Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-10
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Expanded View
 
Strain
C57BL/6J
Strain Synonyms B6  •  B/6  •  B6J  •  B6 WT  •  Bl/6  •  Black 6  •  C57  •  C57/B16  •  C57/Bl  •  C57BL  •  C57/Bl6  •  C57BL/6  •  C57BL/6 from Jackson Laboratory  •  C57/Bl 6J  •  C57Bl/6J  •  C57BL6/J  •  C57BL/6J (F129+51)  •  C57BL/6J, H-2b  •  C57BL/6J inbred WT  •  C57BL/6J+/+  •  C57BL/6J (UW)  •  C57BL/6J wild-type  •  C57 Black  •  C57 black subline 6  •  control  •  Ctr  •  p53+/+  •  p53 wild-type (+/+)  •  p21+/+p27+/+  •  wild type  •  wild-type  •  wild-type C57BL/6J  •  wild-type (WT)  •  WT  •  WT-Control  •  WT-CR
Strain Tumor Overview Collapsed View
Tumors 541 unique tumor sub-types displayed.

A tumor sub-type is a set of tumors that share the same tumor name, organ affected, treatment agent, and metastatic status/localization.

Tumor Name Organ(s) Affected Treatment Type
Agents
Metastasizes
To
References Number of
Tumor Sub-type Records
Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous)
  J:236844 2 0
Adipose tissue lipoma Scrotum None (spontaneous)
  J:122261 1 observed
Adipose tissue lipoma Peritoneal cavity None (spontaneous)
  J:236844 2 0
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous)
  J:236844 2 0 - very low
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous)
  J:122261
J:236844
3 0 - observed
Adrenal gland - Cortex normal tissue (control) Adrenal gland - Cortex None (spontaneous)
  J:94320 1 not applicable
Adrenal gland - Medulla normal tissue (control) Adrenal gland - Medulla None (spontaneous)
  J:94320 3 not applicable
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous)
  J:236844 2 0
Adrenal gland - Medulla pheochromocytoma - malignant Adrenal gland - Medulla None (spontaneous)
  J:236843 1 1
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell None (spontaneous)
  J:256619
J:94320
3 0 - observed
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell Diet
calorie restricted
  J:256619 4 0 - 2.0
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous)
  J:236844 2 0 - moderate
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous)
  J:236844 2 0
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous)
  J:122261 4 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous)
  J:236844 2 0
Blood vessel - Aorta metaplasia - cartilaginous Blood vessel - Aorta None (spontaneous)
  J:88112 1 0
Blood vessel hemangioma Liver None (spontaneous)
  J:232380 2 2 - 6
Blood vessel hemangioma Blood vessel None (spontaneous)
  J:236844 2 0
Blood vessel hemangioma Spleen None (spontaneous)
  J:236843 1 1
Blood vessel hemangioma Uterus None (spontaneous)
  J:236844 1 0
Blood vessel hemangioma - capillary Blood vessel None (spontaneous)
  J:30363 1 observed
Blood vessel hemangioma - capillary Liver None (spontaneous)
  J:30363 1 observed
Blood vessel hemangioma - cavernous Ovary None (spontaneous)
  J:122261 1 observed
Blood vessel hemangioma - cavernous Spleen None (spontaneous)
  J:122261 1 observed
Blood vessel hemangiosarcoma Spleen None (spontaneous)
  J:143281
J:236843
J:256619
4 0 - 4.0
Blood vessel hemangiosarcoma Liver None (spontaneous)
  J:122261
J:143281
J:232380
J:236843
J:236844
J:256619
9 0 - 2
Blood vessel hemangiosarcoma Spleen Diet
calorie restricted
  J:143281
J:256619
5 0
Blood vessel hemangiosarcoma Liver Diet
calorie restricted
  J:143281
J:256619
5 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous)
  J:223430
J:236843
J:236844
5 0 - 4
Blood vessel hemangiosarcoma Blood vessel Radiation
Cesium-137
  J:223430 2 0
Blood vessel hemangiosarcoma Uterus None (spontaneous)
  J:236843 1 observed
Blood vessel hemangiosarcoma Ovary None (spontaneous)
  J:236843 1 observed
Blood vessel hemangiosarcoma Skin None (spontaneous)
  J:236843 1 observed
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous)
  J:236844 2 0
Blood vessel neoplasm Blood vessel None (spontaneous)
  J:235854 4 2 - 4
Blood vessel normal tissue (control) Blood vessel None (spontaneous)
  J:94320 2 not applicable
Blood vessel tumor (Unspecified organ) Diet
(see notes regarding diet)
  J:145013 1 observed
Bone - Vertebral column - Vertebra osteosarcoma Bone - Vertebral column - Vertebra None (spontaneous)
  J:236843 1 1
Bone - Vertebral column - Vertebra osteosarcoma - chondroblastic Bone - Vertebral column - Vertebra None (spontaneous)
  J:94320 1 observed
Bone hyperplasia Bone None (spontaneous)
  J:236844 2 0
Bone lesion - fibro-osseous Bone None (spontaneous)
  J:227044
J:236844
11 0 - 13.33
Bone marrow normal tissue (control) Bone marrow None (spontaneous)
  J:94320 1 not applicable
Bone neoplasm Bone None (spontaneous)
  J:235854 2 0 - 2
Bone osteosarcoma Bone None (spontaneous)
  J:94310
J:94314
2 observed
CNS - Brain - Choroid plexus normal tissue (control) CNS - Brain - Choroid plexus None (spontaneous)
  J:94313
J:94320
2 not applicable
CNS - Brain - Ependyma normal tissue (control) CNS - Brain - Ependyma None (spontaneous)
  J:94320 1 not applicable
CNS - Brain - Glial cell normal tissue (control) CNS - Brain - Glial cell None (spontaneous)
  J:94313 1 not applicable
CNS - Brain - Neuron normal tissue (control) CNS - Brain - Neuron None (spontaneous)
  J:94320 1 not applicable
CNS - Brain glioma CNS - Brain None (spontaneous)
  J:142242 1 0
CNS - Brain normal tissue (control) CNS - Brain None (spontaneous)
  J:94313
J:94320
2 not applicable
CNS - Spinal cord normal tissue (control) CNS - Spinal cord None (spontaneous)
  J:94320 1 not applicable
Connective tissue - Cartilage - Articular hyperplasia Limb - Hindlimb None (spontaneous)
  J:88112 1 0
Connective tissue - Cartilage hyperplasia Bone - Sternum None (spontaneous)
  J:88112 1 0
Connective tissue - Cartilage hyperplasia Ear - Outer ear None (spontaneous)
  J:88112 1 0
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast None (spontaneous)
  J:236843 1 4
Connective tissue - Fibroblast fibrosarcoma Uterus None (spontaneous)
  J:236843 1 observed
Connective tissue - Fibroblast fibrosarcoma Skin None (spontaneous)
  J:236843 1 observed
Connective tissue - Fibroblast fibrosarcoma Perirenal tissue None (spontaneous)
  J:236843 1 observed
Connective tissue - Fibroblast fibrosarcoma Ear None (spontaneous)
  J:236843 1 observed
Dendritic cell normal tissue (control) Lymph node None (spontaneous)
  J:94320 1 not applicable
Epididymis cyst Epididymis None (spontaneous)
  J:236844 1 0
Epididymis normal tissue (control) Epididymis None (spontaneous)
  J:94320 1 not applicable
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous)
  J:143281
J:236844
3 0
Erythrocyte leukemia - erythroleukemia Liver None (spontaneous)
  J:143281 1 0
Erythrocyte leukemia - erythroleukemia Spleen Diet
calorie restricted
  J:143281 1 3.3
Erythrocyte leukemia - erythroleukemia Liver Diet
calorie restricted
  J:143281 1 3.3
Erythrocyte neoplasm Erythrocyte None (spontaneous)
  J:236844 2 0
Esophagus hyperplasia Esophagus None (spontaneous)
  J:236844
J:81055
3 0
Esophagus hyperplasia Esophagus Diet
zinc-deficient
  J:81055 1 observed
Esophagus normal tissue (control) Esophagus None (spontaneous)
  J:94310
J:94320
3 not applicable
Esophagus squamous cell carcinoma Esophagus Chemical/Drug
N-amyl-N-methylnitrosoamine (AMN)
  J:48901 1 observed
Esophagus tumor Esophagus None (spontaneous)
  J:48901 1 0
Esophagus tumor Esophagus Chemical/Drug
N-amyl-N-methylnitrosoamine (AMN)
  J:48901 1 100
Esophagus tumor Esophagus Chemical/Drug
N-nitrosomethylbenzylamine (NMBA)
zinc-deficient
  J:81055 1 0
Esophagus tumor Esophagus Chemical/Drug
N-nitrosomethylbenzylamine (NMBA)
  J:81055 1 0
Eye - Conjunctiva normal tissue (control) Eye - Conjunctiva None (spontaneous)
  J:94320 1 not applicable
Eye - Cornea normal tissue (control) Eye - Cornea None (spontaneous)
  J:94313
J:94320
3 not applicable
Eye - Eyelid normal tissue (control) Eye - Eyelid None (spontaneous)
  J:94313 1 not applicable
Eye - Harderian gland adenoma Eye - Harderian gland None (spontaneous)
  J:122261 1 observed
Eye - Harderian gland neoplasm Eye - Harderian gland None (spontaneous)
  J:235854 4 0
Eye - Retina normal tissue (control) Eye - Retina None (spontaneous)
  J:94320 1 not applicable
Eye normal tissue (control) Eye None (spontaneous)
  J:94310 1 not applicable
Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach Diet
zinc-deficient
N-nitrosomethylbenzylamine (NMBA)
  J:81055 1 13
Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach Chemical/Drug
N-nitrosomethylbenzylamine (NMBA)
  J:81055 1 0
Forestomach hyperplasia Forestomach Diet
zinc-deficient
  J:81055 1 observed
Forestomach hyperplasia Forestomach None (spontaneous)
  J:81055 1 0
Forestomach hyperplasia - papillary Forestomach None (spontaneous)
  J:236844 2 0
Forestomach normal tissue (control) Forestomach None (spontaneous)
  J:94320 1 not applicable
Forestomach papilloma Forestomach None (spontaneous)
  J:236844 2 very low
Forestomach tumor Forestomach Diet
zinc-deficient
N-nitrosomethylbenzylamine (NMBA)
  J:81055 1 13
Forestomach tumor Forestomach Chemical/Drug
N-nitrosomethylbenzylamine (NMBA)
  J:81055 1 0
Gallbladder cyst Gallbladder None (spontaneous)
  J:236844 2 0
Gallbladder hyperplasia Gallbladder None (spontaneous)
  J:236844 2 0
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous)
  J:236844 2 0
Gastrointestinal tract tumor Gastrointestinal tract None (spontaneous)
  J:38850 1 0
Gingiva squamous cell carcinoma - well differentiated Gingiva None (spontaneous)
  J:122261 1 observed
Heart normal tissue (control) Heart None (spontaneous)
  J:94310
J:94320
2 not applicable
Intestine - Large Intestine - Cecum adenoma - flat Intestine - Large Intestine - Cecum Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum Chemical/Drug
dextran sulfate sodium (DSS)
  J:46553 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous)
  J:236844 2 0
Intestine - Large Intestine - Colon - Distal adenocarcinoma Intestine - Large Intestine - Colon - Distal None (spontaneous)
  J:38850 1 0
Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal None (spontaneous)
  J:38850 1 0
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal Chemical/Drug
azoxymethane (AOM)
  J:80268 1 observed
Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal Chemical/Drug
azoxymethane (AOM)
  J:80268 1 0
Intestine - Large Intestine - Colon - Medial adenocarcinoma Intestine - Large Intestine - Colon - Medial None (spontaneous)
  J:38850 1 0
Intestine - Large Intestine - Colon - Medial adenoma Intestine - Large Intestine - Colon - Medial None (spontaneous)
  J:38850 1 0
Intestine - Large Intestine - Colon - Proximal adenocarcinoma Intestine - Large Intestine - Colon - Proximal None (spontaneous)
  J:38850 1 0
Intestine - Large Intestine - Colon - Proximal adenoma Intestine - Large Intestine - Colon - Proximal None (spontaneous)
  J:38850 1 0
Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal Chemical/Drug
azoxymethane (AOM)
  J:80268 1 0
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous)
  J:236844 2 0
Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon Chemical/Drug
dextran sulfate sodium (DSS)
  J:46553 2 observed
Intestine - Large Intestine - Colon normal tissue (control) Intestine - Large Intestine - Colon None (spontaneous)
  J:94310
J:94320
3 not applicable
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug
1,2-dimethylhydrazine (DMH)
  J:28367 1 observed
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug
azoxymethane (AOM)
  J:56012
J:60015
2 observed
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug
troglitazone
  J:49813 1 0
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug
azoxymethane (AOM)
dextran sulfate sodium (DSS)
  J:242437 1 100
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
AIN-76A
  J:145013 3 0 - 6.67
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
New western diet (NWD) TD.96096
  J:145013 3 0 - 26.67
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
New western diet (NWD) TD.96096
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
Calcium-enriched
  J:145013 2 0 - 4.55
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
New western diet (NWD) TD.96096
Folic acid-enriched
  J:145013 3 0 - 27.78
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
New western diet (NWD) TD.96096
choline-enriched
  J:145013 1 10
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
New western diet (NWD) TD.96096
methionine-enriched
  J:145013 3 11.11 - 18.75
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
high fiber
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
choline-enriched
New western diet (NWD) TD.96096
  J:145013 2 5.56 - 8.7
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 2 0 - 29.41
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Diet
Calcium-enriched
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine None (spontaneous)
  J:35020 1 0
Intestine - Large Intestine tumor Intestine - Large Intestine Chemical/Drug
dextran sulfate sodium (DSS)
azoxymethane (AOM)
  J:242437 1 100
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous)
  J:122261
J:236844
3 0 - observed
Intestine - Small Intestine - Duodenum adenocarcinoma Intestine - Small Intestine - Duodenum None (spontaneous)
  J:38850 1 0
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844
J:38850
3 0
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Duodenum lesion Intestine - Small Intestine - Duodenum Chemical/Drug
N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)
  J:64399 2 observed
Intestine - Small Intestine - Duodenum normal tissue (control) Intestine - Small Intestine - Duodenum None (spontaneous)
  J:94320 3 not applicable
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Ileum adenocarcinoma Intestine - Small Intestine - Ileum None (spontaneous)
  J:38850 1 0
Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum None (spontaneous)
  J:38850 1 0
Intestine - Small Intestine - Ileum normal tissue (control) Intestine - Small Intestine - Ileum None (spontaneous)
  J:86113 1 not applicable
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Jejunum adenocarcinoma Intestine - Small Intestine - Jejunum None (spontaneous)
  J:38850 1 0
Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum None (spontaneous)
  J:38850 1 0
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous)
  J:236844 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous)
  J:236844
J:94307
3 0 - observed
Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine - Small Intestine adenoma - tubular Intestine - Small Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine - Small Intestine normal tissue (control) Intestine - Small Intestine None (spontaneous)
  J:94310
J:94313
J:94320
4 not applicable
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous)
  J:87459 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine Chemical/Drug
2-(acetyloxy)benzoic acid 4-(nitrooxy methyl)phenyl ester) (NO-ASA)
  J:87459 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
AIN-76A
  J:145013 3 0 - 26.67
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
New western diet (NWD) TD.96096
  J:145013 3 0 - 26.67
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
Calcium-enriched
New western diet (NWD) TD.96096
  J:145013 1 15.38
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
New western diet (NWD) TD.96096
Folic acid-enriched
  J:145013 2 7.14 - 22.22
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
choline-enriched
New western diet (NWD) TD.96096
  J:145013 2 10 - 13.04
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
methionine-enriched
New western diet (NWD) TD.96096
  J:145013 1 16.67
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 2 0 - 6.25
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
Calcium-enriched
New western diet (NWD) TD.96096
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 9.09
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
Folic acid-enriched
New western diet (NWD) TD.96096
  J:145013 1 26.09
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
New western diet (NWD) TD.96096
methionine-enriched
  J:145013 2 11.11 - 25
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
New western diet (NWD) TD.96096
Calcium-enriched
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 5.56
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
New western diet (NWD) TD.96096
choline-enriched
  J:145013 1 33.33
Intestine - Small Intestine tumor Intestine - Small Intestine Diet
high fiber
New western diet (NWD) TD.96096
  J:145013 1 11.76
Intestine adenocarcinoma Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine adenoma Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine adenoma Intestine Diet
AIN-76A
  J:145013 1 observed
Intestine adenoma Intestine Diet
New western diet (NWD) TD.96096
  J:145013 1 observed
Intestine adenoma Intestine Diet
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
Calcium-enriched
New western diet (NWD) TD.96096
  J:145013 1 observed
Intestine adenoma Intestine Diet
Folic acid-enriched
New western diet (NWD) TD.96096
  J:145013 1 observed
Intestine adenoma Intestine Diet
choline-enriched
New western diet (NWD) TD.96096
  J:145013 1 observed
Intestine adenoma Intestine Diet
New western diet (NWD) TD.96096
methionine-enriched
  J:145013 1 observed
Intestine adenoma Intestine Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 1 observed
Intestine adenoma - tubular Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine carcinoma Intestine Diet
AIN-76A
  J:145013 1 observed
Intestine carcinoma Intestine Diet
New western diet (NWD) TD.96096
  J:145013 1 observed
Intestine carcinoma Intestine Diet
Calcium-enriched
New western diet (NWD) TD.96096
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 observed
Intestine carcinoma Intestine Diet
New western diet (NWD) TD.96096
Folic acid-enriched
  J:145013 1 observed
Intestine carcinoma Intestine Diet
New western diet (NWD) TD.96096
choline-enriched
  J:145013 1 observed
Intestine carcinoma Intestine Diet
methionine-enriched
New western diet (NWD) TD.96096
  J:145013 1 observed
Intestine carcinoma Intestine Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 1 observed
Intestine carcinoma - invasive Intestine Diet
(see notes regarding diet)
  J:145013 2 observed
Intestine carcinoma - invasive Intestine Diet
AIN-76A
  J:145013 1 0
Intestine carcinoma - invasive Intestine Diet
New western diet (NWD) TD.96096
methionine-enriched
  J:145013 1 observed
Intestine carcinoma - invasive Intestine Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 1 2
Intestine carcinoma - invasive Intestine Diet
New western diet (NWD) TD.96096
Calcium-enriched
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 0
Intestine carcinoma - invasive Intestine Diet
Folic acid-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine carcinoma - invasive Intestine Diet
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine carcinoma - invasive Intestine Diet
New western diet (NWD) TD.96096
choline-enriched
  J:145013 1 0
Intestine lesion Intestine Diet
AIN-76A
  J:145013 1 0
Intestine lesion Intestine Diet
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine lesion Intestine Diet
Calcium-enriched
New western diet (NWD) TD.96096
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 0
Intestine lesion Intestine Diet
Folic acid-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine lesion Intestine Diet
choline-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine lesion Intestine Diet
New western diet (NWD) TD.96096
methionine-enriched
  J:145013 1 0
Intestine lesion Intestine Diet
high fiber
New western diet (NWD) TD.96096
  J:145013 1 0
Intestine neoplasm Intestine None (spontaneous)
  J:235854 2 0 - 4
Intestine normal tissue (control) Intestine None (spontaneous)
  J:94310 1 not applicable
Intestine polyp Intestine None (spontaneous)
  J:221412
J:53065
2 0 - observed
Intestine tumor Intestine None (spontaneous)
  J:204691
J:221412
2 0 - observed
Intestine tumor Intestine Chemical/Drug
BEZ235 (NVP-BEZ235-AN)
  J:204691 1 0
Intestine tumor Intestine Diet
(see notes regarding diet)
  J:145013 1 observed
Intestine tumor Intestine Diet
AIN-76A
  J:145013 3 0 - 26.67
Intestine tumor Intestine Diet
New western diet (NWD) TD.96096
  J:145013 3 0 - 53.33
Intestine tumor Intestine Diet
Calcium-enriched
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
New western diet (NWD) TD.96096
  J:145013 1 15.38
Intestine tumor Intestine Diet
Folic acid-enriched
New western diet (NWD) TD.96096
  J:145013 3 7.14 - 44.44
Intestine tumor Intestine Diet
New western diet (NWD) TD.96096
choline-enriched
  J:145013 1 20
Intestine tumor Intestine Diet
New western diet (NWD) TD.96096
methionine-enriched
  J:145013 1 22.22
Intestine tumor Intestine Diet
high fiber
New western diet (NWD) TD.96096
  J:145013 1 6.25
Intestine tumor Intestine Diet
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
New western diet (NWD) TD.96096
Calcium-enriched
  J:145013 1 13.64
Intestine tumor Intestine Diet
choline-enriched
New western diet (NWD) TD.96096
  J:145013 2 13.04 - 33.33
Intestine tumor Intestine Diet
methionine-enriched
New western diet (NWD) TD.96096
  J:145013 2 22.22 - 37.5
Intestine tumor Intestine Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 2 5.88 - 35.29
Intestine tumor Intestine Diet
Calcium-enriched
New western diet (NWD) TD.96096
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 5.56
Kidney - Cortex cyst Kidney - Cortex None (spontaneous)
  J:143281 1 7.7
Kidney - Cortex cyst Kidney - Cortex Diet
calorie restricted
  J:143281 1 0
Kidney - Renal tubule cyst Kidney - Renal tubule None (spontaneous)
  J:122261 1 observed
Kidney adenoma Kidney None (spontaneous)
  J:236844 2 0
Kidney cyst Kidney None (spontaneous)
  J:122261 2 observed
Kidney cyst - macrocyst Kidney None (spontaneous)
  J:232380 2 2 - 4
Kidney cyst - microcyst Kidney None (spontaneous)
  J:232380 2 4
Kidney lesion Kidney None (spontaneous)
  J:256619 2 2.0 - 10
Kidney lesion Kidney Diet
calorie restricted
  J:256619 4 0 - 4.0
Kidney metaplasia - osseous Kidney None (spontaneous)
  J:232380 2 0 - 2
Kidney normal tissue (control) Kidney None (spontaneous)
  J:94310
J:94320
3 not applicable
Kidney transitional cell hyperplasia Kidney None (spontaneous)
  J:232380 2 0 - 2
Kidney tumor - round cell Kidney None (spontaneous)
  J:143281 1 0
Kidney tumor - round cell Kidney Diet
calorie restricted
  J:143281 1 0
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell None (spontaneous)
  J:236844 2 0
Leukocyte - Lymphocyte - B-lymphocyte tumor Leukocyte - Lymphocyte - B-lymphocyte Other
jet-lag light cycle
  J:237981 1 observed
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus Radiation
gamma-radiation
  J:138632
J:177185
2 observed - 100
Leukocyte - Lymphocyte - T-lymphocyte normal tissue (control) Thymus Radiation
gamma-radiation
  J:138632 1 not applicable
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous)
  J:2434
J:55930
4 0 - 6
Leukocyte - Lymphocyte leukemia - lymphocytic Lung None (spontaneous)
  J:143281 1 7.7
Leukocyte - Lymphocyte leukemia - lymphocytic Spleen None (spontaneous)
  J:143281 1 0
Leukocyte - Lymphocyte leukemia - lymphocytic Liver None (spontaneous)
  J:143281 1 7.7
Leukocyte - Lymphocyte leukemia - lymphocytic Lung Diet
calorie restricted
  J:143281 1 0
Leukocyte - Lymphocyte leukemia - lymphocytic Spleen Diet
calorie restricted
  J:143281 1 6.7
Leukocyte - Lymphocyte leukemia - lymphocytic Liver Diet
calorie restricted
  J:143281 1 0
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 50
Leukocyte - Lymphocyte normal tissue (control) Lymph node None (spontaneous)
  J:94320 2 not applicable
Leukocyte - Lymphocyte normal tissue (control) Spleen - White pulp None (spontaneous)
  J:94320 1 not applicable
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous)
  J:1341
J:235854
J:236843
J:236844
7 0 - 51
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung None (spontaneous)
  J:143281 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Abdominal cavity None (spontaneous)
  J:143281 1 7.7
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous)
  J:143281
J:236844
3 0 - 15
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver None (spontaneous)
  J:143281
J:232380
3 0 - 12
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node None (spontaneous)
  J:143281 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung Diet
calorie restricted
  J:143281 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Abdominal cavity Diet
calorie restricted
  J:143281 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen Diet
calorie restricted
  J:143281 1 10
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver Diet
calorie restricted
  J:143281 1 23
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node Diet
calorie restricted
  J:143281 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node - Mesenteric None (spontaneous)
  J:122261 1 observed
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Uterus None (spontaneous)
  J:236843 1 observed
Leukocyte - Monocyte - Macrophage - Kupffer cell sarcoma Liver Diet
(see notes regarding diet)
  J:145013 1 observed
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Liver None (spontaneous)
  J:232380 2 0 - 2
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous)
  J:236844 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous)
  J:236844 2 0
Leukocyte - Myelocyte (Granulocyte) normal tissue (control) Spleen None (spontaneous)
  J:94320 1 not applicable
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 0
Leukocyte leukemia Leukocyte None (spontaneous)
  J:223430
J:22741
J:24831
6 0 - 16
Leukocyte leukemia Leukocyte Virus
Friend leukemia virus - "regressing" (RFV)
  J:25401 1 0
Leukocyte leukemia Leukocyte Virus
Friend leukemia virus - "conventional" (CFV)
  J:25401 1 0
Leukocyte leukemia Leukocyte Chemical/Drug
1-ethyl-1-nitrosourea (ENU)
  J:24831 1 20
Leukocyte leukemia Leukocyte Radiation
Cesium-137
  J:223430 2 0
Leukocyte lymphoma Leukocyte None (spontaneous)
  J:1341
J:223430
J:235854
J:236843
J:236844
J:81055
10 0 - 57
Leukocyte lymphoma Leukocyte Diet
zinc-deficient
  J:81055 1 0
Leukocyte lymphoma Kidney None (spontaneous)
  J:143281
J:256619
3 0 - 14
Leukocyte lymphoma Lung None (spontaneous)
  J:143281
J:256619
3 0 - 20
Leukocyte lymphoma Thymus None (spontaneous)
  J:143281 1 0
Leukocyte lymphoma Spleen None (spontaneous)
  J:143281
J:256619
3 0 - 12
Leukocyte lymphoma Liver None (spontaneous)
  J:143281
J:232380
J:256619
5 6.0 - 8
Leukocyte lymphoma Pancreas None (spontaneous)
  J:143281 1 0
Leukocyte lymphoma Lymph node None (spontaneous)
  J:143281 1 15
Leukocyte lymphoma Kidney Diet
calorie restricted
  J:143281
J:256619
5 0 - 6.7
Leukocyte lymphoma Lung Diet
calorie restricted
  J:143281
J:256619
5 0 - 2.0
Leukocyte lymphoma Thymus Diet
calorie restricted
  J:143281 1 3.3
Leukocyte lymphoma Spleen Diet
calorie restricted
  J:143281
J:256619
5 0 - 6.7
Leukocyte lymphoma Liver Diet
calorie restricted
  J:143281
J:256619
5 0 - 10
Leukocyte lymphoma Pancreas Diet
calorie restricted
  J:143281 1 0
Leukocyte lymphoma Lymph node Diet
calorie restricted
  J:143281 1 10
Leukocyte lymphoma Leukocyte Radiation
Cesium-137
  J:223430 2 5.3 - 21
Leukocyte lymphoma Heart None (spontaneous)
  J:256619 2 0
Leukocyte lymphoma Heart Diet
calorie restricted
  J:256619 4 0
Leukocyte lymphoma - lymphosarcoma Leukocyte None (spontaneous)
  J:223430 2 0
Leukocyte lymphoma - lymphosarcoma Leukocyte Radiation
Cesium-137
  J:223430 2 0 - 5.3
Leukocyte lymphoma - non-Hodgkin Leukocyte Diet
(see notes regarding diet)
  J:145013 2 observed - 3.93
Leukocyte lymphoma - non-Hodgkin Leukocyte Diet
AIN-76A
  J:145013 1 observed
Leukocyte neoplasia Leukocyte None (spontaneous)
  J:236843 1 67
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous)
  J:236844 2 0
Liver - Bile duct cyst - macrocyst Liver - Bile duct None (spontaneous)
  J:232380 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous)
  J:236844 2 0
Liver - Hepatocyte foci - basophilic Liver - Hepatocyte Chemical/Drug
N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)
  J:49724 1 observed
Liver - Hepatocyte foci - basophilic Liver - Hepatocyte Chemical/Drug
N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)
phenobarbital (PB)
  J:49724 1 observed
Liver - Hepatocyte foci - eosinophilic Liver - Hepatocyte Chemical/Drug
N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)
phenobarbital (PB)
  J:49724 1 observed
Liver adenoma Liver None (spontaneous)
  J:236843 1 1
Liver carcinoma Liver None (spontaneous)
  J:256619 2 0 - 2.0
Liver carcinoma Liver Diet
calorie restricted
  J:256619 4 0
Liver cyst Liver None (spontaneous)
  J:236843
J:256619
3 0 - 3
Liver cyst Liver Diet
calorie restricted
  J:256619 4 0
Liver cyst - macrocyst Liver None (spontaneous)
  J:232380 2 0 - 2
Liver cystadenoma Liver None (spontaneous)
  J:223430 2 0
Liver cystadenoma Liver Radiation
Cesium-137
  J:223430 2 0 - 14
Liver foci - clear cell Liver None (spontaneous)
  J:232380 2 0 - 2
Liver foci - eosinophilic Liver None (spontaneous)
  J:232380 2 0 - 2
Liver foci - vacuolated cell Liver None (spontaneous)
  J:232380 2 0
Liver hepatoblastoma Liver None (spontaneous)
  J:122261 1 observed
Liver hepatoblastoma Liver Diet
(see notes regarding diet)
  J:145013 1 observed
Liver hepatocellular adenoma Liver Chemical/Drug
phenobarbital (PB)
N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)
  J:49724 1 observed
Liver hepatocellular adenoma Liver None (spontaneous)
  J:232380 2 0 - 2
Liver hepatocellular carcinoma Liver None (spontaneous)
  J:122261
J:1341
J:232380
J:237981
5 0 - 8.8
Liver hepatocellular carcinoma Liver Chemical/Drug
N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)
  J:49724 1 observed
Liver hepatocellular carcinoma Liver Chemical/Drug
phenobarbital (PB)
N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)
  J:49724 1 observed
Liver hepatocellular carcinoma Liver Chemical/Drug
aflatoxin B1 (AFB1) (AFB1)
  J:85696 1 26.67
Liver hepatocellular carcinoma Liver Chemical/Drug
tricaprylin
  J:85696 1 0
Liver hepatocellular carcinoma Liver Other
jet-lag light cycle
  J:237981 3 observed - 8.75
Liver hepatocellular carcinoma Liver Diet
high saturated fat, high sucrose
  J:252310 1 observed
Liver hepatoma Liver None (spontaneous)
  J:236844 2 0
Liver hyperplasia Liver None (spontaneous)
  J:236843
J:237981
2 3 - 15.45
Liver hyperplasia Liver Other
jet-lag light cycle
  J:237981 1 75
Liver lesion Liver None (spontaneous)
  J:256619 2 0 - 12
Liver lesion Liver Diet
calorie restricted
  J:256619 4 0 - 26
Liver neoplasm Liver None (spontaneous)
  J:235854 4 0 - 4
Liver normal tissue (control) Liver None (spontaneous)
  J:94310
J:94320
3 not applicable
Liver tumor Liver Chemical/Drug
7,12-dimethylbenz[a]anthracene (DMBA)
  J:47091 1 observed
Liver tumor Liver None (spontaneous)
  J:19777
J:223649
J:2578
6 0 - 30
Liver tumor Liver Diet
(see notes regarding diet)
  J:145013 2 observed - 2.81
Liver tumor Liver Diet
AIN-76A
  J:145013 1 observed
Liver tumor Liver Diet
methionine-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Lung - Alveolus adenoma Lung - Alveolus Diet
(see notes regarding diet)
  J:145013 1 observed
Lung - Alveolus carcinoma Lung - Alveolus Diet
(see notes regarding diet)
  J:145013 1 observed
Lung - Bronchiole adenoma Lung - Bronchiole Diet
(see notes regarding diet)
  J:145013 1 observed
Lung - Bronchiole carcinoma Lung - Bronchiole Diet
(see notes regarding diet)
  J:145013 1 observed
Lung adenocarcinoma Lung None (spontaneous)
  J:236843 1 3
Lung adenoma Lung Chemical/Drug
urethane (ethyl carbamate)
  J:7050
J:796
J:8075
6 observed - 100
Lung adenoma Lung Chemical/Drug
1-ethyl-1-nitrosourea (ENU)
  J:24831 1 7.1
Lung adenoma Lung None (spontaneous)
  J:122261
J:175528
J:236843
J:236844
J:24831
J:256619
12 0 - very low
Lung adenoma Lung Chemical/Drug
urethane (ethyl carbamate)
butylated hydroxytoluene (BHT)
  J:7050 1 54
Lung adenoma Lung Diet
calorie restricted
  J:256619 4 0
Lung carcinoma Lung None (spontaneous)
  J:1341 1 11
Lung carcinoma Lung Chemical/Drug
N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)
  J:109061 1 0
Lung hyperplasia Lung None (spontaneous)
  J:236844 2 0
Lung neoplasm Lung None (spontaneous)
  J:235854 4 2 - 8
Lung normal tissue (control) Lung None (spontaneous)
  J:94313
J:94320
3 not applicable
Lung tumor Lung None (spontaneous)
  J:17778
J:2434
J:39931
5 0 - 3
Lung tumor Lung Radiation
uranium ore dust
  J:39931 2 0
Lung tumor Lung Radiation
radon
  J:39931 2 0
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
  J:157052
J:16946
J:39931
7 observed - 100
Lung tumor Lung Chemical/Drug
urethane (ethyl carbamate)
butylated hydroxytoluene (BHT)
  J:157052 1 100
Lung tumor Lung Diet
(see notes regarding diet)
  J:145013 2 observed - 4.21
Lung tumor Lung Diet
AIN-76A
  J:145013 1 observed
Lung tumor - malignant Lung None (spontaneous)
  J:256619 2 2.0 - 4.0
Lung tumor - malignant Lung Diet
calorie restricted
  J:256619 4 0 - 2.0
Lymph node cyst Lymph node None (spontaneous)
  J:236844 2 0
Lymph node hyperplasia Reticulocyte None (spontaneous)
  J:236844 2 0
Lymph node normal tissue (control) Lymph node None (spontaneous)
  J:94313 1 not applicable
Mammary gland adenocarcinoma Mammary gland None (spontaneous)
  J:2434 3 0 - 1
Mammary gland adenocarcinoma - intraductal Mammary gland None (spontaneous)
  J:94320 1 observed
Mammary gland neoplasm Mammary gland None (spontaneous)
  J:235854 2 0
Mammary gland normal tissue (control) Mammary gland None (spontaneous)
  J:94313
J:94320
4 not applicable
Mammary gland tumor Mammary gland None (spontaneous)
  J:24262
J:37506
J:55932
4 0 - 1
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma Intestine - Small Intestine - Brunner's gland None (spontaneous)
  J:122261 1 observed
Mesodermal cell/mesoblast sarcoma Liver None (spontaneous)
  J:122261 1 observed
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous)
  J:236844 1 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous)
  J:236844 2 0
Mesodermal cell/mesoblast sarcoma - round cell Lung None (spontaneous)
  J:143281 1 0
Mesodermal cell/mesoblast sarcoma - round cell Liver None (spontaneous)
  J:143281 1 7.7
Mesodermal cell/mesoblast sarcoma - round cell Lymph node None (spontaneous)
  J:143281 1 7.7
Mesodermal cell/mesoblast sarcoma - round cell Lung Diet
calorie restricted
  J:143281 1 3.3
Mesodermal cell/mesoblast sarcoma - round cell Liver Diet
calorie restricted
  J:143281 1 6.7
Mesodermal cell/mesoblast sarcoma - round cell Lymph node Diet
calorie restricted
  J:143281 1 6.7
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous)
  J:236844 1 0
Mesothelium foci Mesothelium Chemical/Drug
crocidolite asbestos
  J:116125 1 18.18
Mesothelium mesothelioma Mesothelium Chemical/Drug
crocidolite asbestos
  J:116125 3 86.67 - 100
Mesothelium mesothelioma Mesothelium None (spontaneous)
  J:116125 1 0
Mesothelium mesothelioma - malignant - sarcomatoid Mesothelium Chemical/Drug
crocidolite asbestos
  J:116125 1 18.18
Mesothelium tumor - benign Mesothelium Chemical/Drug
crocidolite asbestos
  J:116125 1 45.45
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous)
  J:236844 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous)
  J:236844 1 0
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous)
  J:236844 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous)
  J:236843
J:236844
3 0 - 3
Muscle - Smooth leiomyosarcoma Seminal vesicle None (spontaneous)
  J:236843 1 4
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Colon None (spontaneous)
  J:236843 1 1
Muscle - Smooth leiomyosarcoma (Unspecified organ) Diet
(see notes regarding diet)
  J:145013 1 observed
Muscle - Striated - Skeletal normal tissue (control) Muscle - Striated - Skeletal None (spontaneous)
  J:94320 2 not applicable
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous)
  J:236844 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous)
  J:176506 1 0
Myoepithelial cell myoepithelioma Lung None (spontaneous)
  J:236844 2 0
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous)
  J:236844 2 0
Nail dysplasia Nail None (spontaneous)
  J:122261 1 observed
Nail squamous cell carcinoma Nail None (spontaneous)
  J:122261
J:236844
3 0 - observed
Nerve normal tissue (control) Nerve None (spontaneous)
  J:94313
J:94320
2 not applicable
Oral cavity normal tissue (control) Oral cavity None (spontaneous)
  J:94310
J:94320
2 not applicable
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous)
  J:236844 1 low
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous)
  J:223430
J:236843
J:236844
3 0 - 2
Ovary - Granulosa cell tumor Ovary - Granulosa cell Radiation
Cesium-137
  J:223430 1 5.3
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous)
  J:236844 1 0
Ovary - Sex cord stromal cell adenoma - tubulostromal Ovary - Sex cord stromal cell None (spontaneous)
  J:122261 2 observed
Ovary adenoma Ovary None (spontaneous)
  J:236844 1 0
Ovary cyst Ovary None (spontaneous)
  J:236843 1 4
Ovary cyst - bursal Ovary None (spontaneous)
  J:236844 1 0
Ovary cystadenoma Ovary None (spontaneous)
  J:223430 1 0
Ovary cystadenoma Ovary Radiation
Cesium-137
  J:223430 1 42
Ovary hyperplasia - epithelial Ovary None (spontaneous)
  J:236844 1 0
Ovary luteoma Ovary None (spontaneous)
  J:122261 1 observed
Ovary neoplasm Ovary None (spontaneous)
  J:235854 1 1
Ovary tumor Ovary None (spontaneous)
  J:223430 1 0
Ovary tumor Ovary Radiation
Cesium-137
  J:223430 1 47
Ovary tumor Ovary Other
jet-lag light cycle
  J:237981 1 observed
Ovary tumor - tubulostromal Ovary None (spontaneous)
  J:236844 1 0
Oviduct hyperplasia Oviduct None (spontaneous)
  J:94320 2 observed
Oviduct normal tissue (control) Oviduct None (spontaneous)
  J:94320 2 not applicable
PNS - Nerve sheath tumor Ear None (spontaneous)
  J:236844 2 0
PNS - Nerve sheath tumor Skin None (spontaneous)
  J:236844 2 0
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous)
  J:236844 2 0
Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell None (spontaneous)
  J:76997 1 0
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous)
  J:122261 3 observed
Pancreas neoplasm Pancreas None (spontaneous)
  J:235854 2 0
Pancreas normal tissue (control) Pancreas None (spontaneous)
  J:94310
J:94320
3 not applicable
Pancreas tumor Pancreas Other
jet-lag light cycle
  J:237981 1 observed
Peritoneum - Mesentery hyperplasia Peritoneum - Mesentery None (spontaneous)
  J:236843 1 observed
Peyer's patch normal tissue (control) Peyer's patch None (spontaneous)
  J:94320 1 not applicable
Pituitary gland - Pars distalis adenocarcinoma Pituitary gland - Pars distalis None (spontaneous)
  J:236843 1 1
Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis None (spontaneous)
  J:143281
J:232380
3 0 - 31
Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis Diet
calorie restricted
  J:143281 1 3.3
Pituitary gland - Pars distalis cyst - microcyst Pituitary gland - Pars distalis None (spontaneous)
  J:232380 2 0 - 2
Pituitary gland - Pars distalis hyperplasia - focal Pituitary gland - Pars distalis None (spontaneous)
  J:232380 2 0 - 12
Pituitary gland - Pars distalis tumor Pituitary gland - Pars distalis None (spontaneous)
  J:50509 3 0 - 83
Pituitary gland - Pars intermedia adenoma Pituitary gland - Pars intermedia None (spontaneous)
  J:122261
J:232380
3 0 - observed
Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia None (spontaneous)
  J:232380 2 0 - 4
Pituitary gland adenoma Pituitary gland None (spontaneous)
  J:1341
J:236843
2 0 - 6
Pituitary gland carcinoma Pituitary gland None (spontaneous)
  J:232380 2 0 - 2
Pituitary gland cyst - microcyst Pituitary gland None (spontaneous)
  J:232380 2 2
Pituitary gland hyperplasia Pituitary gland None (spontaneous)
  J:24262 1 observed
Pituitary gland hyperplasia - focal Pituitary gland None (spontaneous)
  J:232380 2 0
Pituitary gland neoplasm Pituitary gland None (spontaneous)
  J:235854 4 0 - 7
Pituitary gland tumor Pituitary gland None (spontaneous)
  J:235854
J:24262
9 0 - 61
Pituitary gland tumor Pituitary gland Hormone
ovariectomy
  J:24262 1 very low
Placenta normal tissue (control) Placenta None (spontaneous)
  J:94313
J:94320
3 not applicable
Preputial/Clitoral gland (sex not specified) normal tissue (control) Preputial/Clitoral gland (sex not specified) None (spontaneous)
  J:94310
J:94313
J:94320
3 not applicable
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous)
  J:236844 1 0
Prostate gland normal tissue (control) Prostate gland None (spontaneous)
  J:94320 1 not applicable
Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland None (spontaneous)
  J:144924 1 observed
Salivary gland - Parotid hyperplasia Salivary gland - Parotid None (spontaneous)
  J:122261 1 observed
Salivary gland normal tissue (control) Salivary gland None (spontaneous)
  J:94313
J:94320
3 not applicable
Seminal vesicle normal tissue (control) Seminal vesicle None (spontaneous)
  J:94320 1 not applicable
Skin - Dorsal region adenoma - sebaceous Skin - Dorsal region None (spontaneous)
  J:94307 1 observed
Skin - Dorsal region papilloma Skin - Dorsal region None (spontaneous)
  J:94307 1 observed
Skin - Dorsal region tumor Skin - Dorsal region Virus
mouse papillomavirus (MmuPV1)
  J:217142 1 0
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous)
  J:236844 2 0
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous)
  J:236844 2 0
Skin - Epidermis hamartoma Skin - Epidermis None (spontaneous)
  J:94310 1 observed
Skin - Epidermis hyperplasia Skin - Epidermis None (spontaneous)
  J:94307 1 observed
Skin - Facial region tumor Skin - Facial region Virus
mouse papillomavirus (MmuPV1)
  J:217142 1 0
Skin - Hair follicle hyperplasia Skin - Hair follicle None (spontaneous)
  J:94307 1 observed
Skin - Tail tumor Skin - Tail Virus
mouse papillomavirus (MmuPV1)
  J:217142 1 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous)
  J:236844 2 0
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous)
  J:236844 2 0
Skin hyperplasia Skin None (spontaneous)
  J:94307 5 observed
Skin hyperplasia - epithelial Ear None (spontaneous)
  J:236844 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous)
  J:236844 2 0
Skin lesion Skin Chemical/Drug
7,12-dimethylbenz[a]anthracene (DMBA)
12-O-tetradecanoylphorbol-13-acetate (TPA)
  J:72579 1 observed
Skin lesion Skin Virus
mouse papillomavirus (MmuPV1)
  J:217142 1 0
Skin normal tissue (control) Skin None (spontaneous)
  J:94310
J:94313
J:94320
5 not applicable
Skin papilloma Skin Chemical/Drug
7,12-dimethylbenz[a]anthracene (DMBA)
12-O-tetradecanoylphorbol-13-acetate (TPA)
  J:72579 1 very high
Skin squamous cell carcinoma Skin None (spontaneous)
  J:144924
J:236843
2 observed - 1
Skin tumor Skin Chemical/Drug
7,12-dimethylbenz[a]anthracene (DMBA)
12-O-tetradecanoylphorbol-13-acetate (TPA)
  J:43880 1 42
Skin tumor Skin None (spontaneous)
  J:1341
J:55930
2 0 - 11
Spleen normal tissue (control) Spleen None (spontaneous)
  J:94320 2 not applicable
Spleen tumor Spleen None (spontaneous)
  J:256619 2 0 - 6.0
Spleen tumor Spleen Diet
calorie restricted
  J:256619 4 0 - 10
Spleen tumor - round cell Spleen None (spontaneous)
  J:143281 1 0
Spleen tumor - round cell Spleen Diet
calorie restricted
  J:143281 1 0
Stomach - Epithelium hyperplasia - squamous Stomach - Epithelium None (spontaneous)
  J:122261 1 observed
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous)
  J:236844 2 0 - low
Stomach - Glandular cyst Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous)
  J:236844 2 0 - low
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous)
  J:236844 2 0 - low
Stomach - Glandular normal tissue (control) Stomach - Glandular None (spontaneous)
  J:94320 1 not applicable
Stomach - Glandular polyp Stomach - Glandular None (spontaneous)
  J:236844 2 0
Stomach adenocarcinoma Stomach None (spontaneous)
  J:38850 1 0
Stomach adenoma Stomach None (spontaneous)
  J:38850 1 0
Stomach adenoma - microadenoma Stomach Diet
AIN-76A
  J:145013 1 0
Stomach adenoma - microadenoma Stomach Diet
New western diet (NWD) TD.96096
  J:145013 3 0 - observed
Stomach adenoma - microadenoma Stomach Diet
New western diet (NWD) TD.96096
Calcium-enriched
vitamin D3 (1alpha,25-(OH)2-D3) (VD3)
  J:145013 1 0
Stomach adenoma - microadenoma Salivary gland Diet
Folic acid-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Stomach adenoma - microadenoma Stomach Diet
choline-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Stomach adenoma - microadenoma Stomach Diet
methionine-enriched
New western diet (NWD) TD.96096
  J:145013 1 0
Stomach adenoma - microadenoma Stomach Diet
New western diet (NWD) TD.96096
high fiber
  J:145013 1 0
Stomach normal tissue (control) Stomach None (spontaneous)
  J:94310
J:94320
2 not applicable
Stomach squamous cell papilloma Stomach None (spontaneous)
  J:236843 1 3
Testis - Germ cell normal tissue (control) Testis - Germ cell None (spontaneous)
  J:94320 1 not applicable
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236843 1 4
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236844 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236844 1 0
Testis - Leydig cell (Interstitial cell) normal tissue (control) Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:94320 1 not applicable
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous)
  J:236844 1 0
Testis normal tissue (control) Testis None (spontaneous)
  J:94320 1 not applicable
Thymus normal tissue (control) Thymus None (spontaneous)
  J:94313
J:94320
3 not applicable
Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell None (spontaneous)
  J:122261 3 observed
Thyroid gland - Follicular cell hyperplasia Thyroid gland - Follicular cell None (spontaneous)
  J:94320 1 observed
Thyroid gland adenoma Thyroid gland None (spontaneous)
  J:122261 2 observed
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous)
  J:122261
J:236844
4 0 - low
Thyroid gland neoplasm Thyroid gland None (spontaneous)
  J:235854 2 0
Tongue normal tissue (control) Tongue None (spontaneous)
  J:94310
J:94320
5 not applicable
Tooth dysplasia Tooth None (spontaneous)
  J:122261
J:236843
3 observed
Trachea normal tissue (control) Trachea None (spontaneous)
  J:94310
J:94320
3 not applicable
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous)
  J:236844 2 0
Ureter hyperplasia Ureter None (spontaneous)
  J:122261 1 observed
Ureter hyperplasia Muscle - Smooth None (spontaneous)
  J:236844 2 0
Ureter polyp Ureter None (spontaneous)
  J:236844 2 0 - very low
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous)
  J:236844 2 0
Urinary bladder - Transitional cell normal tissue (control) Urinary bladder - Transitional cell None (spontaneous)
  J:94320 1 not applicable
Urinary bladder normal tissue (control) Urinary bladder None (spontaneous)
  J:94313
J:94320
3 not applicable
Urinary bladder papilloma Urinary bladder None (spontaneous)
  J:236844 2 0
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous)
  J:122261
J:236843
J:236844
4 observed - moderate
Uterus - Endometrium normal tissue (control) Uterus - Endometrium None (spontaneous)
  J:94320 2 not applicable
Uterus adenoma Uterus None (spontaneous)
  J:236844 1 0
Uterus fibropapilloma Uterus None (spontaneous)
  J:236844 1 0
Uterus neoplasm Uterus None (spontaneous)
  J:235854 1 4
Uterus normal tissue (control) Uterus None (spontaneous)
  J:94310
J:94320
3 not applicable
Vagina normal tissue (control) Vagina None (spontaneous)
  J:94320 1 not applicable
Vagina papilloma Vagina None (spontaneous)
  J:236844 1 0
Vulva squamous cell carcinoma Vulva None (spontaneous)
  J:236844 1 0
(Unspecified organ) neoplasm (Unspecified organ) None (spontaneous)
  J:235854 4 35 - 50
(Unspecified organ) reticulum cell sarcoma (Unspecified organ) None (spontaneous)
  J:55930 1 9
(Unspecified organ) tumor (Unspecified organ) None (spontaneous)
  J:1341
J:223430
J:22621
J:237981
J:55932
7 0 - low
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug
1-ethyl-1-nitrosourea (ENU)
  J:24831 1 2.4
(Unspecified organ) tumor (Unspecified organ) Radiation
Cesium-137
  J:223430 2 36 - 58
(Unspecified organ) tumor (Unspecified organ) Other
jet-lag light cycle
  J:237981 1 observed
(Unspecified organ) tumor (Unspecified organ) Diet
(see notes regarding diet)
  J:145013 4 observed - 14.47
(Unspecified organ) tumor (Unspecified organ) Diet
AIN-76A
  J:145013 2 observed - 6.67
(Unspecified organ) tumor (Unspecified organ) Diet
high fiber
New western diet (NWD) TD.96096
  J:145013 1 0
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=7
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/C57BL.shtml
JAX Mice http://jaxmice.jax.org/strain/000664.html