Strain Summary[not specified]-Gt(ROSA)26Sortm1(cre/ERT2)Alj Igs2tm1(ACTB-EGFP,-tdTomato)Luo/Igs2tm2(ACTB-tdTomato,-EGFP)Luo Krastm3Tyj/+

Strain Name

[not specified]-Gt(ROSA)26Sortm1(cre/ERT2)Alj Igs2tm1(ACTB-EGFP,-tdTomato)Luo/Igs2tm2(ACTB-tdTomato,-EGFP)Luo Krastm3Tyj/+

Strain Type(s)

targeted mutation (knock-in)  •  targeted mutation (other)

Strain Synonym(s)

KrasLA2,Rosa26-CreERT2/KrasWT; MADM

Description

Compound mutant mice. The genetic background was an undefined mixture that included at least some 129S4/SvJae, and also 129X1/SvJ and/or 129S1/Sv. There may have been other strain contributions.

Strain Genetics

Gt(ROSA)26Sortm1(cre/ERT2)Alj
Igs2tm1(ACTB-EGFP,-tdTomato)Luo / Igs2tm2(ACTB-tdTomato,-EGFP)Luo
Igs2tm1(ACTB-EGFP,-tdTomato)Luo / Igs2tm2(ACTB-tdTomato,-EGFP)Luo
Krastm3Tyj / Kras+
Igs2tm1(ACTB-EGFP,-tdTomato)Luo / Igs2tm2(ACTB-tdTomato,-EGFP)Luo
Gt(ROSA)26Sortm1(cre/ERT2)Alj
Igs2tm1(ACTB-EGFP,-tdTomato)Luo / Igs2tm2(ACTB-tdTomato,-EGFP)Luo

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung tumor Lung tamoxifen (For inducing expression from mutant alleles)

0

References: Muzumdar MD, Nat Commun 2016 Sep 02;7():12685