Strain SummaryC57BL/6N-Apctm1Rak/+ Myd88tm1Hlz

Strain Name

C57BL/6N-Apctm1Rak/+ Myd88tm1Hlz

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)

Strain Synonym(s)

Apc1638N/+ MyD88LSL

Description

Heterozygous Apc mutant mice on a C57BL/6N background with contribution from C57BL/6, DBA/2, and 129P2/OlaHsd. All parental strains were backcrossed to C57BL/6N for greater than 10 generations.

Strain Genetics

Apctm1Rak / Apc+

Models

22 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon lesion Intestine - Large Intestine - Colon

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Distal lesion Intestine - Small Intestine - Distal

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Duodenum lesion Intestine - Small Intestine - Duodenum

0 - 50

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Duodenum tumor Intestine - Small Intestine - Duodenum

0 - 50

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Ileum lesion Intestine - Small Intestine - Ileum

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Ileum tumor Intestine - Small Intestine - Ileum

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Jejunum lesion Intestine - Small Intestine - Jejunum

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Jejunum tumor Intestine - Small Intestine - Jejunum

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Proximal lesion Intestine - Small Intestine - Proximal

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine adenoma Intestine

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine carcinoma - invasive Intestine

0

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine dysplasia Intestine

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine dysplasia - low grade Intestine

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine hyperplasia Intestine

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine lesion Intestine

42.86

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine neoplasia - intraepithelial - high-grade Intestine

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine neoplasia - intraepithelial - low-grade Intestine

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Intestine tumor Intestine

observed - 42.86

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770

Spleen hyperplasia Spleen

observed

References: Holtorf A, Oncoimmunology 2018;7(8):e1466770