Strain Summary[not specified]-Cdkn2atm4Rdp Nf1tm1Par

Strain Name

[not specified]-Cdkn2atm4Rdp Nf1tm1Par

Strain Type(s)

targeted mutation (conditional)

Strain Synonym(s)

Nf1Flox/Flox; Ink4a/ArfFlox/Flox

Description

Homozygous Cdkn2a, Nf1 mice on an unspecified background with contribution from C57BL/6, 129S2/SvPas, 129X1/SvJ, and 129S2/Sv.

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast Adenovirus carrying cre recombinase

100

References: Dodd RD, Cancer Res 2017 Aug 15;77(16):4486-4497

PNS - Nerve sheath tumor - malignant PNS - Nerve sheath Adenovirus carrying cre recombinase

observed - 100

References: Dodd RD, Cancer Res 2017 Aug 15;77(16):4486-4497

PNS - Nerve sheath tumor - malignant PNS - Nerve sheath ifosfamide   ⋅   Adenovirus carrying cre recombinase   ⋅   doxorubicin

observed

References: Dodd RD, Cancer Res 2017 Aug 15;77(16):4486-4497