Strain Summary[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ Ptgs2tm1Hahe Trp53tm1Brn

Strain Name

[not specified]-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor Krastm3Tyj/+ Krt5tm1.1(cre/ERT2)Blh/+ Ptgs2tm1Hahe Trp53tm1Brn

Strain Type(s)

gene trapped  •  targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

K15-CrePR; LSLKrasG12D; p53flox/flox; Ptgs2wt/wt

Description

Heterozygous Krt15, ROSA, Kras, homozygous Trp53, Ptgs2 mice on an unspecified background with possible contributions from 129S6/SvEvTac, C57BL/6J, SJL/J, C57BL/6NCrl, 129P2/OlaHsd, and 129S4/SvJae.

Strain Genetics

Tg(Krt1-15-cre/PGR)22Cot
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze / Gt(ROSA)26Sor
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze / Gt(ROSA)26Sor
Krastm3Tyj / Kras+
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze / Gt(ROSA)26Sor
Tg(Krt1-15-cre/PGR)22Cot
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze / Gt(ROSA)26Sor

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach RU-486

13.33 - 26.67

References: Moon H, Nat Commun 2019 May 20;10(1):2225