Strain SummaryC57BL/6-Krastm1.1Khai/+ Tg(Pdx1-cre)6Tuv

Strain Name

C57BL/6-Krastm1.1Khai/+ Tg(Pdx1-cre)6Tuv

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

A146T  •  Pdx1-Cre; KrasLSL-A146T

Description

Heterozygous Kras mice carrying the transgene on a primarily C57BL/6 background (80-95%) with contribution from FVB/N, 129S4/SvJae, and 129S6/SvEvTac.

Strain Genetics

Krastm1.1Khai / Kras+
Tg(Pdx1-cre)6Tuv

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas pancreatic intraepithelial neoplasia (PanIN) Pancreas

0

References: Poulin EJ, Cancer Discov 2019 Jun;9(6):738-755

Pancreas pancreatic intraepithelial neoplasia (PanIN) Pancreas cerulein

0

References: Poulin EJ, Cancer Discov 2019 Jun;9(6):738-755