Strain Summary[not specified]-Stk11tm2Tpm/+ Twist2tm1.1(cre)Dor

Strain Name

[not specified]-Stk11tm2Tpm/+ Twist2tm1.1(cre)Dor

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Lkb1TwKO/+  •  Twist2-Cre;Lkb1fl/+  •  TwKO/+

Description

Heterozygous Stk11 mutant mice that carried the transgene on an unspecified mixed background that included contribution from 129X1/SvJ.

Strain Genetics

Twist2tm1.1(cre)Dor / Twist2+
Twist2tm1.1(cre)Dor / Twist2+
Stk11tm2Tpm / Stk11+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine polyp Intestine

observed

References: Ollila S, J Clin Invest 2018 Jan 2;128(1):402-414

Stomach polyp Stomach

observed - 100

References: Ollila S, J Clin Invest 2018 Jan 2;128(1):402-414