Strain Tumor Overview (Expanded View)

Strain

C57BL/6-Apctm1Mmt/+ Tg(Vil1-cre/ERT2)23Syr Tgfbr2tm1Hlm

Strain Synonyms

AT  •  C57BL/6-Apctm1Mmt/+ Tg(Vil-cre/ERT2)23Syr Tgfbr2tm1Hlm

Strain Note:

Heterozygous Apc, homozygous Tgfbr2 mutant mice also carrying the transgene on a C57BL/6 background with contribution from 129S2/SvPas, 129S4/SvJae, 129S6/SvEvTac, and DBA/2.

Tumors

4 unique tumor sub-types displayed. A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.
Tumor Name Organ(s) Affected Treatment Type Agents Metastasizes To References Number of Tumor Sub-type Records Frequency Range
Intestine - Small Intestine tumor Intestine - Small Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:261891 1 observed
Intestine adenocarcinoma - mucinous Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:261891 1 66.67
Intestine adenocarcinoma - tubular Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:261891 1 33.33
Intestine adenocarcinoma - well-differentiated Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:261891 1 33.33