Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Expanded View
 
Strain
PL/J
Strain Synonyms L II  •  PL  •  PL(B)  •  PL/Jax  •  Princeton Leukemia
Strain Tumor Overview Collapsed View
Tumors 119 unique tumor sub-types displayed.

A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.

Tumor Name Organ(s) Affected Treatment Type
Agents
Metastasizes
To
References Number of
Tumor Sub-type Records
Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous)
  J:236844 2 0
Adipose tissue lipoma Peritoneal cavity None (spontaneous)
  J:236844 2 0
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous)
  J:236844 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous)
  J:122261
J:236844
3 0 - observed
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous)
  J:236844 2 0
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous)
  J:236844 2 0
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous)
  J:236844 2 0
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous)
  J:122261 1 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous)
  J:236844 2 0
Blood vessel hemangioma Blood vessel None (spontaneous)
  J:236844 2 0 - low
Blood vessel hemangioma Uterus None (spontaneous)
  J:236844 1 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous)
  J:236844 2 0
Blood vessel hemangiosarcoma Liver None (spontaneous)
  J:236844 2 0
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous)
  J:236844 2 0
Bone hyperplasia Bone None (spontaneous)
  J:236844 2 0
Bone lesion - fibro-osseous Bone None (spontaneous)
  J:227044
J:236844
11 0
Epididymis cyst Epididymis None (spontaneous)
  J:236844 1 0
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous)
  J:236844 2 0 - low
Erythrocyte neoplasm Erythrocyte None (spontaneous)
  J:236844 2 0
Esophagus hyperplasia Esophagus None (spontaneous)
  J:236844 2 0
Eye - Harderian gland adenoma Eye - Harderian gland None (spontaneous)
  J:122261 1 observed
Forestomach hyperplasia - papillary Forestomach None (spontaneous)
  J:236844 2 0
Forestomach papilloma Forestomach None (spontaneous)
  J:236844 2 0
Gallbladder cyst Gallbladder None (spontaneous)
  J:236844 2 0
Gallbladder hyperplasia Gallbladder None (spontaneous)
  J:236844 2 0
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous)
  J:236844 2 0
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous)
  J:236844 2 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum None (spontaneous)
  J:122261 1 observed
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous)
  J:236844 2 0
Kidney adenoma Kidney None (spontaneous)
  J:236844 2 0
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell None (spontaneous)
  J:236844 2 0
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 33.33
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous)
  J:236844 2 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous)
  J:236844 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 16.67
Leukocyte leukemia Leukocyte None (spontaneous)
  J:22621
J:55930
3 19 - 90.0
Leukocyte lymphoma Intestine - Small Intestine - Duodenum None (spontaneous)
  J:122261 1 observed
Leukocyte lymphoma Leukocyte None (spontaneous)
  J:236844 2 0 - low
Leukocyte lymphoma - lymphosarcoma Pancreas None (spontaneous)
  J:122261 1 observed
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous)
  J:236844 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous)
  J:236844 2 0
Liver hepatoma Liver None (spontaneous)
  J:236844 2 0
Lung adenoma Lung Chemical/Drug
urethane (ethyl carbamate)
  J:796 1 observed
Lung adenoma Lung None (spontaneous)
  J:175528
J:236844
4 0 - high
Lung carcinoma Lung Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 0
Lung hyperplasia Lung None (spontaneous)
  J:236844 2 0
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
  J:16946 1 67
Lymph node cyst Lymph node None (spontaneous)
  J:236844 2 0
Lymph node hyperplasia Reticulocyte None (spontaneous)
  J:236844 2 0
Mammary gland adenocarcinoma - mixed Mammary gland None (spontaneous)
  J:94093 1 observed
Mammary gland adenocarcinoma - tubular Mammary gland None (spontaneous)
  J:94320 1 observed
Mammary gland tumor Mammary gland None (spontaneous)
  J:55930 1 low
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous)
  J:236844 1 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous)
  J:236844 1 0
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous)
  J:236844 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous)
  J:236844 1 0
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous)
  J:236844 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous)
  J:236844 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous)
  J:236844 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous)
  J:176506 1 0
Myoepithelial cell myoepithelioma Lung None (spontaneous)
  J:236844 2 0
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous)
  J:236844 2 0
Nail squamous cell carcinoma Nail None (spontaneous)
  J:236844 2 0
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous)
  J:236844 1 0
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous)
  J:9301 2 0
Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell None (spontaneous)
  J:236844 1 0
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous)
  J:236844 1 low
Ovary adenoma Ovary None (spontaneous)
  J:236844 1 0
Ovary cyst - bursal Ovary None (spontaneous)
  J:236844 1 0
Ovary hyperplasia - epithelial Ovary None (spontaneous)
  J:236844 1 0
Ovary tumor - tubulostromal Ovary None (spontaneous)
  J:236844 1 0
PNS - Nerve sheath tumor Ear None (spontaneous)
  J:236844 2 0
PNS - Nerve sheath tumor Skin None (spontaneous)
  J:236844 2 0
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous)
  J:236844 2 0
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous)
  J:122261 2 observed
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous)
  J:236844 1 0
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous)
  J:236844 2 0
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous)
  J:236844 2 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous)
  J:236844 2 0
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous)
  J:236844 2 0
Skin hyperplasia - epithelial Ear None (spontaneous)
  J:236844 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous)
  J:236844 2 0
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous)
  J:122261
J:236844
3 0 - observed
Stomach - Glandular cyst Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach - Glandular polyp Stomach - Glandular None (spontaneous)
  J:236844 2 0
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236844 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236844 1 0
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236844 1 0
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous)
  J:236844 2 0
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous)
  J:236844 2 0
Ureter hyperplasia Muscle - Smooth None (spontaneous)
  J:236844 2 0
Ureter polyp Ureter None (spontaneous)
  J:236844 2 0
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous)
  J:236844 2 0
Urinary bladder papilloma Urinary bladder None (spontaneous)
  J:236844 2 0
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous)
  J:236844 1 moderate
Uterus adenoma Uterus None (spontaneous)
  J:236844 1 0
Uterus fibropapilloma Uterus None (spontaneous)
  J:236844 1 0
Vagina papilloma Vagina None (spontaneous)
  J:236844 1 0
Vulva squamous cell carcinoma Vulva None (spontaneous)
  J:236844 1 0
(Unspecified organ) tumor (Unspecified organ) None (spontaneous)
  J:22621 2 19 - 71
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=14
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/PL.shtml
JAX Mice http://jaxmice.jax.org/strain/000680.html