Strain SummaryC57BL/6-Krastm4Tyj/+ Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/+

Strain Name

C57BL/6-Krastm4Tyj/+ Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/+

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

AKPP  •  Alb-Cre+; LSL-KrasG12D/+; Ptenflox/flox

Description

Compound mutant mice. The genetic background of this cohort was stated to be C57BL/6. It may have also contained some DBA, 129P2/OlaHsd, 129S4/SvJae, and/or other strain(s).

Strain Genetics

Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1+
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1+
Krastm4Tyj / Kras+
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1+

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Liver - Bile duct cholangiocarcinoma Liver - Bile duct

observed

References: Ikenoue T, Sci Rep 2016 Apr 1;6(None):23899

2 pathology image(s)

Liver - Bile duct dysplasia Liver - Bile duct

observed

References: Ikenoue T, Sci Rep 2016 Apr 1;6(None):23899

Liver - Bile duct hyperplasia Liver - Bile duct

observed

References: Ikenoue T, Sci Rep 2016 Apr 1;6(None):23899

Liver - Bile duct hyperplasia - papillary Liver - Bile duct

observed

References: Ikenoue T, Sci Rep 2016 Apr 1;6(None):23899

1 pathology image(s)

Liver tumor Liver

100

References: Ikenoue T, Sci Rep 2016 Apr 1;6(None):23899