Strain Tumor Overview (Expanded View)

Strain

[not specified]-Apctm1Tno/+ Krastm1Bbd/+ Ptentm2Mak Tg(Vil1-cre/ERT2)23Syr

Strain Synonyms

APK  •  Apcfl/+Ptenfl/flKrasLSL/+  •  VillinCreERT-Apcfl/+Ptenfl/flKrasLSL/+  •  [not specified]-Apctm1Tno/+ Krastm1Bbd/+ Ptentm2Mak Tg(Vil-cre/ERT2)23Syr

Strain Note:

Heterozygous Apc, Kras, homozygous Pten mutant mice also carrying the Tg(Vil-cre/ERT2)23Syr transgene on an unspecified background with possible contributions from 129S4/SvJae, 129X1/SvJ, 129S1/Sv, 129P2/OlaHsd, C57BL/6, and/or DBA/2.

Tumors

6 unique tumor sub-types displayed. A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.
Tumor Name Organ(s) Affected Treatment Type Agents Metastasizes To References Number of Tumor Sub-type Records Frequency Range
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:208067 1 0
Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:208067 1 observed
Intestine - Small Intestine tumor Intestine - Small Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:208067 1 observed
Intestine adenocarcinoma Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:208067 2 observed
Intestine adenoma Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:208067 1 observed
Intestine adenoma - microadenoma Intestine Genetic Modification tamoxifen (For inducing expression from mutant alleles) J:208067 1 observed