Strain Summary[not specified]-Braftm1Mmcm/+ Trp53tm1Brn

Strain Name

[not specified]-Braftm1Mmcm/+ Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

BrafCA/+;p53flox/flox

Description

Heterozygous Braf, homozygous Trp53 mice on an unspecified background with contributions from 129P2/OlaHsd from the parental ES cells.

Strain Genetics

Braftm1Mmcm / Braf+
Braftm1Mmcm / Braf+

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mesodermal cell/mesoblast sarcoma (Unspecified organ) LUM015   ⋅   Adenovirus carrying cre recombinase

observed

References: Whitley MJ, Sci Transl Med 2016 Jan 6;8(320):320ra4

Mesodermal cell/mesoblast sarcoma (Unspecified organ) Adenovirus carrying cre recombinase

observed

References: Whitley MJ, Sci Transl Med 2016 Jan 6;8(320):320ra4

Mesodermal cell/mesoblast sarcoma (Unspecified organ) LUM015   ⋅   tumor removal   ⋅   Adenovirus carrying cre recombinase

observed

References: Whitley MJ, Sci Transl Med 2016 Jan 6;8(320):320ra4

(Unspecified organ) tumor (Unspecified organ) LUM015   ⋅   Adenovirus carrying cre recombinase

observed

References: Whitley MJ, Sci Transl Med 2016 Jan 6;8(320):320ra4

(Unspecified organ) tumor (Unspecified organ) Adenovirus carrying cre recombinase

observed

References: Whitley MJ, Sci Transl Med 2016 Jan 6;8(320):320ra4