Strain Summary[not specified]-Ptentm2Mak Ralgapa2tm1Hhor Tg(KLKB1-cre/ERT2)1Pcn

Strain Name

[not specified]-Ptentm2Mak Ralgapa2tm1Hhor Tg(KLKB1-cre/ERT2)1Pcn

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

PSA-Cre-ERT2;Ptenflox/flox;Ralgapa2-/-  •  Ralgapa2-/-

Description

Homozygous Pten, Ralgapa2 mice carrying the transgene on an unspecified background with contribution from C57BL/6J and 129P2/OlaHsd.

Strain Genetics

Tg(KLKB1-cre/ERT2)1Pcn
Tg(KLKB1-cre/ERT2)1Pcn

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Prostate gland hyperplasia Prostate gland

0

References: Uegaki M, Carcinogenesis 2019 Dec 31;40(12):1535-1544

Prostate gland lesion - neoplastic Prostate gland tamoxifen (For inducing expression from mutant alleles)

100

References: Uegaki M, Carcinogenesis 2019 Dec 31;40(12):1535-1544

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

0

References: Uegaki M, Carcinogenesis 2019 Dec 31;40(12):1535-1544

Prostate gland prostatic intraepithelial neoplasia - high grade (HGPIN) Prostate gland tamoxifen (For inducing expression from mutant alleles)

observed

References: Uegaki M, Carcinogenesis 2019 Dec 31;40(12):1535-1544