Mouse Tumor Biology Database (MTB)
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Last Database Update
2020-01-26
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Expanded View
 
Strain
VM.129-Trp53tm1Brd
Strain Synonyms p53-deficient  •  p53 null (-/-)  •  VM (-/-)  •  VM.129(B6)-Trp53tm1Brd  •  VM congenic p53 null (-/-)
Strain Note: Homozygotes. This mutation had been backcrossed onto VM. The mutant allele was originally generated in "129/Sv" and had been crossed to C57BL/6 prior to the backcrossing.
Strain Tumor Overview Collapsed View
Tumors 11 unique tumor sub-types displayed.

A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.

Tumor Name Organ(s) Affected Treatment Type
Agents
Metastasizes
To
References Number of
Tumor Sub-type Records
Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous)
Lymph node
Retroperitoneum
J:51144 3 18
Bone osteosarcoma Bone None (spontaneous)
  J:51144 1 4.55
CNS - Brain - Astrocyte astrocytoma - anaplastic CNS - Brain - Astrocyte None (spontaneous)
  J:51144 1 0
CNS - Meninges meningioma CNS - Meninges None (spontaneous)
  J:51144 1 4.55
Germ cell (sex not specified) teratoma Germ cell (sex not specified) None (spontaneous)
  J:51144 1 4.55
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon None (spontaneous)
  J:51144 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous)
  J:51144 1 0
Leukocyte lymphoma - non-Hodgkin Leukocyte None (spontaneous)
  J:51144 1 77
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous)
  J:51144 1 0
Prostate gland tumor Prostate gland None (spontaneous)
  J:51144 1 0
(Unspecified organ) tumor - undifferentiated (Unspecified organ) None (spontaneous)
  J:51144 1 0