Strain SummaryC57BL/6- Cdkn2atm4Rdp Pcgf2tm1Rxi Tg(Vil1-cre)997Gum

Strain Name

C57BL/6- Cdkn2atm4Rdp Pcgf2tm1Rxi Tg(Vil1-cre)997Gum

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Mel18DeltaIEC/Cdkn2aDeltaIEC

Description

Compound mutant mice on a C57BL/6 background with contribution from C57BL/6J, SJL, and an unspecified 129 substrain. Parental mice were backcrossed to C57BL/6 for at least 6 generations and bred to create experimental mice.

Strain Genetics

Tg(Vil1-cre)997Gum

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

observed

References: Liu X, Gastroenterology 2017 Dec;153(6):1607-1620