a C57BL/6J genetic background with possible contributions from 129P2/OlaHsd and 129S2/SvPas.
C57BL/6J-Fancctm1Mab Trp53tm1Tyj targeted mutation (knockout) Homozygous Fancctm1Mab, Trp53tm1Tyj mice on a C57BL/6J background with possible contributions from 129X1/SvJ, 129S1/Sv, and 129S2/SvPas.
C57BL/6J-Fancctm1Mab/+ Trp53tm1Tyj targeted mutation (knockout) Heterozygous Fancctm1Mab, homozygous Trp53tm1Tyj mice on a C57BL/6J background with possible contributions from 129X1/SvJ, 129S1/Sv, and 129S2/SvPas.
C57BL/6J-Faslgld Trp53tm1Tyj spontaneous mutation &
targeted mutation (knockout)
Double homozygous mice. These mice were generated by crossing two mutant strains (and, subsequently, their progeny) each congenic for a substrain of C57BL/6 (C57BL/6J and C57BL/6JSmn).
C57BL/6J-Kdm6atm1Cdcn Tg(CAG-cre/Esr1*)5Amc Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compound mutant mice. Kdm6a mutants were homozygous (female) and hemizygous (male). The genetic background of these mice was predominantly C57BL/6J. It many have also included some 129S2/SvPas, FVB, CBA, SWR, and/or some other strain(s).
C57BL/6J-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. These mice were generated by crossing two mutant strains (and, subsequently, their progeny) each congenic for a substrain of C57BL/6 (C57BL/6J and C57BL/6JSmn).
C57BL/6J-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was predominantly C57BL/6J. It many have also included some 129S2/SvPas, FVB, and/or some other strain(s).
CE129F2-Trp53tm1Tyj hybrid &
targeted mutation (knockout)
Homozygous mice. These mice were generated by crossing CE129F1-Trp53tm1Tyj/+ heterozygous mice (CE/J background female x 129 background male).
FVB.129S2(B6)-Trp53tm1Tyj/J congenic &
targeted mutation (knockout)
Congenic mice homozygous for a targeted mutation of Trp53 (p53).
FVB.129S2-Trp53tm1Tyj congenic &
targeted mutation (knockout)
Congenic mice homozygous for the Trp53tm1Tyj mutation.
FVB/N-Cdkn2atm2.1Rdp Trp53tm1Tyj targeted mutation (knockout) Homozygous mice on an ~87.5% FVB/N background with contributions from at least 129S2/SvPas and 129S6/SvEvTac
FVB/N-Cdkn2atm2.1Rdp/+ Trp53tm1Tyj targeted mutation (knockout) Heterozygous Cdkn2atm2.1Rdp, homozygous Trp53tm1Tyj mice on an ~87.5% FVB/N background with contributions from at least 129S2/SvPas and 129S6/SvEvTac.
FVB/N-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice on an ~87.5% FVB/N background with contributions from at least 129S2/SvPas and 129S6/SvEvTac
FVB;129S-Tg(C3-1-TAg)cJeg Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice are hemizygous for the transgene and homozygous for the Trp53tm1Tyj allele. The genetic background of these mice is a mixture of FVB/N and 129S (a mixture of 129 substrains including 129S2/SvPas and probably 129S4/SvJae).
FVB;129S-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice is a mixture of FVB/N and 129S (a mixture of 129 substrains including 129S2/SvPas and probably 129S4/SvJae).
STOCK Acdacd Trp53tm1Tyj spontaneous mutation &
targeted mutation (knockout)
Compound mutant mice. This STOCK genetic background is a mixture of C57BL/6J, DW/J, CAST/Ei, and 129S2/SvPas.
STOCK Atmtm1Fwa Terctm1Rdp Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. Terc - G4. This STOCK genetic background was predominantly C57BL/6 and 129/Sv (substrain not specified) and also contained SJL, 129S4/SvJae, and 129S2/SvPas.
STOCK Atmtm1Fwa/+ Terc?/Terc+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice, either heterozygous or wild-type for Terc (G0). This STOCK genetic background was predominantly C57BL/6 and 129/Sv (substrain not specified) and also contained SJL, 129S4/SvJae, and 129S2/SvPas.
STOCK Brca1tm2Arge Trp53tm1Tyj targeted mutation (knockout) Mice homozygous for targeted mutations of Brca1 and Trp53. The genetic background was a mixture of "129/Sv", C57BL/6J, and MF1 (outbred).
STOCK Brca2tm1Brn Ptch1tm1Mps/+ Tg(Nes-cre)1Kln Trp53tm1Tyj targeted mutation (conditional) &
transgenic
Homozygous Brca2tm1Brn & Trp53tm1Tyj, heterozygous Ptch1tm1Mps, and transgenic mice. The genetic background contained contributions from 129P2/OlaHsd, 129X1/SvJ, 129S1/Sv, 129S2/SvPas, C57BL/6, & SJL.
STOCK Brca2tm1Brn Tg(Nes-cre)1Kln Trp53tm1Tyj targeted mutation (conditional) &
transgenic
Mice were homozygous for Brca2tm1Brn and Trp53tm1Tyj and carried the Tg(Nes-cre)1Kln transgene. The genetic background contained contributions from 129P2/OlaHsd, 129S2/SvPas, C57BL/6, and SJL.
STOCK Lig4tm1Pmc Tg(Nes-cre)1Kln Trp53tm1Tyj targeted mutation (conditional) &
transgenic
Mice were homozygous for Lig4tm1Pmc and Trp53tm1Tyj and carried the Tg(Nes-cre)1Kln transgene. The genetic background contained contributions from 129S1/Sv, 129S2/SvPas, C57BL/6, and SJL.
STOCK Lig4tm1Pmc Tg(Nes-cre)1Kln Trp53tm1Tyj Xccr2tm2Pmc targeted mutation (knock-in) &
transgenic
Mice were homozygous for Lig4tm1Pmc, Xccr2tm2Pmc, and Trp53tm1Tyj and carried the Tg(Nes-cre)1Kln transgene. The genetic background contained 129S1/Sv, 129S2/SvPas, C57BL/6, and SJL.
STOCK Nf1tm1Par Tg(GFAP-cre)25Mes Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compound mutant mice. This STOCK genetic background was a mixture of C57BL/6 (~49.5%), 129X1/SvJ ~(49.5%), and FVB (~1%). It also contained some amount of 129S1/Sv and 129S2/SvPas.
STOCK Ptch1tm1Mps/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice homozygous for Trp53tm1Tyj and heterozygous for Ptch1tm1Mps. Background included a mix of C57BL/6, CD1, 129S2/SvPas, 129X1/SvJ, 129S1/Sv, DBA/2J, and possibly others.
STOCK Ptch2tm1Pmc Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. This STOCK genetic background contained BALB/c, C57BL/6, 129S2/SvPas, 129X1/SvJ, and 129S1/Sv.
STOCK Terc?/Terc+ Trp53tm1Tyj targeted mutation (knockout) Mutant mice, either heterozygous or wild-type for Terc (G0). This STOCK genetic background was predominantly C57BL/6 and 129/Sv (substrain not specified) and also contained SJL, 129S2/SvPas, and possibly some 129S4/SvJae.
STOCK Terctm1Rdp Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for both the Terc and Trp53 mutant alleles. This STOCK genetic background is a mixture predominantly of C57BL/6, 129S2/SvPas, and 129/Sv (substrain unspecified), and it also includes some SJL.
STOCK Terctm1Rdp/+ Trp53tm1Tyj targeted mutation (knockout) Mice were heterozygous for the Terc mutant allele and homozygous for the Trp53 mutan allele. This STOCK genetic background is a mixture predominantly of C57BL/6, 129S2/SvPas, and 129/Sv (substrain unspecified), and it also includes some SJL.
STOCK Tg(Ela1-Tgfa)150Bri Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice carried the Tg(Ela1-Tgfa)150Bri transgene & were homozygous for the Trp53tm1Tyj allele. The genetic background of these mice was predominantly a mixture of C57BL/6 and BALB/c with some SJL and/or 129S2/SvPas also possibly involved.
STOCK Tg(GFAP-E2F1)10Fyo Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice were homozygous for the Trp53 allele and carried the transgene. This STOCK genetic background was primarily a mixture of FVB and C57BL/6J with some contribution from 129S2/SvPas.
STOCK Tg(GFAP-E2F1)2Fyo Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice were homozygous for the Trp53 allele and carried the transgene. This STOCK genetic background was primarily a mixture of FVB and C57BL/6J with some contribution from 129S2/SvPas.
STOCK Tg(LPV-TAg121)2Tvd Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice were homozygous for the Trp53 mutant allele and carried the Tg(LPV-TAg121)2Tvd transgene. This STOCK genetic background was a mixture of at least C57BL/6J, DBA/2J, & 129S2/SvPas. It may also contain another 129 substrain, possibly 129S4/SvJae.
STOCK Tg(MMTV-Myc)141-3Led Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was a mixture of mostly FVB and 129 (substrains not specified but contained at least 129S2/SvPas and "129/Sv") and also some CD-1 and C57BL/6J.
STOCK Tg(MtTGFA)42Lmb Cdkn2atm1Rdp Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice were homozygous for the Cdkn2a and Trp53 mutant alleles and carried the Tg(MtTGFA)42Lmb transgene. This STOCK genetic background was a mixture predominantly of C57BL/6 and CD-1 and also included 129/Sv, 129S2/SvPas, and SJL.
STOCK Tg(MtTGFA)42Lmb Cdkn2atm1Rdp/+ Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice were heterozygous for mutant Cdkn2a, homozygous for mutant Trp53, and carried the Tg(MtTGFA)42Lmb transgene. This STOCK genetic background was a mixture predominantly of C57BL/6 and CD-1 and also included 129/Sv, 129S2/SvPas, and SJL.
STOCK Tg(MtTGFA)42Lmb Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice were homozygous for the Trp53 mutant allele and carried the Tg(MtTGFA)42Lmb transgene. This STOCK genetic background was a mixture predominantly of C57BL/6 and CD-1 and also included 129S2/SvPas and possibly some 129/Sv and SJL.
STOCK Tg(Nes-cre)1Kln Trp53tm1Tyj Xccr2tm2Pmc targeted mutation (conditional) &
transgenic
Mice were homozygous for Xccr2tm2Pmc and Trp53tm1Tyj and carried the Tg(Nes-cre)1Kln transgene. The genetic background contained contributions from 129S2/SvPas, C57BL/6, and SJL.
STOCK Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. This STOCK genetic background was a mixture predominantly of C57BL/6 and CD-1 and also included 129S2/SvPas and possibly some 129/Sv and SJL.
STOCK Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. This STOCK genetic background was ~50% C57BL/6 and ~50% BALB/c with some SJL and/or 129S2/SvPas also possibly involved.
STOCK Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. Background included contributions from C57BL/6, 129S2/SvPas, and Mus spretus.
STOCK Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was a mixture of mostly FVB and 129 (substrains not specified but contained at least 129S2/SvPas and "129/Sv") and possibly some CD-1 and C57BL/6J.
STOCK Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. This STOCK genetic background is a mixture of C57BL/6J, DW/J, CAST/Ei, and 129S2/SvPas.
STOCK Trp53tm1Tyj Tg(SFTPC-RAF1-BxB)1Urr targeted mutation (knockout) &
transgenic
Hemizygous transgenic mice, homozygous for the Trp53tm1Tyj allele. Background was said to be ~92.5% C57BL/6 and 7.5% DBA/2, but includes some contribution from 129S2/SvPas as the background of original Trp53 knockout mouse.
STOCK Trp53tm1Tyj Tg(SFTPC-RAF1-BxB)1Urr targeted mutation (knockout) &
transgenic
Hemizygous transgenic mice, homozygous for the Trp53tm1Tyj allele. Background was said to be ~75% '129/Sv' (includes 129S2/SvPas and possibly other substrains) and 25% C57BL/6 x DBA/2.
[not specified]-Brca1tm1Bhk/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was not specified but involved at least some 129P2/OlaHsd and 129S2/SvPas from the ES cells used to generate the mutant alleles.
[not specified]-Brca1tm1Bhk/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was not specified but involved at least some 129P2/OlaHsd and 129S2/SvPas from the ES cells used to generate the mutant alleles.
[not specified]-Cdk4tm1.1Bbd Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Mice were homozgyous for both the Cdk4 and Trp53 mutant alleles. The genetic background of these mice was not specified, but it contained at least some 129X1/SvJ, some 129S1/Sv, some 129S2/SvPas, and some outbred CD-1.
[not specified]-Cdk4tm1.1Bbd/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Mice were heterozygous for the Cdk4 allele and homozygous for the Trp53 allele. The genetic background of these mice was not specified, but it contained at least some 129X1/SvJ, some 129S1/Sv, some 129S4/SvJae, and some outbred CD-1.
[not specified]-Cdk6tm1.1Mama Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Double homozygous mice. The genetic background of these mice was not specified but included 129 (at least 129S2/SvPas), likely some BALB/cJ, and possibly some other strain(s).
[not specified]-Cdk6tm1.1Mama/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Compound mutant mice. The genetic background of these mice was not specified but included 129 (at least 129S2/SvPas), likely some BALB/cJ, and possibly some other strain(s).
[not specified]-Cdkn1btm1Mlf Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice, homozygous knockout for Cdkn1b and Trp53. Background was not specified, but included contributions from 129S2/Sv, 129P2/OlaHsd, 129S4/SvJaeSor, C57BL/6 and possibly other strains.
[not specified]-Cdkn2atm2.1Rdp Trp3tm1Tyj targeted mutation (knockout) Homozygous mice on an unspecified background with possible contributions from 129S6/SvEvTac and 129S2/SvPas.
[not specified]-Cdkn2ctm1Bbd Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice, homozygous knockout for Cdkn2c and Trp53. Background was not specified, but included contributions from 129S2/Sv, 129S1/SvImJ, 129P2/OlaHsd, C57BL/6 and possibly other strains.
[not specified]-Cdkn2ctm1Bbd Trp53tm1Tyj targeted mutation (knockout) These mice were homozygous for both mutant alleles. The genetic background of these mice was not specified but included at least 129S1/Sv and 129S2/SvPas.
[not specified]-Cdkn2ctm1Bbd/+ Trp53tm1Tyj targeted mutation (knockout) These mice were heterozygous for the Cdkn2c allele and homozygous for the Trp53 allele. The genetic background of these mice was not specified but included at least 129S1/Sv and 129S2/SvPas.
[not specified]-Cdkn2dtm1Maro Cdkn1btm1Mlf/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice, homozygous knockout for Cdkn2d and Trp53, and heterozygous knockout for Cdkn1b. Background was not specified, but included contributions from 129S2/Sv, 129P2/OlaHsd, 129S4/SvJaeSor, C57BL/6 and possibly other strains.
[not specified]-Cdkn2dtm1Maro/+ Cdkn2ctm1Bbd Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice, homozygous knockout for Cdkn2c and Trp53, and heterozygous knockout for Cdkn2d. Background was not specified, but included contributions from 129S2/Sv, 129P2/OlaHsd, 129S4/SvJaeSor, C57BL/6 and possibly other strains.
[not specified]-Krastm2Tyj/+ Trp53tm1Tyj targeted mutation (knock-in) &
targeted mutation (knockout)
Kras conditional mutant heterozygous and Trp53 KO homozygous mice. Spontaneous somatic recombination leads to the expression of an activated oncogenic KRAS protein. The genetic background was not specified.
[not specified]-Krastm4Tyj/+ Tg(Pdx1-cre)6Tuv Trp53tm1Tyj targeted mutation (conditional) &
transgenic
Heterozygous Kras, homozygous Trp53 mice carrying the transgene on an unspecified background with contribution from C57BL/6, 129S4/SvJae, 129S2/SvPas, and FVB/N.
[not specified]-Lig4tm1Icrf Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for both Trp53tm1Tyj & Lig4tm1Icrf. The genetic background was not specified, but included contributions from C57BL/6, 129S2/SvPas, other unspecified substrain(s) of 129, and possibly other strains.
[not specified]-Nbntm1Xu Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for the Nbntm1Xu and Trp53tm1Tyj mutations. Background was not specified, but included some contribution from 129S2/SvPas.
[not specified]-Nf2tm1Tyj/+ Trp53tm1Tyj targeted mutation (knockout) Mice are heterozygous for Nf2tm1Tyj and homozygous for Trp53tm1Tyj. The reference did not specify the genetic background, either mixed B6;129S or inbred 129S/Sv.
[not specified]-Ninj1tm1b(KOMP)Wtsi/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background of these mice was not specified but included at least some C57BL/6N and 129S2/SvPas and possibly some FVB/N and/or other strain(s).
[not specified]-Prdm2tm1Shg Trp53tm1Tyj targeted mutation (knockout) Homozygous Prdm2, Trp53 mice on an unspecified background with contributions from C57BL/6, 129/Sv, and possibly 129S2/SvPas.
[not specified]-Prdm2tm1Shg/+ Trp53tm1Tyj targeted mutation (knockout) Heterozygous Prdm2, homozygous Trp53 mice on an unspecified background with contributions from C57BL/6, 129/Sv, and possibly 129S2/SvPas.
[not specified]-Ptch1tm1Mps/+ Trp53tm1Tyj targeted mutation (knockout) These mice were heterozygous for Ptch1tm1Mps and homozygous for Trp53tm1Tyj. The genetic background of these mice was not specified but included C57BL/6, C57BL/6J, 129X1/SvJ, 129S1/Sv, 129S2/SvPas, and DBA/2J.
[not specified]-Ptch1tm1Mps/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice heterozygous for Ptch1tm1Mps and homozygous for Trp53tm1Tyj. Background was not specified, but included contributions from C57BL/6, DBA/2J, 129X1/SvJ, 129S1/Sv, and 129S2/SvPas.
[not specified]-Rb1tm3Tyj Tg(Nes-cre)1Atp Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compound mutant mice. The transgene was inherited paternally. The genetic background of these mice was not specified but included at least C57BL/6 and 129S2/SvPas.
[not specified]-Rb1tm3Tyj Tg(Nes-cre)1Atp Trp53tm1Tyj targeted mutation (conditional) &
targeted mutation (knockout) &
transgenic
Compound mutant mice. The transgene was inherited maternally. The genetic background of these mice was not specified but included at least 129S2/SvPas.
[not specified]-Susd6tm1.1Geno Trp53tm1Tyj targeted mutation (knockout) Double homozygous mice. The genetic background was not specified but included C57BL/6J (at least 50%) and some 129S2/SvPas.
[not specified]-Susd6tm1.1Geno/+ Trp53tm1Tyj targeted mutation (knockout) Compound mutant mice. The genetic background was not specified but included C57BL/6J (at least 50%) and some 129S2/SvPas.
[not specified]-Tg(KRT5-Tert)7664Blas Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Transgenic mice homozygous for the Trp53tm1Tyj allele. The genetic background was not specified but contained contributions from at least C57BL/6, DBA/2, and 129S2/SvPas.
[not specified]-Tg(Lck-Bax)1Knud Tg(Lck-Bax)38Knud Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Homozygous Trp53 KO mice that carried Lck-Bax transgenes from 2 different founders. The genetic background of these mice was not specified but included at least some C57BL/6, C3H/He, and 129S2/SvPas.
[not specified]-Tg(Tyr-HRAS)60Lc Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Mice homozygous for a targeted mutation of Trp53 and transgenic for an activated human HRAS (G12V) oncogene under control of the melanocyte-specific mouse tyrosinase promoter. Genetic background was not specified.
[not specified]-Tg(WAPT121)66Tvd Trp53tm1Tyj targeted mutation (knockout) &
transgenic
Compound mutant mice. The genetic background of these mice was not specified but included at least some C57BL/6J, DBA/2J, and 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was not specified but involved at least some 129S2/SvPas from the ES cells used to generate the mutant allele.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Mice were homozygous for the Trp53tm1Tyj allele. The genetic background of these mice was not specified, but it contained at least some 129S2/SvPas and possibly some 129X1/SvJ, some 129S1/Sv and/or some outbred CD-1.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. Background was not specified but includes contributions from C57BL/6, 129S2/SvPas (and possibly other 129 substrains and DBA/2.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Background was not specified, but included some contribution from 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The full genetic background was not specified but was reported to be predominantly 129S4/SvJae. It also included some 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) These mice were homozygous for the Trp53tm1Tyj allele. The genetic background was not specified but contained contributions from at least C57BL/6, DBA/2, and 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was not specified but included at least 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was not specified but included at least some 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was not specified but included at least some 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice on an unspecified background that had contributions from at least 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous Trp53 mutant mice on an unspecified background with contributions from C57BL/6, 129/Sv, and possibly 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background was not specified but included C57BL/6J (at least 50%) and some 129S2/SvPas.
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was not specified but included 129 (at least 129S2/SvPas), likely some BALB/cJ, and possibly some other strain(s).
[not specified]-Trp53tm1Tyj targeted mutation (knockout) Homozygous mice. The genetic background of these mice was not specified but included at least some 129S2/SvPas and possibly some other strain(s).
[not specified]-Trp53tm1Tyj Tg(SFTPC-RAF1-BxB)1Urr targeted mutation (knockout) &
transgenic
Hemizygous transgenic mice, homozygous for the Trp53tm1Tyj allele. Background was not specified and could be either 75% '129/Sv' 25% C57BL/6 x DBA/2, or 92.5% C57BL/6 and 7.5% DBA/2 plus some residual contribution from 129S2/SvPas.
[not specified]-Trp53tm1Tyj Xrcc4tm1Fwa targeted mutation (knockout) Mice homozygous for targeted mutations of the Trp53 and Xrcc4 genes. The genetic background was not specified.