Strain Tumor Overview (Expanded View)

Strain

C57BL/6-Apctm2Rak Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy Tg(tetO-Kras*G12D)#Rdp Tg(Vil1-cre/ERT2)23Syr Trp53tm1Brn/+

Strain Synonyms

C57BL/6-Apctm2Rak Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy Tg(tetO-Kras*G12D)#Rdp Tg(Vil-cre/ERT2)23Syr Trp53tm1Brn/+  •  IKA(P/+)

Strain Note:

Compound mutant mice. Mice were backcrossed to C57BL/6 an unknown number of times and had contribution from FVB/N, DBA/2, C57BL/6J, SJL, 129/Sv, 129X1/SvJ, 129S1/Sv, and 129P2/OlaHsd.

Tumors

5 unique tumor sub-types displayed. A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.
Tumor Name Organ(s) Affected Treatment Type Agents Metastasizes To References Number of Tumor Sub-type Records Frequency Range
Intestine - Large Intestine adenoma Intestine - Large Intestine Genetic Modification 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles) doxycycline J:242160 1 64
Intestine - Large Intestine tumor Intestine - Large Intestine Genetic Modification 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles) doxycycline (Unspecified organ) J:242160 2 72.73
Intestine - Small Intestine tumor Intestine - Small Intestine Genetic Modification 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles) doxycycline J:242160 1 0
Intestine adenocarcinoma Intestine Genetic Modification 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles) doxycycline J:242160 1 9
Intestine tumor Intestine Genetic Modification 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles) doxycycline J:242160 2 observed - 72.73