Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
BALB/cJ-Tg(Actb-Mdm4)6Glo Trp53tm2.1Tyj/+
Strain Synonyms Mdm4Tg6 p53R172H/+
Strain Note: Compound mutant mice. The genetic background of these mice was predominantly BALB/cJ as this cohort was generated from crossing congenic strains. There was also some contribution from 129S4/SvJae and possibly some other strain(s).
Strain Tumor Overview Expanded View
Tumors 15 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 32
Bone osteosarcoma Bone None (spontaneous) 1 3.6
Leukocyte lymphoma Leukocyte None (spontaneous) 1 68
Lung adenoma Lung None (spontaneous) 1 11
Lung carcinoma Lung None (spontaneous) 1 11
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 1 14
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 32.0 - 46.0
Mesodermal cell/mesoblast sarcoma Salivary gland None (spontaneous) 1 3.6
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous) 1 3.6
Testis - Leydig cell (Interstitial cell) carcinoma Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 14
(Unspecified organ) carcinoma (Unspecified organ) None (spontaneous) 1 14.0 - 39.0
(Unspecified organ) sarcoma - spindle cell (Unspecified organ) None (spontaneous) 1 3.6
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 100
(Unspecified organ) tumor - anaplastic (Unspecified organ) None (spontaneous) 1 3.6
(Unspecified organ) tumor - spindle cell (Unspecified organ) None (spontaneous) 1 3.6