Strain SummaryC57BL/6-Braftm1Mmcm/+

Strain Name

C57BL/6-Braftm1Mmcm/+

Strain Type(s)

targeted mutation (conditional)

Strain Synonym(s)

BrafCA/+  •  Brafthyr-V600E

Description

Heterozygous Braf mice on a B6 background with contribution from 129P2/OlaHsd and 129S1/Sv.

Strain Genetics

Braftm1Mmcm / Braf+
Braftm1Mmcm / Braf+

Models

12 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung tumor - nodular Lung Adenovirus - recombinant, expressing Cre recombinase

22.22

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland adenoma Thyroid gland

0

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland adenoma Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

0

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland atypia Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

observed

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland hyperplasia Thyroid gland

0

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland hyperplasia Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

0

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland tumor Thyroid gland

0

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland tumor Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

0 - 88.89

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland tumor - cribriform Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

high

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland tumor - follicular Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

high

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland tumor - malignant Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

observed

References: Shimamura M, PLoS One 2018;13(8):e0201365

Thyroid gland tumor - papillary Thyroid gland Adenovirus - recombinant, expressing Cre recombinase

22.22

References: Shimamura M, PLoS One 2018;13(8):e0201365