Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-10
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Expanded View
 
Strain
BALB/c
Strain Synonyms Bagg  •  Bagg albino  •  Bagg Albino  •  BALB  •  balb/c  •  B alb C  •  BALB/C  •  BALB/c (WT)  •  C  •  Cb  •  C strain  •  WT
Strain Note: Substrain not specified.
Strain Tumor Overview Collapsed View
Tumors 114 unique tumor sub-types displayed.

A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.

Tumor Name Organ(s) Affected Treatment Type
Agents
Metastasizes
To
References Number of
Tumor Sub-type Records
Frequency Range
Adrenal gland - Cortex tumor Adrenal gland - Cortex None (spontaneous)
  J:24830 1 observed
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Cortex None (spontaneous)
  J:44011 2 93 - 100
Blood vessel hemangioendothelioma Blood vessel Chemical/Drug
4-o-tolylazo-o-toluidine (2-amino-5-azotoluene)
  J:24688 1 observed
Blood vessel hemangioendothelioma Blood vessel Chemical/Drug
o-aminoazotoluene
  J:23470
J:97121
2 high
Blood vessel hemangiosarcoma Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:47856 4 3.6 - 35
Blood vessel tumor - benign Spleen Virus
R7 - MoMuSV 124 variant
MoMuLV-TB - Moloney murine leukemia virus, TB strain
  J:47992 1 70
Bone osteosarcoma - fibroblastic Bone None (spontaneous)
Lung J:41414 2 observed
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 2 7.7 - 17
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast Virus
R7 - MoMuSV 124 variant
MoMuLV-TB - Moloney murine leukemia virus, TB strain
  J:47992 1 100
Connective tissue - Fibroblast tumor Lung Virus
MoMuLV-TB - Moloney murine leukemia virus, TB strain
R7 - MoMuSV 124 variant
  J:47992 1 81
Connective tissue - Fibroblast tumor Liver Virus
R7 - MoMuSV 124 variant
MoMuLV-TB - Moloney murine leukemia virus, TB strain
  J:47992 1 observed
Connective tissue - Synovium synovioma Connective tissue - Synovium None (spontaneous)
  J:97121 1 2.0 - 8.0
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
cigarette smoke
  J:84490 1 25
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
  J:84490 1 0
Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon None (spontaneous)
  J:84490 1 0
Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon Chemical/Drug
cigarette smoke
  J:84490 2 0
Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
  J:84490 2 0 - 9.1
Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
cigarette smoke
  J:84490 2 42 - 80
Intestine - Large Intestine - Colon polyp - adenomatous Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
  J:84490 1 9.1
Intestine - Large Intestine - Colon polyp - adenomatous Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
cigarette smoke
  J:84490 2 58 - 80
Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine None (spontaneous)
  J:35020 1 0
Intestine metaplasia Intestine Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:47856 1 0
Kidney adenocarcinoma Kidney None (spontaneous)
  J:24830 1 40
Kidney tumor Kidney None (spontaneous)
  J:97121 1 25.0 - 48.0
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell plasmacytoma Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell Chemical/Drug
mineral oil
  J:50296
J:97121
2 observed
Leukocyte - Lymphocyte - Pre-B-lymphocyte hyperplasia Leukocyte - Lymphocyte - Pre-B-lymphocyte None (spontaneous)
  J:80332 1 0
Leukocyte - Lymphocyte - Pre-B-lymphocyte tumor Leukocyte - Lymphocyte - Pre-B-lymphocyte None (spontaneous)
  J:80332 1 0.05
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte Virus
MoMuLV-TB - Moloney murine leukemia virus, TB strain
  J:47992 1 observed
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous)
  J:97121 1 0
Leukocyte - Lymphocyte lymphoma - small lymphocytic Leukocyte - Lymphocyte None (spontaneous)
  J:97121 1 5
Leukocyte leukemia Leukocyte None (spontaneous)
  J:23487
J:54944
J:97121
5 0 - 14
Leukocyte leukemia Leukocyte Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 2 35 - 52
Leukocyte leukemia Leukocyte Chemical/Drug
dimethylbenzanthracene (DMBA)
  J:97121 1 observed
Leukocyte leukemia Leukocyte Virus
Friend leukemia virus (FLV)
  J:97121 1 observed
Leukocyte lymphoma Leukocyte Virus
A-MuLV - Abelson murine leukemia virus (A-MuLV-P160)
  J:24306 3 95 - 100
Leukocyte lymphoma Leukocyte Virus
MoMuLV - Moloney murine leukemia virus (M-MuLV) (MMLV)
  J:24306 2 0 - 93
Liver hepatoma Liver None (spontaneous)
  J:23487 2 0
Liver hepatoma Liver Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 2 0 - 12
Liver hepatoma - malignant Liver Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 2 0
Lung - Alveolus tumor Lung - Alveolus None (spontaneous)
  J:24830 1 high
Lung adenoma Lung None (spontaneous)
  J:145754
J:23487
3 1.7 - 10
Lung adenoma Lung Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 2 92 - 100
Lung adenoma Lung Chemical/Drug
mainstream cigarette smoke (MCS)
  J:145754 1 21.05
Lung carcinoma Lung Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 2 8.7 - 27
Lung carcinoma Lung Chemical/Drug
mainstream cigarette smoke (MCS)
  J:145754 1 0
Lung carcinoma Lung None (spontaneous)
  J:145754 1 0
Lung hyperplasia Lung None (spontaneous)
  J:145754 1 observed
Lung hyperplasia Lung Chemical/Drug
mainstream cigarette smoke (MCS)
  J:145754 1 observed
Lung papilloma Lung None (spontaneous)
  J:145754 1 0
Lung papilloma Lung Chemical/Drug
mainstream cigarette smoke (MCS)
  J:145754 1 0
Lung tumor Lung None (spontaneous)
  J:145754
J:23463
J:23470
J:235854
J:24310
J:24654
J:50296
J:97121
16 observed - 45
Lung tumor Lung Chemical/Drug
methylcholanthrene (MCA)
  J:97121 1 high
Lung tumor Lung Chemical/Drug
hydrazine sulfate
  J:22757
J:23463
2 high - 100
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
  J:23463 3 53 - 85
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
thymectomy
  J:23463 1 very high
Lung tumor Lung Other
splenectomy
urethane (ethyl carbamate)
  J:23463 1 very high
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
cortisone
  J:23463 1 very high
Lung tumor Lung Chemical/Drug
isoniazid
  J:23463 1 100
Lung tumor Lung Chemical/Drug
isonicotinic acid
  J:23463 1 19
Lung tumor Lung Chemical/Drug
iproniazid
  J:23463 1 35
Lung tumor Lung Chemical/Drug
phenylhydrazine
  J:23463 1 53
Lung tumor Lung Chemical/Drug
benzoylhydrazine
  J:23463 1 90
Lung tumor Lung Chemical/Drug
2-methoxybenzoylhydrazine
  J:23463 1 95
Lung tumor Lung Chemical/Drug
4-methoxybenzoylhydrazine
  J:23463 1 95
Lung tumor Lung Chemical/Drug
mainstream cigarette smoke (MCS)
  J:145754 2 observed - 21.05
Mammary gland adenoacanthoma Mammary gland None (spontaneous)
  J:7178 1 2.9
Mammary gland adenocarcinoma Mammary gland None (spontaneous)
Liver J:94314
J:97121
5 0 - 5
Mammary gland carcinoma Mammary gland Diet
corn oil
7,12-dimethylbenz[a]anthracene (DMBA)
  J:15439 1 77
Mammary gland carcinoma Mammary gland Diet
menhaden oil
7,12-dimethylbenz[a]anthracene (DMBA)
corn oil
  J:15439 1 36
Mammary gland carcinoma Mammary gland Diet
coconut oil
7,12-dimethylbenz[a]anthracene (DMBA)
corn oil
  J:15439 1 45
Mammary gland carcinoma Mammary gland None (spontaneous)
  J:24308 1 10
Mammary gland carcinoma Mammary gland Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 1 0
Mammary gland normal tissue (control) Mammary gland None (spontaneous)
  J:216041 1 not applicable
Mammary gland tumor Mammary gland None (spontaneous)
  J:166288
J:23470
J:24654
J:41162
J:50296
J:54944
J:55930
J:7071
J:97121
14 0 - 30
Mammary gland tumor Mammary gland Hormone
pituitary isograft
  J:46444 1 0
Mammary gland tumor Mammary gland Virus
NIV - nodule-inducing virus
  J:46444 1 0
Mammary gland tumor Mammary gland Chemical/Drug
methylcholanthrene (MCA)
  J:54944 1 8
Mammary gland tumor Mammary gland Virus
MMTV - mouse mammary tumor virus
  J:166288
J:23470
J:54944
3 8 - high
Muscle - Striated - Skeletal - Diaphragm tumor Muscle - Striated - Skeletal - Diaphragm Virus
R7 - MoMuSV 124 variant
MoMuLV-TB - Moloney murine leukemia virus, TB strain
  J:47992 1 observed
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 1 3.8
Myoepithelial cell myoepithelioma Salivary gland - Parotid None (spontaneous)
  J:24830
J:27148
2 observed - 4
Myoepithelial cell myoepithelioma Myoepithelial cell None (spontaneous)
  J:22767
J:23470
2 observed
Ovary carcinoma Ovary Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 1 0
Renal pelvis carcinoma Renal pelvis Chemical/Drug
N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)
  J:47713 1 12.5
Reticular cell reticulum cell neoplasm Reticular cell None (spontaneous)
  J:97121 2 3 - 23
Salivary gland carcinoma Salivary gland Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 1 3.8
Skin carcinoma Skin Chemical/Drug
12-O-tetradecanoylphorbol-13-acetate (TPA)
7,12-dimethylbenz[a]anthracene (DMBA)
  J:91957 1 observed
Skin papilloma Skin Chemical/Drug
7,12-dimethylbenz[a]anthracene (DMBA)
12-O-tetradecanoylphorbol-13-acetate (TPA)
  J:91957 1 observed
Skin tumor Skin Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:97121 1 observed
Stomach - Glandular adenocarcinoma Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
Lymph node J:40723
J:45381
J:47856
8 0 - 77
Stomach - Glandular adenocarcinoma Stomach - Glandular Chemical/Drug
catechol
  J:45381 2 0
Stomach - Glandular adenocarcinoma Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
catechol
  J:45381 6 0 - 70
Stomach - Glandular adenocarcinoma Stomach - Glandular None (spontaneous)
  J:45381 1 0
Stomach - Glandular adenoma Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:47856 4 53 - 64
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:40723 1 observed
Stomach - Glandular papilloma Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:40723 1 observed
Stomach - Glandular squamous cell carcinoma Stomach - Glandular Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:40723 1 observed
Stomach adenoma Stomach Chemical/Drug
N-methyl-N-nitrosourea (MNU)
  J:45381 2 0
Stomach adenoma Stomach Chemical/Drug
catechol
  J:45381 4 0 - 33
Stomach adenoma Stomach Chemical/Drug
N-methyl-N-nitrosourea (MNU)
catechol
  J:45381 6 10 - 37
Stomach adenoma Stomach None (spontaneous)
  J:45381 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:24830 1 observed
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:24830 1 observed
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) Hormone
estrogen
  J:24830 1 observed
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) Hormone
diethylstilbestrol (DES)
  J:23470
J:97121
2 high
Thymus thymoma Thymus Virus
A-MuLV - Abelson murine leukemia virus (A-MuLV-P160)
  J:24306 1 10
Ureter carcinoma Ureter Chemical/Drug
N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)
  J:47713 1 0
Urinary bladder carcinoma Urinary bladder Chemical/Drug
N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)
  J:47713 1 100
Uterus adenocarcinoma Uterus None (spontaneous)
  J:24830 1 observed
Uterus tumor Uterus Chemical/Drug
dimethylbenzanthracene (DMBA)
  J:97121 1 observed
(Unspecified organ) angioendothelioma CNS - Brain Virus
MoMuLV-TB - Moloney murine leukemia virus, TB strain
R7 - MoMuSV 124 variant
  J:47992 1 60
(Unspecified organ) angioma (Unspecified organ) None (spontaneous)
  J:97121 1 6
(Unspecified organ) reticuloendothelial neoplasm (Unspecified organ) None (spontaneous)
  J:97121 1 11.0 - 20.0
(Unspecified organ) squamous cell carcinoma (Unspecified organ) Chemical/Drug
9,10-dimethyl-1,2-benzanthracene (DMBA)
  J:23487 1 8.7
Other Database Links
Additional information about these mice:
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/BALB.shtml